Time-resolved imaging of oxidative stress and cell/tissue oxygenation

V. Huntosova; S. Sokolova; M. Misuth; D. Horvath; G. Wagnieres et al.

2017. 19th IUPAB Congress / 11th EBSA Congress , British Biophys Soc, Edinburgh, SCOTLAND , JUL 16-20, 2017. p. S367-S367.

Modulation of the endogenous production of protoporphyrin IX in a yeast - based model organism

J. Joniova; E. Gerelli; G. Wagnieres

2017. Conference on Optical Biopsy XV - Toward Real-Time Spectroscopic Imaging and Diagnosis , San Francisco, CA , JAN 31-FEB 01, 2017. p. UNSP 1006018.

DOI : 10.1117/12.2256504.

In vivo measurement of the tissue oxygenation by time-resolved luminescence spectroscopy of protoporphyrin IX: Strategies to minimize artefacts associated with photoproducts

E. Gerelli; V. Huntosova; D. Horvath; G. Wagnieres

2017. Conference on Optical Biopsy XV - Toward Real-Time Spectroscopic Imaging and Diagnosis , San Francisco, CA , JAN 31-FEB 01, 2017. p. UNSP 1006016.

DOI : 10.1117/12.2256669.

Negligible interaction of [Ru(Phen) 3 ] 2+ with human serum albumin makes it promising for a reliable in vivo assessment of the tissue oxygenation

D. Belej; Z. Jurasekova; M. Nemergut; G. Wagnieres; D. Jancura et al.

Journal of Inorganic Biochemistry. 2017.

DOI : 10.1016/j.jinorgbio.2017.05.016.

Interstitial fluid pressure: A novel biomarker to monitor photo-induced drug uptake in tumor and normal tissues.

S. Cavin; X. Wang; M. Zellweger; M. Gonzalez; M. Bensimon et al.

Lasers Surg Med. 2017. 2017.

DOI : 10.1002/lsm.22687.

Determination of the radiance of cylindrical light diffusers: design of a one-axis charge-coupled device camera-based goniometer setup

A. Pitzschke; J. Bertholet; B. Lovisa; M. Zellweger; G. Wagnieres

Journal Of Biomedical Optics. 2017.

DOI : 10.1117/1.Jbo.22.3.035004.

Photodynamic therapy for the treatment of atherosclerotic plaque: Lost in translation?

M. Jain; M. Zellweger; G. Wagnieres; H. Van Den Bergh; S. Cook et al.

Cardiovascular Therapeutics. 2017.

DOI : 10.1111/1755-5922.12238.

Measurement of pO2 by luminescence lifetime spectroscopy: A comparative study of the phototoxicity and sensitivity of [Ru(Phen)3]2+ and PdTCPP in vivo

V. Huntosova; E. Gerelli; D. Horvath; G. Wagnieres

Journal of Biophotonics. 2016.

DOI : 10.1002/jbio.201600127.

Optimization and characterization of the endogenous production of protoporphyrin IX in a yeast model

J. Joniová; E. Gerelli; M. Zellweger; G. Wagnières

Journal of biomedical optics. 2016.

DOI : 10.1117/1.JBO.21.12.125008.

Effect of PpIX photoproducts formation on pO2 measurement by time-resolved delayed fluorescence spectroscopy of PpIX in solution and in vivo

V. Huntosova; E. Gerelli; M. Zellweger; G. Wagnières

Journal of photochemistry and photobiology. B, Biology. 2016.

DOI : 10.1016/j.jphotobiol.2016.09.022.

Intra-Arterial Drug and Light Delivery for Photodynamic Therapy Using Visudyne (R): Implication for Atherosclerotic Plaque Treatment

M. Jain; M. Zellweger; A. Frobert; J. Valentin; H. Van Den Bergh et al.

Frontiers In Physiology. 2016.

DOI : 10.3389/fphys.2016.00400.

Use of Water-Soluble Oxygen Sensors to Study the Oxygen Consumption during Photosensitization with Hypericin in Vitro and in Vivo

V. Huntosova; D. Belej; E. Gerelli; P. Miskovsky; G. Wagnieres

2016. 60th Annual Meeting of the Biophysical-Society , Los Angeles, USA , February 27 - March 2, 2016. p. 507A-508A.

Study of the NIR Light Induced Effects on Neuroblastoma N2A Cells with Parkinson's-Like Features

L. Koptasikova; V. Huntosova; E. Gerelli; P. Miskovsky; G. Wagnieres et al.

2016. 60th Annual Meeting of the Biophysical-Society , Los Angeles, USA , February 27 - March 2, 2016. p. 470A-471A.

Review of the role played by the photosensitizer's photobleaching during photodynamic therapy

M. Atif; M. Zellweger; G. Wagnieres

Journal Of Optoelectronics And Advanced Materials. 2016.

Treatment of pleural malignancies by photo-induction combined to systemic chemotherapy: Proof of concept on rodent lung tumors and feasibility study on porcine chest cavities

X. Wang; F. Gronchi; M. Bensimon; T. Mercier; L. A. Decosterd et al.

Lasers In Surgery And Medicine. 2015.

DOI : 10.1002/lsm.22422.

Photobiomodulation Suppresses Alpha-Synuclein-Induced Toxicity in an AAV-Based Rat Genetic Model of Parkinson's Disease

A. Oueslati; B. Lovisa; J. Perrin; G. Wagnières; H. van den Bergh et al.

PloS one. 2015.

DOI : 10.1371/journal.pone.0140880.

Study of the influence of over-the-counter vitamin supplement intake on urine fluorescence to optimize cancer detection by fluorescence cystoscopy

M. Zellweger; C. Martoccia; M. Mengin; C. Iselin; H. Van Den Bergh et al.

Journal Of Biomedical Optics. 2015.

DOI : 10.1117/1.Jbo.20.6.066011.

Optical properties of the deep brain in the red and NIR: changes observed under in-vivo, post-mortem, frozen and formalin-fixated conditions

A. Pitzschke; B. Lovisa; O. Seydoux; M. Zellweger; M. Pfleiderer et al.

2015. Conference on Medical Laser Applications and Laser-Tissue Interactions VII , Munich, GERMANY , JUN 21-23, 2015. p. 954207.

DOI : 10.1117/12.2183687.

Red and NIR light dosimetry in the human deep brain

A. Pitzschke; B. Lovisa; O. Seydoux; M. Zellweger; M. Pfleiderer et al.

Physics in Medicine and Biology. 2015.

DOI : 10.1088/0031-9155/60/7/2921.

Fluence plays a critical role on the subsequent distribution of chemotherapy and tumor growth delay in murine mesothelioma xenografts pre-treated by photodynamic therapy

Y. Wang; X. Wang; M.-A. Le Bitoux; G. Wagnieres; H. Vandenbergh et al.

Lasers in Surgery and Medicine. 2015.

DOI : 10.1002/lsm.22329.

Optical properties of rabbit brain in the red and near-infrared: changes observed under in vivo, postmortem, frozen, and formalin-fixated conditions

A. Pitzschke; B. Lovisa; O. Seydoux; M. Haenggi; M. F. Oertel et al.

Journal Of Biomedical Optics. 2015.

DOI : 10.1117/1.Jbo.20.2.025006.

Detection of Bladder Cancer by Fluorescence Cystoscopy: From Bench to Bedside - the Hexvix Story

G. Wagnières; P. Jichlinski; N. Lange; P. Kucera; H. Van den Bergh

Handbook of Photomedicine. 2014.

DOI : 10.1201/b15582-41.

Endosomes: Guardians Against [Ru(Phen)3]2+ Photo-action In Endothelial Cells During In Vivo pO2 Detection?

V. Huntosova; K. Stroffekova; G. Wagnieres; M. Novotova; Z. Nichtova et al.

Metallomics. 2014.

DOI : 10.1039/C4MT00190G.

