Lijing Xin
Nationalité: P.R. China
EPFL CIBM-MRI
CH F1 532 (Bâtiment CH)
Station 6
1015 Lausanne
+41 21 693 05 97
Office: CH F1 532
EPFL › VPA › VPA-AVP-CP › CIBM › CIBM-MRI
Site web: https://www.cibm.ch/
EPFL CIBM-MRI
CH F1 532 (Bâtiment CH)
Station 6
1015 Lausanne
EPFL CIBM-MRI
CH F1 532 (Bâtiment CH)
Station 6
1015 Lausanne
+41 21 693 05 97
EPFL › SB › IPHYS › IPHYS-GE
Expertise
Spin physics
brain energy metabolism
Schizophrenia
Mood disorders
MRI instrumentation
Creatine kinase imaging (CKI) for in vivo whole-brain mapping of creatine kinase reaction kinetics
Proceedings of the National Academy of Sciences. 2025. DOI : 10.1073/pnas.2505323122.Neurometabolic predictors of mental effort in the frontal cortex
Translational Psychiatry. 2025. DOI : 10.1038/s41398-025-03554-6.Neurochemical characteristics of pathological tissues in epilepsy: A preliminary <sup>1</sup>H MR spectroscopy study at 7 T
European Journal of Radiology Open. 2025. DOI : 10.1016/j.ejro.2025.100640.Rosette Spectroscopic Imaging for Whole-Brain Slab Metabolite Mapping at 7T: Acceleration Potential and Reproducibility
Human Brain Mapping. 2025. DOI : 10.1002/hbm.70176.Fast 3D <sup>31</sup>P B1+ mapping with a weighted stack of spiral trajectory at 7 T
Magnetic resonance in medicine. 2025. DOI : 10.1002/mrm.30321.CEST imaging combined with <SUP>1</SUP>H-MRS reveal the neuroprotective effects of riluzole by improving neurotransmitter imbalances in Alzheimer's disease mice
ALZHEIMERS RESEARCH & THERAPY. 2025. DOI : 10.1186/s13195-025-01672-3.A graphical pipeline platform for MRS data processing and analysis: MRSpecLAB
Frontiers in neuroimaging. 2025. DOI : 10.3389/fnimg.2025.1610658.Rebalance the Inhibitory System in the Elderly Brain: Influence of Balance Learning on GABAergic Inhibition and Functional Connectivity
Human Brain Mapping. 2024. DOI : 10.1002/hbm.70057.Five percent CO<inf>2</inf> inhalation alleviates hippocampal glutamate and water homeostasis disturbance, neuronal damage, and learning-memory impairment in sleep-deprived rats
Neuroprotection. 2024. DOI : 10.1002/nep3.53.A neurometabolic mechanism involving dmPFC/dACC lactate in physical effort-based decision-making
Molecular Psychiatry. 2024. DOI : 10.1038/s41380-024-02726-y.Neurocognition and NMDAR co-agonists pathways in individuals with treatment resistant first-episode psychosis: a 3-year follow-up longitudinal study
Molecular Psychiatry. 2024. DOI : 10.1038/s41380-024-02631-4.NMR and MS reveal characteristic metabolome atlas and optimize esophageal squamous cell carcinoma early detection
Nature Communications. 2024. DOI : 10.1038/s41467-024-46837-0.Twisted pair transmission line coil - a flexible, self-decoupled and robust element for 7 T MRI
Magnetic Resonance Imaging. 2024. DOI : 10.1016/j.mri.2024.02.007.MRI characterization of in vitro clots at 3T and 7T: A technical note
Journal Of Neuroradiology. 2024. DOI : 10.1016/j.neurad.2023.06.003.NMR-based metabolomics combined with metabolic pathway analysis reveals metabolic heterogeneity of colorectal cancer tissue at different anatomical locations and stages
International Journal of Cancer. 2024. DOI : 10.1002/ijc.35273.Effect of circadian rhythm on NAD and other metabolites in human brain
Frontiers In Physiology. 2023. DOI : 10.3389/fphys.2023.1285776.Improved reproducibility of γ-aminobutyric acid measurement from short-echo-time proton MR spectroscopy by linewidth-matched basis sets in LCModel
