Daniel Sage
EPFL STI IMT LIB
BM 4135 (Bâtiment BM)
Station 17
1015 Lausanne
+41 21 693 51 89
+41 21 693 91 32
Office: BM 4135
EPFL › STI › IEM › LIB
Site web: https://bigwww.epfl.ch/
+41 21 693 91 32
EPFL › SV › SV-SSV › SSV-ENS
Site web: https://sv.epfl.ch/education
+41 21 693 91 32
EPFL › STI › STI-SMT › SMT-ENS
EPFL IMAGING
ELE 130 (Bâtiment ELE)
Station 11
1015 Lausanne
+41 21 693 91 32
Office: BM 4135
EPFL › VPA › VPA-AVP-CP › IMAGING › IMAGING-GE
Expertise
Roadmap on Deep Learning for Microscopy
JOURNAL OF PHYSICS-PHOTONICS. 2026. DOI : 10.1088/2515-7647/ae0fd1.Revisiting PSF models: Unifying framework and high‐performance implementation
Journal of Microscopy. 2025. DOI : 10.1111/jmi.70045.Image Processing and Image Analysis in Microscopy
Photonic Imaging for Biology: From Conventional Microscopy to Super-Resolution; John Wiley and Sons Inc., 2025. p. 205 - 237.Back to the future–20 years of progress and developments in photonic microscopy and biological imaging
Journal of cell science. 2024. DOI : 10.1242/jcs.262344.Surpassing light inhomogeneities in structured-illumination microscopy with FlexSIM
Journal of microscopy. 2024. DOI : 10.1111/jmi.13344.JDLL: a library to run deep learning models on Java bioimage informatics platforms
Nature Methods. 2024. DOI : 10.1038/s41592-023-02129-x.A framework for evaluating the performance of SMLM cluster analysis algorithms
Nature Methods. 2023. DOI : 10.1038/s41592-022-01750-6.Correction of multiple-blinking artifacts in photoactivated localization microscopy
Nature Methods. 2022. DOI : 10.1038/s41592-022-01463-w.Steer'n'Detect: fast 2D template detection with accurate orientation estimation
Bioinformatics. 2022. DOI : 10.1093/bioinformatics/btac270.A Practical Guide to Supervised Deep Learning for Bioimage Analysis: Challenges and good practices
Ieee Signal Processing Magazine. 2022. DOI : 10.1109/MSP.2021.3123589.DeepImageJ: A user-friendly environment to run deep learning models in ImageJ
Nature Methods. 2021. DOI : 10.1038/s41592-021-01262-9.Deep Learning Enables Individual Xenograft Cell Classification in Histological Images by Analysis of Contextual Features
Journal of Mammary Gland Biology and Neoplasia. 2021. DOI : 10.1007/s10911-021-09485-4.Optimal-Transport-Based Metric for SMLM
2021. 18th IEEE International Symposium on Biomedical Imaging (ISBI'21), Nice, France, April 13-16, 2021. p. 797 - 801. DOI : 10.1109/ISBI48211.2021.9433874.Graphic: Graph-Based Hierarchical Clustering For Single-Molecule Localization Microscopy
2021. 18th IEEE International Symposium on Biomedical Imaging (ISBI), Nice, FRANCE, Apr 13-16, 2021. p. 1892 - 1896. DOI : 10.1109/ISBI48211.2021.9433760.In pancreatic islets from type 2 diabetes patients, the dampened circadian oscillators lead to reduced insulin and glucagon exocytosis
Proceedings Of The National Academy Of Sciences Of The United States Of America (PNAS). 2020. DOI : 10.1073/pnas.1916539117.Reconstruction Methods for Cryo-Electron Microscopy: From Model-based to Data-driven
Lausanne, EPFL, 2020. DOI : 10.5075/epfl-thesis-7540.W2S: Microscopy Data with Joint Denoising and Super-Resolution for Widefield to SIM Mapping
2020. ECCV 2020 Workshop on BioImage Computing, Glasgow, United Kingdom, August 23-28, 2020. p. 499 - 518. DOI : 10.1007/978-3-030-67070-2_30.Pocket guide to solve inverse problems with GlobalBioIm
Inverse Problems. 2019. DOI : 10.1088/1361-6420/ab2ae9.Super-resolution fight club: assessment of 2D and 3D single-molecule localization microscopy software
Nature Methods. 2019. DOI : 10.1038/s41592-019-0364-4.Deforming Tessellations for the Segmentation of Cell Aggregates