Temperature and oxygen-concentration dependence of singlet oxygen production by RuPhen as induced by quasi-continuous excitation

J. Varchola; V. Huntosova; D. Jancura; G. Wagnieres; P. Miskovsky et al.

Photochemical & Photobiological Sciences. 2014.

DOI : 10.1039/C4PP00202D.

Low-Dose Vascular Photodynamic Therapy Decreases Tumor Interstitial Fluid Pressure, which Promotes Liposomal Doxorubicin Distribution in a Murine Sarcoma Metastasis Model

J. Y. Perentes; Y. Wang; X. Wang; E. Abdelnour; M. Gonzalez et al.

Translational oncology. 2014.

DOI : 10.1016/j.tranon.2014.04.010.

In vivo measurement of tissue oxygenation by time-resolved luminescence spectroscopy: advantageous properties of dichlorotris(1, 10-phenanthroline)-ruthenium(II) hydrate

V. Huntosova; S. Gay; P. Nowak-Sliwinska; S. K. Rajendran; M. Zellweger et al.

Journal of Biomedical Optics. 2014.

DOI : 10.1117/1.JBO.19.7.077004.

Optical spectroscopy of the bladder washout fluid to optimize fluorescence cystoscopy with Hexvix

C. Martoccia; M. Zellweger; B. Lovisa; P. Jichlinski; H. Van Den Bergh et al.

Journal of Biomedical Optics. 2014.

DOI : 10.1117/1.JBO.19.9.097002.

Light dose plays a critical role for the distribution of chemotherapy and tumor response in mesothelioma xenografts pre-treated by photodynamic therapy

J. Y. Perentes; X. Wang; Y. Wang; M.-A. Le Bitoux; G. Wagnieres et al.

2014. 101st Annual Congress of the Swiss-Society-of-Surgery . p. 23-23.

Detection of Bladder Cancer by Fluorescence Cystoscopy: From Bench to Bedside - the Hexvix Story

G. Wagnières; P. Jichlinski; N. Lange; P. Kucera; H. van den Bergh

Taylor & Francis.

Study of the stability of the 5-aminolevulinic acid tyrosine ester in aqueous solution

S. Gay; C. Martoccia; M. Zellweger; Q. Wang; G. Wagnières

ARKIVOC - Online Journal of Organic Chemistry. 2014.

DOI : 10.3998/ark.5550190.p008.469.

Correlation between Protoporphyrin IX Fluorescence Intensity, Photobleaching, Pain and Clinical Outcome of Actinic Keratosis Treated by Photodynamic Therapy

F. Piffaretti; M. Zellweger; B. Kasraee; J. Barge; D. Salomon et al.

Dermatology. 2013.

DOI : 10.1159/000353775.

Correlations between photoactivable porphyrins’ fluorescence, erythema and the pain induced by PDT on normal skin using ALA-derivatives

J. Barge; T. Glanzmann; M. Zellweger; D. Salomon; H. Van Den Bergh et al.

Photodiagnosis and Photodynamic Therapy. 2013.

DOI : 10.1016/j.pdpdt.2013.08.005.

Near-Infrared 808 nm Light Boosts Complex IV-Dependent Respiration and Rescues a Parkinson-Related pink1 Model

M. Vos; B. Lovisa; A. Geens; V. A. Morais; G. Wagnières et al.

PLoS ONE. 2013.

DOI : 10.1371/journal.pone.0078562.

Etude préclinique des effets vasculaires induits par la thérapie photodynamique de nouveaux dérivés d’acide 5-aminolevulinique

S. Gay; C. Martoccia; J. Barge; P. Nowak-Sliwinska; G. Wagnières

MRCT CNRS; Biophotonique, optique et diagnostic. 2012.

Reflectance imaging of the human retina at 810 nm does not suffice to optimize the parameters of hydrodynamic rebalancing laser treatment

F. Piffaretti; J.-P. Ballini; R. Perotti; M. Zellweger; E. Vezzola et al.

Journal Of Biomedical Optics. 2012.

DOI : 10.1117/1.Jbo.17.11.116027.

Real-time, in vivo measurement of tissular pO(2) through the delayed fluorescence of endogenous protoporphyrin IX during photodynamic therapy

F. Piffaretti; A. M. Novello; R. S. Kumar; E. Forte; C. Paulou et al.

Journal Of Biomedical Optics. 2012.

DOI : 10.1117/1.Jbo.17.11.115007.

Photoactive sawhorse-type diruthenium tetracarbonyl complexes

J. P. Johnpeter; F. Schmitt; E. Denoyelle-Di-Muro; G. Wagnieres; L. Juillerat-Jeanneret et al.

Inorganica Chimica Acta. 2012.

DOI : 10.1016/j.ica.2012.05.026.

Probing the Interaction Between a Surfactant-Cobalt(III) Complex and Bovine Serum Albumin

R. Senthil Kumar; H. van den Bergh; G. Wagnières

Journal of Solution Chemistry. 2012.

DOI : 10.1007/s10953-012-9800-0.

Angiogenesis inhibition by the maleimide-based small molecule GNX-686

P. Nowak-Sliwinska; M. Storto; T. Cataudella; J.-P. Ballini; R. Gatz et al.

Microvascular Research. 2012.

DOI : 10.1016/j.mvr.2011.10.004.

Study of the pO2-sensitivity of the dendrimeric and free forms of Pd-meso-tetra(4-carboxyphenyl)porphyrin, incorporated or not in chitosan-based nanoparticles

P. Nowak-Sliwinska; P. Käuper; H. van den Bergh; G. Wagnières

Chimia. 2011.

DOI : 10.2533/chimia.2011.691.

Organometallic Ruthenium(II) Arene Compounds with Antiangiogenic Activity

P. Nowak-Sliwinska; V. Beijnum; R. Judy; A. Casini; A. A. Nazarov et al.

Journal of Medicinal Chemistry. 2011.

DOI : 10.1021/jm2002074.

Human serum albumin binding and cytotoxicity studies of surfactant–cobalt(III) complex containing 1,10-phenanthroline ligand

R. S. Kumar; P. Paul; A. Riyasdeen; G. Wagnières; H. van den Bergh et al.

Colloids and Surfaces B: Biointerfaces. 2011.

DOI : 10.1016/j.colsurfb.2011.03.012.

Low dose endoluminal photodynamic therapy improves murine T cell-mediated colitis

L. Favre; F. Borle; D. Velin; D. Bachmann; H. Bouzourene et al.

Endoscopy. 2011.

DOI : 10.1055/s-0030-1256382.

Solution for diagnosing or treating tissue pathology

A. Marti; N. Lange; M. Zellweger; G. Wagnieres; H. Van Den Bergh et al.

2010.

Errata: Processing of Fluorescence Angiograms for the Quantification of Vascular Effects Induced by Anti-angiogenic Agents in the CAM model (vol 79, pg 21, 2010)

P. Nowak-Sliwinska; J.-P. Ballini; G. Wagnières; H. van den Bergh

Microvascular Research. 2010.

DOI : 10.1016/j.mvr.2010.01.009.

Chitosan-based nanogels for selective delivery of photosensitizers to macrophages and improved retention in and therapy of articular joints

F. Schmitt; L. Lagopoulos; P. Kaeuper; N. Rossi; N. Busso et al.

Journal Of Controlled Release. 2010.

DOI : 10.1016/j.jconrel.2010.02.008.

In vitro and in vivo photocytotoxicity of boron dipyrromethene derivatives for photodynamic therapy

S. H. Lim; C. Thivierge; P. Nowak-Sliwinska; J. Han; H. van den Bergh et al.

Journal of Medicinal Chemistry. 2010.

DOI : 10.1021/jm901823u.

The Neovessel Occlusion Efficacy of 15(1)-hydroxypurpurin-7-lactone dimethyl ester induced with photodynamic therapy

S. H. Lim; P. Nowak-Sliwinska; F. A. Kamarulzaman; H. Van Den Bergh; G. Wagnières et al.

Photochemistry and Photobiology. 2010.

