The Laboratory of Biomechanical Orthopedics (LBO) is dedicated to the advancement of techniques and technology for patient care in the musculo-skeletal system, through fundamental research, applied research, and teaching
Through biomechanical considerations, Dominique Pioletti's research focus on tissue engineering applications for bone, cartilage and nucleus pulpous. In parallel, new drug delivery solutions for musculo-skeletal tissues are also developed by using mechanical loading as a trigger stimulus for the delivery of drugs.
Dominique Pioletti received his Master in Physics from the Swiss Federal Institute of Technology Lausanne (EPFL) in 1992. He pursued his education in the same Institution and obtained his PhD in biomechanics in 1997. He developed original constitutive laws taking into account viscoelasticity in large deformations. Then he spent two years at UCSD as post-doc fellow acquiring know-how in cell and molecular biology. He was interested in particular to gene expression of bone cells in contact to orthopedic implant. In April 2006, Dominique Pioletti was appointed Assistant Professor tenure-track at the EPFL and is director of the Laboratory of Biomechanical Orthopedics.? His research topics include biomechanics and tissue engineering of musculo-skeletal tissues; mechano-transduction in bone;? development of orthopedic implant as drug delivery system?. Since 2013, he has been promoted to the rank of Associate Professor.
Fields of expertise
- Tissue Engineering
Journal paper and review
|D.P. Pioletti, M.O. Montjovent, P.Y. Zambelli and L. Applegate
Swiss Medical Weekly, 136, 557-560 (2006)
|Bone tissue engineering using fetal cell therapy|