2019. Sixteenth IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI'19), Venice, Italian Republic, April 8-11, 2019. p. 1013 - 1017. DOI : 10.1109/ISBI.2019.8759311.Closed-Form Expression of the Fourier Ring-Correlation for Single-Molecule Localization Microscopy
2019. Sixteenth IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI'19), Venice, Italian Republic, April 8-11, 2019. p. 321 - 324. DOI : 10.1109/ISBI.2019.8759279.SUBDIVIDE AND CONQUER Active Contours and Surfaces for Biomedical Image Segmentation
Lausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-9326.A mobile measurement platform and an image processing procedure for high-resolution aerial thermal imagery of lake surface water temperatures
International Association for Great Lakes Research & European Large Lakes Symposium (ELLS-IAGLR 2018), Evian, France, 23-28 September 2018.Parametric Experimental Study and Design of Experiment Modelling of Sapphire Grinding
Journal of Cleaner Production. 2017. DOI : 10.1016/j.jclepro.2016.09.031.Spline Shape Processing : Representation, Learning, and Modeling
Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-8174.Pancreatic α- and β-Cellular Clocks Have Distinct Molecular Properties and Impact on Islet Hormone Secretion and Gene Expression
Genes & Development. 2017. DOI : 10.1101/gad.290379.116.DeconvolutionLab2: An Open-Source Software for Deconvolution Microscopy
Methods—Image Processing for Biologists. 2017. DOI : 10.1016/j.ymeth.2016.12.015.Investigating Focal Adhesion Substructures by Localization Microscopy
Biophysical Journal. 2017. DOI : 10.1016/j.bpj.2017.09.032.SpotCaliper: Fast Wavelet-Based Spot Detection with Accurate Size Estimation
Bioinformatics. 2016. DOI : 10.1093/bioinformatics/btv728.Super-Resolution Fight Club
Nature Photonics. 2016. DOI : 10.1038/nphoton.2016.22.A Simple, Fast and Low-Cost Method for in situ Monitoring of Topographical Changes and Wear Rate of a Complex Tribo-System Under Mixed Lubrication
Wear—An International Journal on the Science and Technology of Friction, Lubrication and Wear. 2016. DOI : 10.1016/j.wear.2016.06.006.Transforms and Operators for Directional Bioimage Analysis: A Survey
Advances in Anatomy, Embryology and Cell Biology; Springer International Publishing, 2016.On the Continuous Steering of the Scale of Tight Wavelet Frames
SIAM Journal on Imaging Sciences. 2016. DOI : 10.1137/15M1033885.Variational Phase Imaging Using the Transport-of-Intensity Equation
IEEE Transactions on Image Processing. 2016. DOI : 10.1109/TIP.2015.2509249.A Feasability Study of Color Flow Doppler Vectorization for Automated Blood Flow Monitoring
Journal of Clinical Monitoring and Computing. 2016. DOI : 10.1007/s10877-016-9953-2.Quantitative evaluation of software packages for single-molecule localization microscopy
Nature Methods. 2015. DOI : 10.1038/Nmeth.3442.Fast Detection and Refined Scale Estimation Using Complex Isotropic Wavelets
2015. p. 512 - 515. DOI : 10.1109/ISBI.2015.7163923.Analysis of S. pombe SIN protein association to the SPB reveals two genetically separable states of the SIN
Journal Of Cell Science. 2015. DOI : 10.1242/jcs.160150.Phase Retrieval by Using Transport-of-Intensity Equation and Differential Interference Contrast Microscopy
2014. p. 3939 - 3943. DOI : 10.1109/ICIP.2014.7025800.Photobleaching Kinetics and Time-Integrated Emission of Fluorescent Probes in Cellular Membranes
Molecules. 2014. DOI : 10.3390/molecules190811096.Circadian Clock Characteristics Are Altered in Human Thyroid Malignant Nodules
Journal Of Clinical Endocrinology & Metabolism. 2013. DOI : 10.1210/jc.2013-2568.Autonomous and self-sustained circadian oscillators displayed in human islet cells
Diabetologia. 2013. DOI : 10.1007/s00125-012-2779-7.A 2D/3D image analysis system to track fluorescently labeled structures in rod-shaped cells: application to measure spindle pole asymmetry during mitosis