DOI : 10.1111/j.1751-1097.2009.00684.x.

Angiostasis-induced vascular normalization can improve photodynamic therapy

P. Nowak-Sliwinska; G. Wagnières; H. van den Bergh; A. W. Griffioen

Cellular and Molecular Life Sciences. 2010.

DOI : 10.1007/s00018-010-0294-x.

Processing of fluorescence angiograms for the quantification of vascular effects induced by anti-angiogenic agents in the CAM model

P. Nowak-Sliwinska; J.-P. Ballini; G. Wagnières; H. Van Den Bergh

Microvascular Research. 2010.

DOI : 10.1016/j.mvr.2009.10.004.

Photodynamic Therapy Selectively Enhances Liposomal Doxorubicin Uptake in Sarcoma Tumors to Rodent Lungs

C. Cheng; E. Debefve; A. Haouala; S. Andrejevic-Blant; T. Krueger et al.

Lasers In Surgery And Medicine. 2010.

DOI : 10.1002/lsm.20912.

Fluorescence of the bladder washout fluid following cystoscopy: a preliminary study

B. Lovisa; A. M. Novello; P. Jichlinski; H. van den Bergh; G. Wagnieres

2010. Conference on Photonic Therapeutics and Diagnostics VI , San Francisco, CA , Jan 23-25, 2010. p. -.

DOI : 10.1117/12.842100.

Pioneers in biomedical optics: Special section honoring professor Tayyaba Hasan

B. W. Pogue; G. A. Wagnieres; L. D. Lilge

Journal of Biomedical Optics. 2010.

DOI : 10.1117/1.3492580.

High-magnification vascular imaging to reject false-positive sites in situ during Hexvix® fluorescence cystoscopy

B. Lovisa; P. Jichlinski; B.-C. Weber; D. Aymon; H. van den Bergh et al.

Journal of Biomedical Optics. 2010.

DOI : 10.1117/1.3484257.

Development of Minimally-Invasive Optical Methods to Individualize the Doses Used for Therapeutic Applications of Light

F. Piffaretti / G. Wagnières (Dir.)

Lausanne, EPFL, 2010.

DOI : 10.5075/epfl-thesis-4831.

Endoscopic Fluorescence Imaging

B. Lovisa / G. Wagnières (Dir.)

Lausanne, EPFL, 2010.

DOI : 10.5075/epfl-thesis-4797.

Bladder cancer detection by fluorescence imaging with Hexvix®: Analysis and processing of images obtained during high magnification cystoscopy

B. Lovisa; P. Jichlinski; D. Aymon; B.-C. Weber; H. van den Bergh et al.

2009. p. 1-6.

DOI : 10.1117/12.822971.

In vitro and in vivo studies of new photoluminescent oxygen sensors for non-invasive intravascular pO 2 measurements

P. Nowak-Sliwinska; E. Forte; H. Van Den Bergh; G. Wagnières

2009. p. 73806N.

DOI : 10.1117/12.822989.

Vascular effects induced by anti-VEGF agents in the CAM model: Effect of the DMSO

P. Nowak-Sliwinska; J.-P. Ballini; H. Van Den Bergh; G. Wagnières

2009. p. null.

DOI : 10.1117/12.822967.

In vivo time-resolved spectroscopy of the human bronchial early cancer autofluorescence

P. Uehlinger; T. Gabrecht; T. Glanzmann; J.-P. Ballini; A. Radu et al.

Journal of biomedical optics. 2009.

DOI : 10.1117/1.3088100.

Detection of early bladder carcinoma by fluorescence cystoscopy with Hexvix: optical characterization of a high magnification cystoscope

B. Lovisa; P. Jichlinski; D. Aymon; B.-C. Weber; H. Van Den Bergh et al.

2009. Photonic Therapeutics and Diagnostics V , San Jose, CA, USA . p. 716118-716118-6.

DOI : 10.1117/12.809195.

Bladder cancer detection by fluorescence imaging with Hexvix®: Analysis and processing of images obtained during high magnification cystoscopy

B. Lovisa; P. Jichlinski; D. Aymon; B.-C. Weber; H. van den Bergh et al.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2009.

DOI : 10.1117/12.822971.

Photodynamic Hair Re-Growth Inhibition With Ala Derivatives

J. Barge; T. Glanzmann; D. Salomon; H. van den Bergh; G. Wagnières

2009. 29th Annual Conference of the American-Society-for-Laser-Medicine and Surgery , National Harbor, MD , Apr 01-05, 2009. p. 38-38.

Autofluorescence bronchoscopy: quantification of inter-patient variations of fluorescence intensity

T. Gabrecht; B. Lovisa; H. van den Bergh; G. Wagnières

Lasers in medical science. 2009.

DOI : 10.1007/s10103-007-0518-y.

Assessment of a sheep animal model to optimize photodynamic therapy with Foscan in the esophague

T. Glanzmann; M. Zellweger; F. Borle; R. Conde; A. Radu et al.

Lasers In Surgery And Medicine. 2009.

DOI : 10.1002/lsm.20844.

Improvement of the specificity of cancer detection by autofluorescence imaging in the tracheo-bronchial tree using backscattered violet light

T. Gabrecht; A. Radu; P. Grosjean; B. Weber; G. Reichle et al.

Photodiagnosis and photodynamic therapy. 2008.

DOI : 10.1016/j.pdpdt.2008.01.005.

Autofluorescence detection of tumors in the human lung - spectroscopical measurements in situ, in an in vivo model and in vitro

D. Hüttenberger; T. Gabrecht; G. Wagnières; B. Weber; A. Linder et al.

Photodiagnosis and photodynamic therapy. 2008.

DOI : 10.1016/j.pdpdt.2008.05.002.

Fluorescence cystoscopy: Perspective in clinical practice and research

P. Jichlinski; B. Lovisa; C. Erling; D. Aymon; H. van den Bergh et al.

Der Urologe. Ausg. A. 2008.

DOI : 10.1007/s00120-008-1778-2.

Video monitoring of neovessel occlusion induced by photodynamic therapy with verteporfin (Visudyne(r)), in the CAM model

E. Debefve; B. Pegaz; H. van den Bergh; G. Wagnières; N. Lange et al.

Angiogenesis. 2008.

DOI : 10.1007/s10456-008-9106-4.

Comparison of ALA- and ALA hexyl-ester-induced PpIX depth distribution in human skin carcinoma

N. Dögnitz; D. Salomon; M. Zellweger; J.-P. Ballini; T. Gabrecht et al.

Journal of photochemistry and photobiology.B.Biology. 2008.

DOI : 10.1016/j.jphotobiol.2008.07.012.

Glycoside esters of 5-aminolevulinic acid for photodynamic therapy of cancer

R. Vallinayagam; F. Schmitt; J. Barge; G. Wagnières; V. Wenger et al.

Bioconjugate Chemistry. 2008.

DOI : 10.1021/bc700324r.

Detection of early bladder carcinoma by fluorescence cystoscopy with Hexvix(R): Improvement of the specificity by microcystoscopy

B. Lovisa; P. Jichlinski; D. Aymon; H. Van Den Bergh; G. Wagnières

2008. p. 684218.

DOI : 10.1117/12.763353.

Detection of early bronchial cancer by autofluorescence: Results in patients with H&N cancer

T. Gabrecht; A. Radu; M. Zellweger; B. Lovisa; D. Goujon et al.

2007. p. OC1-OC8.

Correlations between tissular effects, PPIX fluorescence and the pain induced by PDT on normal skin

D. Salomon; J. Barges; T. Glanzmann; G. Wagnieres

2007. 37th Annual Meeting of the European-Society-for-Dermatological-Research , Zurich, SWITZERLAND , Sep 05-08, 2007. p. S47-S47.

