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Administrative data

Dominique Pioletti

dominique.pioletti@epfl.ch https://www.epfl.ch/labs/lbo/

EPFL STI IBI-STI LBO
MED 3 2626 (Bâtiment MED)
Station 9
1015 Lausanne

EPFL STI IBI-GE
MED 3 2626 (Bâtiment MED)
Station 9
1015 Lausanne

EPFL STI IGM-GE
MED 3 2626 (Bâtiment MED)
Station 9
1015 Lausanne

EPFL STI DLL-STI
MED 3 1019 (Bâtiment MED)
Station 9
1015 Lausanne

Expertise

- Orthopedic Biomechanics
- Tissue Engineering
- Mechano-Biology

Current work

Through biomechanical considerations, Dominique Pioletti

Mission

The Laboratory of Biomechanical Orthopedics (LBO) is dedicated to the advancement of techniques and technology for patient care in the musculo-skeletal system, through fundamental research, applied research, and teaching
Dominique Pioletti received his Master in Physics from the Swiss Federal Institute of Technology Lausanne (EPFL) in 1992. He pursued his education in the same Institution and obtained his PhD in biomechanics in 1997. He developed original constitutive laws taking into account viscoelasticity in large deformations. Then he spent two years at UCSD as post-doc fellow acquiring know-how in cell and molecular biology. He was interested in particular to gene expression of bone cells in contact to orthopedic implant. In April 2006, Dominique Pioletti was appointed Assistant Professor tenure-track at the EPFL and is director of the Laboratory of Biomechanical Orthopedics. His research topics include biomechanics and tissue engineering of musculo-skeletal tissues; mechano-transduction in bone; development of orthopedic implant as drug delivery system. Since 2013, he has been promoted to the rank of Associate Professor.

Selected publications

Bone tissue engineering using fetal cell therapy

D.P. Pioletti, M.O. Montjovent, P.Y. Zambelli and L. Applegate
Published in Swiss Medical Weekly, 136, 557-560 (2006) in

Journal paper and review

Teaching & PhD

PhD Students

Alexander Arthur Nottegar, Sruthi Raja, Antoine Reitzel, Ramin Mohammadi, Deniz Cemre Turgut, Léa Pistorius, Mi-Lane Bouchez

Past EPFL PhD Students

Vincent Stadelmann (2008), Philippe Abdel Sayed (2013), Ulrike Kettenberger (2014), Adeliya Latypova (2015), Naser Nasrollahzadeh Mamaghani (2019), Céline Samira Wyss (2021), Peyman Karami (2021), Yanheng Guo (2024), Pezhman Eghbalishamsabadi (2025), Vincent Varanges (2025)

Courses

B1.4 Locomotor system - Anatomy of the locomotor system - (for MED)

UNIL-125

NA

Biomechanics of the musculoskeletal system

ME-482

The basis for a mechanical description of the musculoskeletal system are presented. This description is based on the concepts of solid mechanics, physiology and anatomy of the musculoskeletal system. Concrete examples of the development of implants are also covered.

Engineering of musculoskeletal system and rehabilitation

BIO-687

This course presents today research questions and methods associated to the musculoskeletal system, its pathologies, and treatment.

Experimental methods in biomechanics

ME-380

The aim of this course is to allow the students to become familiar with the basic techniques to measure the mechanical properties of different musculoskeletal tissues or biomaterials used in tissue engineering.