Diego Ghezzi

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Professeur assistant tenure track

diego.ghezzi@epfl.ch +41 21 69 33734 http://lne.epfl.ch

EPFL STI IBI-STI LNE
B3 3 246.134 (Campus Biotech batiment B3)
Ch. des Mines 9
CH-1202 Genève

Données administratives

Compétences

Neuro-optoelectronic interfaces, visual prosthesis, optical stimulation, microfabrication, polymers, neuroprosthetics, biocompatibility, visual system, sight restoration, sensory perception, artificial photoreceptors


Parcours professionnel

Researcher Department of Neuroscience and Brain Technologies Istituto Italiano di Tecnologia, Genova, Italy February 2014 - March 2015
Postdoctoral Fellow Laboratory of Prof. Fabio Benfenati Istituto Italiano di Tecnologia, Genova, Italy March 2008 - January 2014

Education

Ph.D. Bioengineering Politecnico di Milano June 27th, 2008
Laurea Biomedical Engineering Politecnico di Milano December 22th, 2004

Publications

Enseignement & Phd

Enseignement

  • Life Sciences Engineering,

Programmes doctoraux

  • Doctoral Program in Microsystems and Microelectronics
  • Doctoral Program in Neuroscience
  • Doctoral Program in Electrical Engineering
  • Doctoral Program in Biotechnology and Bioengineering
  • Doctoral Program in Materials Science and Engineering

Cours

Biomaterials

Ce cours couvre les concepts fondamentaux sur lesquels se basent conception, fonction et mise en oeuvre de biomatériaux de pointe, c'est-à-dire de matériaux conçus à partir de la compréhension à l'échelle moléculaire de l'interaction avec des systèmes bio... goto

Chimie et génie chimique, 2018-2019, Master semestre 2, language : anglais
Chimie et génie chimique, 2018-2019, Master semestre 4, language : anglais
Ingénierie des sciences du vivant, 2018-2019, Master semestre 2, language : anglais
Ingénierie des sciences du vivant, 2018-2019, Master semestre 4, language : anglais
MINEUR, 2018-2019, Semestre printemps, language : anglais
Microtechnique, 2018-2019, Master semestre 2, language : anglais

Materials science for bioengineers

Ce cours vise à introduire aux étudiants la science des matériaux en mettant l¿accent sur ses applications biologiques. goto

Ingénierie des sciences du vivant, 2018-2019, Bachelor semestre 5, language : anglais

Neuroengineering of vision

Le but de ce cours est de fournir les connaissances et les compétences clés nécessaires aux bio-ingénieurs travaillant dans le domaine de la restauration de la vision à l'aide de neuro-prothèses. Dans ce cours, les étudiants travailleront sur un projet li... goto

Ingénierie des sciences du vivant, 2018-2019, Master semestre 1, language : anglais
Ingénierie des sciences du vivant, 2018-2019, Master semestre 3, language : anglais

Scientific literature analysis in bioengineering

Le but est d'apprendre à analyser un article scientifique de manière critique, c'est-à-dire d'étudier le bien fondé des questions scientifiques posées ainsi que des conclusions tirées. goto

Ingénierie des sciences du vivant, 2018-2019, Master semestre 1, language : anglais
Ingénierie des sciences du vivant, 2018-2019, Master semestre 3, language : anglais

Recherche

Retinal Prosthesis

Inspired by intraocular lenses, we have designed a foldable and photovoltaic wide-field epiretinal prosthesis (named POLYRETINA) capable of stimulating wireless retinal ganglion cells. Within a visual angle of 46.3 degrees, POLYRETINA embeds more than 6000 stimulating pixels, it is foldable to allow implantation through a small scleral incision, and it has a hemispherical shape to match the curvature of the eye. We demonstrate that it is not cytotoxic and respects optical and thermal safety standards; accelerated aging shows a lifetime of at least 2 years. POLYRETINA represents a significant progress towards the improvement of both visual acuity and visual field with the same device, a current challenging issue in the field.

Optic Nerve Stimulation

In the last decade, research on vision prosthetics has been focused primarily on retinal prostheses. However, optic nerve represents the preferred point of implantation in order to treat patients not eligible for retinal prostheses (e.g. optic nerve diseases). In our laboratory, we are developing a novel intraneural electrode array (named OpticSELINE) that is effective in inducing the activation of the visual cortex upon electrical stimulation of the optic nerve. The OpticSELINE induces selective cortical activation patterns depending on the stimulating electrode, thus suggesting that it possesses spatial selectivity in fiber stimulation.