Design of an endoscopic optical reference to be used for autofluorescence bronchoscopy with a commercially available diagnostic autofluorescence endoscopy (DAFE) system

T. Gabrecht; B. Lovisa; F. Borle; G. Wagnières

Physics in medicine and biology. 2007.

DOI : 10.1088/0031-9155/52/8/N02.

Blue-violet excited autofluorescence spectroscopy and imaging of normal and cancerous human bronchial tissue after formalin fixation

T. Gabrecht; S. Andrejevic-Blant; G. Wagnières

Photochemistry and photobiology. 2007.

DOI : 10.1562/2006-03-20-RA-852.

Design of a light delivery system for the photodynamic treatment of the Crohn's disease

T. Gabrecht; F. Borle; H. Van Den Bergh; P. Michetti; M.-A. Ortner et al.

2007.

DOI : 10.1117/12.728477.

Autofluorescence bronchoscopy: Clinical experience with an optimized system in head and neck cancer patients

T. Gabrecht; A. Radu; M. Zellweger; B. Lovisa; D. Goujon et al.

Medical Laser Application. 2007.

DOI : 10.1016/j.mla.2007.09.003.

Optimized autofluorescence bronchoscopy using additional backscattered red light

T. Gabrecht; T. Glanzmann; L. Freitag; B.-C. Weber; H. van den Bergh et al.

Journal of biomedical optics. 2007.

DOI : 10.1117/1.2811952.

Improvement of the Contrast in Cancer Detection by Autofluorescence Bronchoscopy using a narrow spectral violet Excitation: A preliminary study

B. Lovisa; T. Gabrecht; S. Andrejevic; P. Grosjean; A. Radu et al.

Biomedical Signal Processing and Control. 2007.

DOI : 10.1016/j.bspc.2007.07.004.

Detection of early bronchial cancer by autofluorescence: first clinical results with an improved system

M. Zellweger; D. Goujon; A. Radu; P. Grosjean; T. Stepinac et al.

2007.

Photodynamic therapy as a novel therapeutic approach for the treatment of Crohn's disease

L. Favre; D. Velin; F. Borle; D. Bachmann; S. Schreiber et al.

Gastroenterology. 2006.

Improvement of the contrast in cancer detection by autofluorescence bronchoscopy using a narrow spectral violet excitation: A preliminary study

B. Lovisa; T. Gabrecht; S. Andrejevic; P. Grosjean; A. Radu et al.

2006. p. 17-21.

Preclinical comparison of mTHPC and verteporfin for intracavitary photodynamic therapy of malignant pleural mesothelioma

I. Opitz; T. Krueger; Y. Pan; H.-J. Altermatt; G. Wagnières et al.

European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes. 2006.

DOI : 10.1159/000094028.

Photothrombic activity of m-THPC-loaded liposomal formulations: pre-clinical assessment on chick chorioallantoic membrane model

B. Pegaz; E. Debefve; J.-P. Ballini; G. Wagnières; S. Spaniol et al.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2006.

DOI : 10.1016/j.ejps.2006.01.008.

On the role of iron and one of its chelating agents in the production of protoporphyrin IX generated by 5-aminolevulinic acid and its hexyl ester derivative tested on an epidermal equivalent of human skin

P. Uehlinger; J. P. Ballini; H. van den Bergh; G. Wagnieres

Photochemistry and Photobiology. 2006.

DOI : 10.1562/2005-12-04-RA-745.

Clinical fluorescence spectroscopy and imaging for the detection of early carcinoma by autofluorescence bronchoscopy and the study of the protoporphyrin IX pharmacokinetics in the endometrium

T. Gabrecht / G. Wagnières (Dir.)

Lausanne, EPFL, 2006.

DOI : 10.5075/epfl-thesis-3537.

Influence of the excitation wavelength on the Tumor-to-Healthy Contrast in Autofluorescence Bronchoscopy - A Comprehensive Study

T. Gabrecht; P. Uehlinger; S. Andrejevic; P. Grosjean; A. Radu et al.

2005. p. 1-6.

Autofluorescence detection of tumors in the human lung -comparison between in-vivo and in vitro measurements

D. Hüttenberger; T. Gabrecht; G. Wagnières; B. Weber; A. Linder et al.

2005. p. 1-9.

Influence of the menstrual cycle on aminolevulinic acid induced protoporphyrin IX fluorescence in the endometrium: in vivo study

A. Degen; T. Gabrecht; G. Wagnieres; R. Caduff; B. Imthurn et al.

Lasers in Surgery and Medicine. 2005.

DOI : 10.1002/lsm.20139.

Preclinical evaluation of a novel water-soluble chlorin E-6 derivative (BLC 1010) as photosensitizer for the closure of the neovessels

B. Pegaz; E. Debefve; F. Borle; J. P. Ballini; G. Wagnieres et al.

Photochemistry and Photobiology. 2005.

DOI : 10.1562/2005-02-23-RA-448.

Photodynamic therapy and endoscopic mucosal resection as minimally invasive approaches for the treatment of early esophageal tumors: Pre-clinical and clinical experience in Lausanne

A. Radu; P. Grosjean; Y. Jaquet; R. Pilloud; G. Wagnières et al.

Photodiagnosis and Photodynamic Therapy . 2005.

DOI : 10.1016/S1572-1000(05)00035-9.

Light-induced retinal vascular damage by Pd-porphyrin luminescent oxygen probes

T. K. Stepinac; S. K. Chamot; E. Rungger-Brandle; P. Ferrez; J. L. Munoz et al.

Investigative Ophthalmology & Visual Science. 2005.

DOI : 10.1167/iovs.04-0500.

Méthodes optiques de mesure de la concentration d'oxygène tissulaire pour la photothérapie dynamique

G. Wagnières

Photoniques. 2004.

Time-dependent hexaminolaevulinate induced protoporphyrin IX distribution after topical application in patients with cervical intraepithelial neoplasia: A fluorescence microscopy study

S. Andrejevic-Blant; A. Major; F. Ludicke; J. P. Ballini; G. Wagnieres et al.

Lasers in Surgery and Medicine. 2004.

DOI : 10.1002/lsm.20095.

Photodynamic endometrial ablation for the treatment of dysfunctional uterine bleeding: A preliminary report

A. F. Degen; T. A. Gabrecht; L. Mosimann; M. K. Fehr; R. Hornung et al.

Lasers in Surgery and Medicine. 2004.

DOI : 10.1002/lsm.10244.

Optimalisation de la photothérapie dynamique et de la photodétection de cancers précoces par spectroscopie résolue en temps de luminophores endogènes et exogènes

P. Uehlinger / G. Wagnières (Dir.)

Lausanne, EPFL, 2004.

DOI : 10.5075/epfl-thesis-3149.

Method for hair removal

H. van den Bergh; G. Wagnieres; N. Lange; N. Doegnitz; D. Salomon

2003.

Optimization of the spectral design used to detect early carcinoma in the human tracheo-bronchial tree by autofluorescence imaging

T. Gabrecht; T. Glanzmann; L. Freitag; P. Grosjean; B. Weber et al.

2003. p. 1-7.

On the influence of the instillation time on the results of HAL (Hexvix®) fluorescence detection of superficial bladder cancer

P. Jichlinski; D. Aymon; G. Wagnières; A. Marti; N. Lange et al.

2003. p. 272-277.

DOI : 10.1117/12.502218.

Photodynamic endometrial ablation: Morphological study

P. Wyss; R. Caduff; Y. Tadir; A. Degen; G. Wagnières et al.

Lasers in Surgery and Medicine. 2003.

DOI : 10.1002/lsm.10163.

Lung cancer Imaging by autofluorescence bronchoscopy

G. Wagnières; A. Mc Williams; S. Lam

Handbook of Biomedical Fluorescence; Marcel Dekker Inc., 2003. p. 361-396.

In vivo autofluorescence imaging of early cancers in the human tracheobronchial tree with a spectrally optimized system

D. Goujon; M. Zellweger; A. Radu; P. Grosjean; B.-C. Weber et al.

Journal of biomedical optics. 2003.