Cell Division. 2013. DOI : 10.1186/1747-1028-8-6.Advanced Image Processing for Biology, and the Open Bio Image Alliance (OBIA)
2013.Benchmarking Image-Processing Algorithms for Biomicroscopy: Reference Datasets and Perspectives
2013.3-D PSF fitting for fluorescence microscopy: implementation and localization application
Journal Of Microscopy. 2013. DOI : 10.1111/j.1365-2818.2012.03675.x.A Psf-Based Approach To Biplane Calibration In 3D Super-Resolution Microscopy
2012. 9th IEEE International Symposium on Biomedical Imaging (ISBI) - From Nano to Macro. p. 1232 - 1235. DOI : 10.1109/ISBI.2012.6235784.Predicting stem cell fate changes by differential cell cycle progression patterns
Development. 2012. DOI : 10.1242/dev.086215.Quantitative fluorescence loss in photobleaching for analysis of protein transport and aggregation
Bmc Bioinformatics. 2012. DOI : 10.1186/1471-2105-13-296.Experimental investigation of collagen waviness and orientation in the arterial adventitia using confocal laser scanning microscopy
Biomechanics and Modeling in Mechanobiology. 2012. DOI : 10.1007/s10237-011-0325-z.Bi-Exponential Edge-Preserving Smoother
Ieee Transactions On Image Processing. 2012. DOI : 10.1109/Tip.2012.2200903.Potential of Ultraviolet Wide-Field Imaging and Multiphoton Microscopy for Analysis of Dehydroergosterol in Cellular Membranes
Microscopy Research And Technique. 2011. DOI : 10.1002/jemt.20878.Fast O(1) Bilateral Filtering Using Trigonometric Range Kernels
IEEE Transactions on Image Processing. 2011. DOI : 10.1109/TIP.2011.2159234.Flow measurements in sewer systems based on image analysis: automatic flow velocity algorithm
Water Science and Technology. 2011. DOI : 10.2166/wst.2011.176.Fast Detection of Cells Using a Continuously Scalable Mexican-Hat-Like Template
2010. 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Rotterdam, NETHERLANDS, Apr 14-17, 2010. p. 1277 - 1280. DOI : 10.1109/ISBI.2010.5490229.Flow measurements in sewer systems based on image analysis: automatic flow velocity algorithm
2010. 7th International conference on sustainable techniques and strategies in urban water management (NOVATECH), Lyon, France, June 27 - July 1st, 2010.Comparison of Deconvolution Software in 3D Microscopy: A User Point of View—Part 1
G.I.T. Imaging & Microscopy. 2010.Flow Measurements in Sewer Systems Based on Image Analysis: Automatic Flow Velocity Algorithm
2010. p. 180 - 189.Comparison of Deconvolution Software: A User Point of View—Part 2
G.I.T. Imaging & Microscopy. 2010.Low-Bond Axisymmetric Drop Shape Analysis for Surface Tension and Contact Angle Measurements of Sessile Drops
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2010. DOI : 10.1016/j.colsurfa.2010.04.040.Multicolor Bleach-Rate Imaging Enlightens in vivo Sterol Transport
Communicative & Integrative Biology. 2010. DOI : 10.4161/cib.3.4.11972.Selective Visualization of Fluorescent Sterols in Caenorhabditis elegans by Bleach-Rate-Based Image Segmentation
Traffic. 2010. DOI : 10.1111/j.1600-0854.2010.01040.x.A software solution for recording circadian oscillator features in time-lapse live cell microscopy
Cell Division. 2010. DOI : 10.1186/1747-1028-5-17.Vision-based system for the control and measurement of wastewater flow rate in sewer systems
Water Science and Technology. 2009. DOI : 10.2166/wst.2009.659.Effect of aging on elastin functionality in human cerebral arteries
Stroke; a journal of cerebral circulation. 2009. DOI : 10.1161/STROKEAHA.108.528091.Phosphorylation does not prompt, nor prevent, the formation of alpha-synuclein toxic species in a rat model of Parkinson's disease
Human Molecular Genetics. 2009. DOI : 10.1093/hmg/ddn417.Circadian gene expression is resilient to large fluctuations in overall transcription rates