DOI : 10.1117/1.1528594.

Selectivity of the photosensitiser Tookad((R)) for photodynamic therapy evaluated in the Syrian golden hamster cheek pouch tumour model

F. Borle; A. Radu; C. Fontolliet; H. van den Bergh; P. Monnier et al.

British Journal of Cancer. 2003.

DOI : 10.1038/sj.bjc.6601428.

Evaluation of the photosensitizer Tookad (R) for photodynamic therapy on the Syrian golden hamster cheek pouch model: Light dose, drug dose and drug-light interval effects

F. Borle; A. Radu; P. Monnier; H. van den Bergh; G. Wagnieres

Photochemistry and Photobiology. 2003.

DOI : 10.1562/0031-8655(2003)078<0377:EOTPTF>2.0.CO;2.

Photodynamic diagnosis of ovarian cancer using hexaminolaevulinate: a preclinical study

F. Ludicke; T. Gabrecht; N. Lange; G. Wagnieres; H. van den Bergh et al.

British Journal of Cancer. 2003.

DOI : 10.1038/sj.bjc.6600958.

Mucosal ablation with photodynamic therapy in the esophagus: optimization of light dosimetry in the sheep model

A. Radu; R. Conde; C. Fontolliet; G. Wagnieres; H. Van den Bergh et al.

Gastrointestinal Endoscopy. 2003.

DOI : 10.1016/S0016-5107(03)70027-3.

Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid

T. Stepinac; C. Felley; P. Jornod; N. Lange; T. Gabrecht et al.

Endoscopy. 2003.

Caractérisation de tissus biologiques in vivo par imagerie de l'intensité ou du temps de vie de luminescence

T. Stepinac / G. Wagnières (Dir.)

Lausanne, EPFL, 2003.

DOI : 10.5075/epfl-thesis-2645.

In vivo fluorescence spectroscopy to optimize the detection of early bronchial carcinoma by autofluorescence imaging

G. Wagnières; M. Zellweger; P. Grosjean; D. Goujon; R. Conde et al.

2002. p. 1-12.

DOI : 10.1117/12.466647.

Uptake and localisation of mTHPC (Foscan (R)) and its C-14-labelled form in normal and tumour tissues of the hamster squamous cell carcinoma model: a comparative study

S. A. Blant; T. M. Glanzmann; J. P. Ballini; G. Wagnieres; H. van den Bergh et al.

British Journal of Cancer. 2002.

DOI : 10.1038/sj.bjc.6600651.

Optimization of the diameter of a radial irradiation device for photodynamic therapy in the esophagus

T. Stepinac; P. Grosjean; A. Woodtli; P. Monnier; H. van den Bergh et al.

Endoscopy. 2002.

DOI : 10.1055/s-2002-25280.

Photoeradication of Helicobacter pylori using 5-aminolevulinic acid: Preliminary human studies

C. H. Wilder-Smith; P. Wilder-Smith; P. Grosjean; H. van den Bergh; A. Woodtli et al.

Lasers in Surgery and Medicine. 2002.

DOI : 10.1002/lsm.10066.

Time-resolved autofluorescence spectroscopy of the bronchial mucosa for the detection of early cancer: Clinical results

T. M. Glanzmann; P. Uehlinger; J.-P. Ballini; A. Radu; T. Gabrecht et al.

2001. p. 199-209.

DOI : 10.1117/12.447136.

First report on hexyl-ester aminolevulinic acid (h-ALA) induced fluorescence cystoscopy in superficial bladder cancer

P. Jichlinski; A. Marti; L. Guillou; N. Lange; G. Wagnières

European Urology. 2001.

Detection of early bronchial carcinoma by imaging of the tissue autofluorescence

D. Goujon; T. Glanzmann; T. Gabrecht; M. Zellweger; A. Radu et al.

2001. p. 131-138.

DOI : 10.1117/12.447129.

A new drug-screening procedure for photosensitizing agents used in photodynamic therapy for CNV

N. Lange; J. P. Ballini; G. Wagnieres; H. van den Bergh

Investigative ophthalmology & visual science. 2001.

Time-Resolved Autofluorescence Spectroscopy of the Bronchial Mucosa for the Detection of Early Cancer: Ex vivo and Clinical Results

P. Uehlinger; T. Glanzmann; J. Ballini; A. Radu; T. Gabrecht et al.

Proceedings SPIE. 2001.

DOI : 10.1117/12.447136.

Localization of tetra(m-hydroxyphenyl)chlorin (Foscan) in human healthy tissues and squamous cell carcinomas of the upper aero-digestive tract, the esophagus and the bronchi: a fluorescence microscopy study

S. A. Blant; P. Grosjean; J. P. Ballini; G. Wagnieres; H. van den Bergh et al.

Journal of Photochemistry and Photobiology B-Biology. 2001.

DOI : 10.1016/S1011-1344(01)00148-8.

Absolute autofluorescence spectra of human healthy, metaplastic, and early cancerous bronchial tissue in vivo

M. Zellweger; D. Goujon; R. Conde; M. Forrer; H. van den Bergh et al.

Applied optics. 2001.

DOI : 10.1364/AO.40.003784.

In vivo autofluorescence spectroscopy of human bronchial tissue to optimize the detection and imaging of early cancers

M. Zellweger; P. Grosjean; D. Goujon; P. Monnier; H. van den Bergh et al.

Journal of biomedical optics. 2001.

DOI : 10.1117/1.1332774.

5-Aminolevulinic acid and its derivatives: physical chemical properties and protoporphyrin IX formation in cultured cells

P. Uehlinger; M. Zellweger; G. Wagnières; L. Juillerat-Jeanneret; H. van den Bergh et al.

Journal of photochemistry and photobiology. B, Biology. 2000.

DOI : 10.1016/S1011-1344(99)00159-1.

Photodynamic therapy of early squamous cell cancers of the esophagus

A. Radu; G. Wagnières; H. van den Bergh; P. Monnier

Gastrointestinal endoscopy clinics of North America. 2000.

Time-dependent biodistribution of tetra(m-hydroxyphenyl)chlorin and benzoporphyrin derivative monoacid ring A in the hamster model: comparative fluorescence microscopy study

S. Andrejevic Blant; J. P. Ballini; H. van den Bergh; C. Fontolliet; G. Wagnières et al.

Photochemistry and photobiology. 2000.

DOI : 10.1562/0031-8655(2000)0710333TDBOTM2.0.CO2.

A light distributor for photodynamic endometrial ablation

R. Bays; A. Woodtli; L. Mosimann; P. Wyss; G. Wagnières et al.

Photomedicine in Gynecology and Reproduction; Basel: Karger, 2000. p. 243-245.

Pharmacokinetics and pharmacodynamics of tetra(m-hydroxyphenyl)chlorin in the hamster cheek pouch tumor model: comparison with clinical measurements

T. Glanzmann; M. Forrer; S. Andrejevic Blant; A. Woodtli; P. Grosjean et al.

Journal of Photochemistry and Photobiology B-Biology. 2000.

DOI : 10.1016/S1011-1344(00)00069-5.

Fluorescence pharmacokinetics of Lutetium Texaphyrin (PCI-0123, Lu-Tex) in the skin and in healthy and tumoral hamster cheek-pouch mucosa

M. Zellweger; A. Radu; P. Monnier; H. van den Bergh; G. Wagnières

Journal of Photochemistry and Photobiology B: Biology. 2000.

DOI : 10.1016/S1011-1344(00)00027-0.

Fluorescence spectroscopy of exogenous, exogenously-induced and endogenous fluorophores for the photodetection and photodynamic therapy of cancer

M. Zellweger / G. Wagnières (Dir.)

Lausanne, EPFL, 2000.

DOI : 10.5075/epfl-thesis-2126.

Noninvasive determination of the optical properties of two-layered turbid media from time-resolved reflectance measurements

A. Kienle; T. Glanzmann; G. Wagnieres; H. van den Bergh

1999. p. 20-27.

DOI : 10.1117/12.336945.

Frequency-Domain Fluorescence Lifetime Imaging (FLIM) For Real-Time Endoscopic Tissue Characterization

G. Wagnières; T. Stepinac; J. Miseret; H. van den Bergh

1999. Biomedical Topical Meeting , Munich, Germany , June 14, 1999. p. 477-479.

Stability of the fluorescence measurement of Foscan in the normal human oral cavity as an indicator of its content in early cancers of the esophagus and the bronchi

M. Zellweger; P. Grosjean; P. Monnier; H. Van Den Bergh; G. Wagnieres

Photochemistry and Photobiology. 1999.

DOI : 10.1111/j.1751-1097.1999.tb03335.x.

Photoeradication of Helicobacter pylori in humans: Phase 1 study

C. H. Wilder-Smith; P. Grosjean; G. Wagnieres; P. Wilder-Smith; G. Dorta et al.

American Gastroenterology Association Annual meeting. 1999.

Solution for diagnosing or treating tissue pathologies

A. Marti; N. Lange; M. Zellweger; G. Wagnieres; H. Van Den Bergh et al.

1999.

Time-resolved spectrofluorometer for clinical tissue characterization during endoscopy

T. Glanzmann; J.-P. Ballini; H. van den Bergh; G. Wagnieres

Review of Scientific Instruments. 1999.

DOI : 10.1063/1.1150038.

In vivo fluence rate and fractionation effects on tumor response and photobleaching: Photodynamic therapy with two photosensitizers in an orthotopic rat tumor model

S. Iinuma; K. T. Schomacker; G. Wagnieres; M. Rajadhyaksha; M. Bamberg et al.

Cancer Research. 1999.

Photodetection of early human bladder cancer based on the fluorescence of 5-aminolaevulinic acid hexylester-induced protoporphyrin IX: a pilot study

N. Lange; P. Jichlinski; M. Zellweger; M. Forrer; A. Marti et al.

British Journal of Cancer. 1999.

DOI : 10.1038/sj.bjc.6690338.

Instrumentation for real-time fluorescence lifetime imaging in endoscopy

J. Mizeret; T. Stepinac; M. Hansroul; A. Studzinski; H. van den Bergh et al.

Review of Scientific Instruments. 1999.

DOI : 10.1063/1.1150132.

Photodynamic therapy for 101 early cancers of the upper aerodigestive tract, the esophagus, and the bronchi: a single-institution experience

A. Radu; P. Grosjean; C. Fontolliet; G. Wagnières; A. Woodtli et al.

Diagnostic and therapeutic endoscopy. 1999.

DOI : 10.1155/DTE.5.145.

Dependence of time and space resolved reflectance on the anisotropy factor g and on the shape of the phase function

S. Avrillier; B. Gelebart; J.-M. Tualle; E. Tinet; G. Wagnieres

1998. Advances in Optical Imaging and Photon Migration , Orlando, Florida, USA , March 8, 1998.

Long circulating half-life and high tumor selectivity of the photosensitizer meta-tetrahydroxyphenylchlorin conjugated to polyethylene glycol in nude mice grafted with a human colon carcinoma

P. Westermann; T. Gianzmann; S. Andrejevic; D. R. Braichotte; M. Forrer et al.

International Journal of Cancer. 1998.

DOI : 10.1002/(SICI)1097-0215(19980610)76:6<842::AID-IJC13>3.0.CO;2-4.

Clinical evaluation of the cutaneous phototoxicity of 5, 10, 15, 20-tetra (m-hydroxyphenyl)chlorin

G. Wagnieres; C. Hadjur; P. Grosjean; D. Braichotte; J.-F. Savary et al.

Journal of Photochemistry and Photobiology a. 1998.

DOI : 10.1111/j.1751-1097.1998.tb09696.x.

Noninvasive determination of the optical properties of two-layered turbid media

A. Kienle; M. S. Patterson; N. Dognitz; R. Bays; G. Wagnieres et al.

Applied Optics. 1998.

DOI : 10.1364/AO.37.000779.

Investigation of two-layered turbid media with time-resolved reflectance

A. Kienle; T. Glanzmann; G. Wagnieres; H. van den Bergh

Applied Optics. 1998.

DOI : 10.1364/AO.37.006852.

Clinical photodynamic therapy for superficial cancer in the esophagus and the bronchi: 514 nm compared with 630 nm light irradiation after sensitization with Photofrin II

P. Grosjean; G. Wagnieres; C. Fontolliet; H. Van Den Bergh; P. Monnier

British Journal of Cancer. 1998.

Pharmacokinetics of tetra(m-hydroxyphenyl)chlorin in human plasma and individualized light dosimetry in photodynamic therapy

T. Glanzmann; C. Hadjur; M. Zellweger; P. Grosjean; M. Forrer et al.

Photochemistry and Photobiology. 1998.

DOI : 10.1111/j.1751-1097.1998.tb09099.x.

Interstitial photodynamic therapy with tetra(m-hydroxyphenyl)chlorin: tumor versus striated muscle damage

S. Andrejevic-Blant; A. Woodtli; G. Wagnieres; C. Fontolliet; H. Van Den Bergh et al.

International Journal of Radiation Oncology Biology Physics. 1998.

DOI : 10.1016/S0360-3016(98)00221-1.

Determination of tissue optical properties by steady-state spatial frequency-domain reflectometry

N. Dognitz; G. Wagnières

Lasers in Medical Science. 1998.

DOI : 10.1007/BF00592960.

Spectroscopic studies of photobleaching and photoproduct formation of meta(tetrahydroxyphenyl)chlorin (m-THPC) used in photodynamic therapy. The production of singlet oxygen by m-THPC

C. Hadjur; N. Lange; J. Rebstein; P. Monnier; H. van den Bergh et al.

Journal of Photochemistry and Photobiology B: Biology. 1998.

DOI : 10.1016/S1011-1344(98)00177-8.

Photodynamic therapy of early squamous cell carcinomas of the esophagus: A review of 31 cases

J. F. Savary; P. Grosjean; P. Monnier; C. Fontolliet; G. Wagnieres et al.

Endoscopy. 1998.

In vivo fluorescence spectroscopy and imaging for oncological applications

G. Wagnières; W. M. Star; B. C. Wilson

Photochemistry and Photobiology. 1998.

Clinical imaging fluorescence apparatus for the endoscopic photodetection of early cancers by use of Photofrin II

G. A. Wagnières; A. P. Studzinski; D. R. Braichotte; P. Monnier; C. Depeursinge et al.

Applied Optics. 1997.

DOI : 10.1364/AO.36.005608.

Fluorescence photodetection of urothelial neoplastic foci in superficial bladder cancer

P. Jichlinski; M. Forrer; J. C. Mizeret; D. Braichotte; G. Zimmer et al.

1997. p. 470-474.

DOI : 10.1117/12.275078.

Determination of the absorption and reduced scattering coefficients of human skin and bladder by spatial frequency domain reflectometry

N. Dögnitz; G. Wagnières; A. Kienle; H. Van den Bergh

1997. p. 102-109.

DOI : 10.1117/12.297883.

An endoscopic fluorescence imaging system for simultaneous visual examination and photodetection of cancers

G. Wagnières; A. Studzinski; H. van den Bergh; E. Hubert

Review of Scientific Instruments. 1997.

DOI : 10.1063/1.1147811.

Photodynamic therapy for early squamous cell carcinomas of the esophagus, bronchi, and mouth with m-tetra(hydroxyphenyl) chlorin

J.-F. Savary; P. Monnier; C. Fontolliet; J. Mizeret; G. Wagnières et al.

Archives of Otolaryngology - Head and Neck Surgery. 1997.