The EMBO journal. 2009. DOI : 10.1038/emboj.2008.262.Vision-Based System for the Control and Measurement of Wastewater Flow Rate in Sewer Systems
2009. p. OP03 - 4.Multiresolution Monogenic Signal Analysis Using the Riesz-Laplace Wavelet Transform
Ieee Transactions On Image Processing. 2009. DOI : 10.1109/TIP.2009.2027628.The Marr Wavelet Pyramid and Multiscale Directional Image Analysis
2008.Coupled tomography and distinct-element-method approach to exploring the granular media microstructure in a jamming hourglass
Physical Review E. 2008. DOI : 10.1103/PhysRevE.77.061306.Effect of Ageing on Elastin Functionality in Human Cerebral Arteries
2008. ASME 2008 Summer Bioengineering Conference (SBC'08), Marco Island FL, USA, June 25–29, 2008. p. 959 - 960. DOI : 10.1115/SBC2008-192727.Controlled Exchange of Chromosomal Arms Reveals Principles Driving Telomere Interactions in Yeast
Genome Research. 2008. DOI : 10.1101/gr.6687808.Selective visualization of fluorescent sterols in Caenorhabditis elegans
2008. 49th International Conference on the Bioscience of Lipids, Maastricht, NETHERLANDS, Aug 26-30, 2008. p. S42 - S42. DOI : 10.1016/j.chemphyslip.2008.05.114.Lung Tissue Classification Using Wavelet Frames
2007. p. 6259 - 6262. DOI : 10.1109/IEMBS.2007.4353786.A Snake-Based Approach to Accurate Determination of Both Contact Points and Contact Angles
Colloids And Surfaces A: Physicochemical And Engineering Aspects. 2006. DOI : 10.1016/j.colsurfa.2006.03.008.Automatic Tracking of Individual Fluorescence Particles: Application to the Study of Chromosome Dynamics
IEEE Transactions on Image Processing. 2005. DOI : 10.1109/TIP.2005.852787.Analyse des caractéristiques géométriques d'amas granulaires réels et simulés
2005PixFRET, an ImageJ Plug-in for FRET Calculation That Can Accommodate Variations in Spectral Bleed-throughs
Microscopy Research and Technique. 2005. DOI : 10.1002/jemt.20215.IP-LAB: A Tool to Teach Image Processing Programming in Java—Challenge in Swiss Federal Institute of Technology Lausanne
2005. p. 473 - 474.Image Processing Education
Handbook of Image & Video Processing (Second Edition); Amsterdam, The Netherlands: Elsevier Academic Press, 2005. p. 73 - 95.Extended Depth-of-Focus for Multi-Channel Microscopy Images: A Complex Wavelet Approach
2004. p. 660 - 663. DOI : 10.1109/ISBI.2004.1398624.Extended Depth-of-Field for Color Images in Light Microscopy: Image Fusion and 3D Visualization
Proceedings of the 2004 Annual Meeting of the Swiss Society of Biomedical Engineering (SSBE'04), Zürich, Switzerland, September 2-3, 2004.Complex Wavelets for Extended Depth-of-Field: A New Method for the Fusion of Multichannel Microscopy Images
Microscopy Research and Technique. 2004. DOI : 10.1002/jemt.20092.Teaching Image-Processing Programming in Java
IEEE Signal Processing Magazine. 2003. DOI : 10.1109/MSP.2003.1253553.Automatic Tracking of Particles in Dynamic Fluorescence Microscopy
2003. p. 582 - 586. DOI : 10.1109/ISPA.2003.1296963.Easy Java Programming for Teaching Image Processing
2001. p. 298 - 301. DOI : 10.1109/ICIP.2001.958110.Enseignement et PhD
A co-dirigé les thèses EPFL de
Daniel Andreas Schmitter, Anaïs Badoual, Laurène Donati
Cours
Bioimage informatics
BIO-410
Le cours fournit une complète revue des méthodes, algorithmes et des outils logiciels utilisés en analyse d'images biologiques. Il expose les concepts fondamentaux et les solutions informatiques permettant d'extraire des informations quantitatives à partir d'images multidimensionnelles.
Image processing II
MICRO-512
Traitement d'images avancé par modélisation mathématique. Développement de logiciels de traitement d'images et prototypage dans des cahiers Jupyter ; application à des exemples concrets en vision industrielle et imagerie biomédicale.