EPR and spectrophotometric studies of free radicals (O2.-, .OH, BPD-MA.-) and singlet oxygen (1O2) generated by irradiation of benzoporphyrin derivative monoacid ring A

C. Hadjur; G. Wagnieres; P. Monnier; H. Van Den Bergh

Photochemistry and Photobiology. 1997.

DOI : 10.1111/j.1751-1097.1997.tb01929.x.

Photodynamic therapy of early squamous cell carcinoma with tetra(m-hydroxyphenyl)chlorin: optimal drug-light interval

S. Andrejevic-Blant; C. Hadjur; J. P. Ballini; G. Wagnières; C. Fontolliet et al.

British journal of cancer. 1997.

Light dosimetry for photodynamic therapy in the esophagus

R. Bays; G. Wagnieres; D. Robert; D. Braichotte; J. F. Savary et al.

Lasers in Surgery and Medicine. 1997.

DOI : 10.1002/(SICI)1096-9101(1997)20:3<290::AID-LSM8>3.0.CO;2-L.

Three-dimensional optical phantom and its application in photodynamic therapy

R. Bays; G. Wagnieres; D. Robert; J. F. Theumann; A. Vitkin et al.

Lasers in Surgery and Medicine. 1997.

DOI : 10.1002/(SICI)1096-9101(1997)21:3<227::AID-LSM2>3.0.CO;2-S.

Wavelength-dependent effect of tetra(m-hydroxyphenyl)chlorin for photodynamic therapy in an 'early' squamous cell carcinoma model

S. A. Blant; J. F. Theumann; M. Forrer; G. Wagnieres; H. VandenBergh et al.

Lasers in Medical Science. 1997.

Production of the free radicals O-2(.-) and OH by irradiation of the photosensitizer zinc(II) phthalocyanine

C. Hadjur; G. Wagnières; F. Ihringer; P. Monnier; H. van den Bergh

Journal of Photochemistry and Photobiology B-Biology. 1997.

DOI : 10.1016/S1011-1344(96)07440-4.

Photoinduction of fluorophores in the retina using a 514-nm argon ion laser

J. Inderfurth; G. Wagnieres

German Journal of Ophthalmology. 1997.

Clinical evaluation of a method for detecting superficial transitional cell carcinoma of the bladder by light-induced fluorescence of protoporphyrin IX following topical application of 5-aminolevulinic acid: Preliminary results

P. Jichlinski; M. Forrer; J. Mizeret; T. Glanzmann; D. Braichotte et al.

Lasers in Surgery and Medicine. 1997.

DOI : 10.1002/(SICI)1096-9101(1997)20:4<402::AID-LSM5>3.0.CO;2-U.

Clinical value of fluorescence cystoscopy in the detection of superficial transitional cell carcinomas of the bladder

P. Jichlinski; G. Wagnières; M. Forrer; J. Mizeret; L. Guillou et al.

Annales d'Urologie. 1997.

Endoscopic tissue characterization by frequency-domain fluorescence lifetime imaging (FD-FLIM)

J. Mizeret; G. Wagnières; T. Stepinac; H. VandenBergh

Lasers in Medical Science. 1997.

An optical phantom with tissue-like properties in the visible for use in PDT and fluorescence spectroscopy

G. Wagnières; S. Cheng; M. Zellweger; N. Utke; D. Braichotte et al.

Physics in Medicine and Biology. 1997.

DOI : 10.1088/0031-9155/42/7/014.

Frequency-domain fluorescence lifetime imaging for endoscopic clinical cancer photodetection: Apparatus design and preliminary results

G. Wagnières; J. Mizeret; A. Studzinski; H. Bergh

Journal of Fluorescence. 1997.

DOI : 10.1007/BF02764580.

Clinical imaging fluorescence apparatus for the endoscopic photodetection of early cancers by use of Photofrin II

G. Wagnières; A. Studzinski; D. R. Braichotte; P. Monnier; C. Depeursinge et al.

Applied Optics. 1997.

DOI : 10.1364/AO.36.005608.

Endoscopic fluorescence imaging system for simultaneous visual examination and photodetection of cancers

G. A. Wagnieres; A. P. Studzinski; H. E. vandenBergh

Review of Scientific Instruments. 1997.

DOI : 10.1063/1.1147811.

Clinical assessment of fluorescence cystoscopy during transurethral bladder resection in superficial bladder cancer

P. Jichlinski; G. Wagnieres; M. Forrer; J. Mizeret; L. Guillou et al.

Urological Research. 1997.

DOI : 10.1007/BF00942040.

Light distributors for photodynamic therapy | Les distributeurs de lumiere pour le traitement photodynamique

R. Bays; G. Wagnieres; J. Mizeret; A. Woodtli; M. Forrer et al.

1996. p. 407-409.

Usefulness of fluorescence photodetection of neoplastic urothelial foci in bladder cancer following intravesical instillation of delta-aminolevulinic acid (5-ALA)

P. M. D. Jichlinski; M. Forrer; J. C. Mizeret; D. Braichotte; G. Wagnieres et al.

1996. p. 340-347.

DOI : 10.1117/12.240028.

Design and characterization of a phantom that simultaneously simulates tissue optical properties between 400 and 650 nm

G. Wagnieres; S. Cheng; M. Zellweger; N. Utke; D. Braichotte et al.

1996. p. 94-103.

DOI : 10.1117/12.260824.

Tissue characterization by time-resolved fluorescence spectroscopy of endogenous and exogenous fluorochromes: apparatus design and preliminary results

T. Glanzmann; J.-P. Ballini; P. M. D. Jichlinski; H. Van den Bergh; G. Wagnieres

1996. p. 41-50.

DOI : 10.1117/12.260818.

Measurements by fluorescence microscopy of the time-dependent distribution of meso-tetra-hydroxyphenylchlorin in healthy tissues and chemically induced ''early'' squamous cell carcinoma of the Syrian hamster cheek pouch

S. Andrejevic; J. F. Savary; P. Monnier; C. Fontolliet; D. Braichotte et al.

Journal of Photochemistry and Photobiology B-Biology. 1996.

DOI : 10.1016/S1011-1344(96)07362-9.

Clinical determination of tissue optical properties by endoscopic spatially resolved reflectometry

R. Bays; G. Wagnieres; D. Robert; D. Braichotte; J. F. Savary et al.

Applied Optics. 1996.

In-vivo fluence rate effect in photodynamic therapy of early cancers with tetra(m-hydroxyphenyl)chlorin

S. A. Blant; A. Woodtli; G. Wagnières; C. Fontolliet; H. van den Bergh et al.

Photochemistry and Photobiology. 1996.

DOI : 10.1111/j.1751-1097.1996.tb01862.x.

Optimizing light dosimetry in photodynamic therapy of the bronchi by fluorescence spectroscopy

D. Braichotte; J. F. Savary; T. Glanzmann; P. Monnier; G. Wagnieres et al.

Lasers in Medical Science. 1996.

DOI : 10.1007/BF02134915.

Photodynamic Therapy for Cancer of the Upper Aerodigestive Tract Using Tetra(m-hydroxyphenyl)chlorin

P. Grosjean; J. F. Savary; J. Mizeret; G. Wagnières; A. Woodtli et al.

Journal of Clinical Laser Medicine & Surgery . 1996.

Tetra(m-hydroxyphenyl)chlorin clinical photodynamic therapy of early bronchial and oesophageal cancers

P. Grosjean; J. F. Savary; G. Wagnieres; J. Mizeret; A. Woodtli et al.

Lasers in Medical Science. 1996.

DOI : 10.1007/BF02134913.

Les indications et performances du laser en urologie

F. Schmidlin; P. Jichlinski; G. Delacrétaz; G. Wagnières; H. Leisinger et al.

Médecine et Hygiène. 1996.

Fluorescence excitation and emission spectra of ALA-induced protoporphyrin IX in normal and tumoral tissue of the human bladder

M. Forrer; T. Glanzmann; J. Mizeret; D. Braichotte; G. Wagnieres et al.

1995. p. 84-88.

DOI : 10.1117/12.198705.

Fluorescence imaging photodetection of early cancer in the bronchi with mTHPC and in the bladder with ALA-induced protoporphyrin IX: preliminary clinical results

M. Forrer; J. Mizeret; D. Braichotte; G. Wagnieres; J.-F. Savary et al.

1995. p. 109-114.

DOI : 10.1117/12.203434.

Evaluation with mTHPC of early squamous cell carcinomas of the cheek pouch mucosa of Golden Syrian hamsters as a model for clinical PDT of early cancers in the upper aerodigestive tract, the esophagus

T. Glanzmann; J.-F. Theumann; M. Forrer; D. Braichotte; G. Wagnieres et al.

1995. p. 51-58.

DOI : 10.1117/12.203366.

Clinical measurements of tissue optical properties in the esophagus and in the oral cavity

R. Bays; G. Wagnieres; D. Robert; J. Mizeret; D. Braichotte et al.

1995. p. 388-395.

DOI : 10.1117/12.203382.

Superficial bladder tumors | LES TUMEURS SUPERFICIELLES DE LA VESSIE

P. Jichlinski; J. Mizeret; M. Forrer; H. Van Den Bergh; F. Schmidlin et al.

Revue Medicale de la Suisse Romande. 1995.

Endoscopic frequency-domain fluorescence lifetime imaging for clinical cancer photodetection: apparatus design

G. Wagnieres; J. Mizeret; A. Studzinski; H. Bergh

1995. p. 42-54.

DOI : 10.1117/12.208173.

Importance of fluence rate in photodynamic therapy with ALA-induced PpIX and BPD-MA in a rat bladder tumor model

S. Iinuma; G. Wagnieres; K. T. Schomacker; M. Bamberg; T. Hasan

1995. p. 136-140.

DOI : 10.1117/12.208182.

In-vivo measurement of fluorescence bleaching of meso-tetra hydroxy phenyl chlorin (mTHPC) in the esophagus and the oral cavity

M. Forrer; T. Glanzmann; D. Braichotte; G. Wagnieres; H. Bergh et al.

1995. p. 33-39.

DOI : 10.1117/12.228901.

Endoscopic tissue fluorescence life-time imaging by frequency domain light-induced fluorescence

J. Mizeret; G. Wagnieres; A. Studzinski; C. Shangguan; H. Bergh

1995. p. 40-48.

DOI : 10.1117/12.228902.

In-vivo measurement of fluorescence bleaching of meso-tetra hydroxy phenyl chlorin (mTHPC) in the esophagus and the oral cavity

M. Forrer; T. Glanzmann; D. Braichotte; G. Wagnieres; H. van den Bergh et al.

SPIE Proceedings. 1995.

DOI : 10.1117/12.228901.

Clinical pharmacokinetic studies of photofrin by fluorescence spectroscopy in the oral cavity, the esophagus, and the bronchi

D. R. Braichotte; G. A. Wagnières; R. Bays; P. Monnier; V. Bergh et al.

Cancer. 1995.

DOI : 10.1002/1097-0142(19950601)75:11<2768::AID-CNCR2820751122>3.0.CO;2-I.

Clinical pharmacokinetic studies of tetra(meta-hydroxyphenyl)chlorin in squamous cell carcinoma by fluorescence spectroscopy at 2 wavelengths

D. Braichotte; J.-F. Savary; T. Glanzmann; P. Westermann; S. Folli et al.

International Journal of Cancer. 1995.

DOI : 10.1002/ijc.2910630209.

Pharmacokinetics of meso-(tetrahydroxyphenyl)chlorin (mTHPC) studied by fluorescence spectroscopy on early cancer of the cheek pouch mucosa of Golden Syrian hamsters

T. Glanzmann; J.-F. Theumann; D. Braichotte; M. Forrer; G. Wagnieres et al.

SPIE Proceedings, Optical Biopsy and Fluorescence Spectroscopy and Imaging. 1995.

DOI : 10.1117/12.198706.

Antibody-indocyanin conjugates for immunophotodetection of human squamous cell carcinoma in nude mice

S. Folli; P. Westermann; D. Braichotte; A. Pelegrin; G. Wagnieres et al.

Cancer Research. 1994.

A clinical comparison of the pharmacokinetics of m-THPC and photofrin II as observed by light induced fluorescence

D. Braichotte; J.-F. Savary; G. Wagnières; A. Mudry; C. Fontolliet et al.

SPIE Proceedings. 1994.

DOI : 10.1117/12.166811.

Clinical LIF pharmacokinetic measurements with Photofrin II for optimizing the photodetection of early cancer

D. Braichotte; G. Wagnieres; J. M. Philippoz; R. Bays; H.-B. Ris et al.

1992. p. 229-240.

DOI : 10.1117/12.60952.

Preliminary clinical results on a second generation photosensitizer: mTHPC

D. Braichotte; G. Wagnières; J. M. D. Philippoz; R. Bays; H. B. Ris et al.

1992. International Conference on Photodynamic Therapy and Medical Laser Applications , Milan, Italy , 24-27 June 1992. p. 461-465.

Photoimmunodiagnosis with antibody-fluorescein conjugates: In vitro and in vivo preclinical studies

A. Pelegrin; S. Folli; G. Wagnieres; D. Braichotte; F. Buchegger et al.

Journal of cellular pharmacology. 1992.

Further appraisal of PDI and PDT of early squamous cell carcinomas of the pharynx, oesophagus and bronchi

P. Monnier; C. Fontolliet; G. Wagnières; D. Braichotte; H. van den Berg

1992. International Conference on Photodynamic Therapy and Medical Laser Applications , Milan, Italy , 24-27 June 1992.

Clinical pharmacokinetic studies of Photofrin II by fluorescence spectroscopy

D. Braichotte; G. Wagnières; P. Monnier; R. Bays; H. van den Bergh

Elsevier Science Publishers B.V., 1992.

Immunophotodiagnosis of Colon Carcinomas in Patients Injected with Fluoresceinated Chimeric Antibodies against Carcinoembryonic Antigen

S. Folli; G. Wagnières; A. Pelegrin; J. M. Calmes; D. Braichotte et al.

Proceedings of the National Academy of Sciences of the United States of America. 1992.

DOI : 10.1073/pnas.89.17.7973.

Photochimiothérapie et photodétection du cancer à l'aide de photosensibilisateurs ou de colorants fluorescents

G. Wagnières / A. Châtelain (Dir.)

Lausanne, EPFL, 1992.

DOI : 10.5075/epfl-thesis-1024.

Photofrin II pharmacokinetics and optical dosing in tissue: apparatus and clinical measurements for the pharynx, esophagus, and tracheobronchial tree

D. Braichotte; R. Bays; G. Wagnieres; A. Chatelain; C. W. Burckhardt et al.

Photodynamic Therapy : Basic Principles and Clinical Applications. 1991.

Antibody-fluorescein conjugates for photoimmunodiagnosis of human colon carcinoma in nude mice

A. Pelegrin; S. Folli; F. Buchegger; J. P. Mach; G. Wagnières et al.

Cancer. 1991.

DOI : 10.1002/1097-0142(19910515)67:10<2529::AID-CNCR2820671024>3.0.CO;2-B.

Photodetection of early cancer by laser induced fluorescence of a tumor-selective dye: apparatus design and realization

G. Wagnieres; C. Depeursinge; P. Monnier; M. Savary; P. Cornaz et al.

Proc. SPIE 1203, Photodynamic Therapy: Mechanisms II. 1990.

DOI : 10.1117/12.17649.

Photodetection and photodynamic therapy of "early" squamous cell carcinomas of the pharynx, oesophagus and tracheo-bronchial tree

P. Monnier; M. Savary; C. Fontolliet; G. Wagnières; A. Châtelain et al.

Lasers in Medical Science. 1990.

DOI : 10.1007/BF02031377.