Nmr In Biomedicine. 2023. DOI : 10.1002/nbm.5056.Developmental changes in cerebral NAD and neuroenergetics of an antioxidant compromised mouse model of schizophrenia
Translational Psychiatry. 2023. DOI : 10.1038/s41398-023-02568-2.Fast in vivo assay of creatine kinase activity in the human brain by P-31 magnetic resonance fingerprinting
Nmr In Biomedicine. 2023. DOI : 10.1002/nbm.4998.High field brain proton magnetic resonance spectroscopy and volumetry in children with chronic, compensated liver disease-A pilot study
Analytical Biochemistry. 2023. DOI : 10.1016/j.ab.2023.115212.Dipolectric antenna for high-field MRI
Magnetic Resonance in Medicine. 2023. DOI : 10.1002/mrm.29719.Redox and Immune Signaling in Schizophrenia: New Therapeutic Potential
International Journal Of Neuropsychopharmacology. 2023. DOI : 10.1093/ijnp/pyad012.Variability and magnitude of brain glutamate levels in schizophrenia: a meta and mega-analysis
Molecular Psychiatry. 2023. DOI : 10.1038/s41380-023-01991-7.Apparent diffusion coefficients of 31P metabolites in the human calf muscle at 7 T
Magnetic Resonance Materials In Physics Biology And Medicine. 2023. DOI : 10.1007/s10334-023-01065-3.Bridging structural MRI with cognitive function for individual level classification of early psychosis via deep learning
Frontiers In Psychiatry. 2023. DOI : 10.3389/fpsyt.2022.1075564.In vivo magnetic resonance P-31-Spectral Analysis With Neural Networks: 31P-SPAWNN
Magnetic Resonance in Medicine. 2022. DOI : 10.1002/mrm.29446.gamma-aminobutyric acid measurement in the human brain at 7 T: Short echo-time or Mescher-Garwood editing
Nmr In Biomedicine. 2022. DOI : 10.1002/nbm.4706.Glutathione in the nucleus accumbens regulates motivation to exert reward-incentivized effort
eLife. 2022. DOI : 10.7554/eLife.77791.Timely N-Acetyl-Cysteine and Environmental Enrichment Rescue Oxidative Stress-Induced Parvalbumin Interneuron Impairments via MMP9/RAGE Pathway: A Translational Approach for Early Intervention in Psychosis
Schizophrenia Bulletin. 2021. DOI : 10.1093/schbul/sbab066.Metabolic and transcriptomic profiles of glioblastoma invasion revealed by comparisons between patients and corresponding orthotopic xenografts in mice
Acta Neuropathologica Communications. 2021. DOI : 10.1186/s40478-021-01232-4.In vivo macromolecule signals in rat brain 1 H‐MR spectra at 9.4T: Parametrization, spline baseline estimation, and T 2 relaxation times
Magnetic Resonance in Medicine. 2021. DOI : 10.1002/mrm.28910.Brain NAD Is Associated With ATP Energy Production and Membrane Phospholipid Turnover in Humans
Frontiers In Aging Neuroscience. 2020. DOI : 10.3389/fnagi.2020.609517.Contribution of macromolecules to brain H-1 MR spectra: Experts' consensus recommendations
Nmr In Biomedicine. 2020. DOI : 10.1002/nbm.4393.In vivo P-31 magnetic resonance spectroscopy study of mouse cerebral NAD content and redox state during neurodevelopment
Scientific Reports. 2020. DOI : 10.1038/s41598-020-72492-8.Magnetic resonance spectroscopy in the rodent brain: Experts' consensus recommendations
Nmr In Biomedicine. 2020. DOI : 10.1002/nbm.4325.Advanced single voxel 1 H magnetic resonance spectroscopy techniques in humans: Experts' consensus recommendations
NMR in Biomedicine. 2020. DOI : 10.1002/nbm.4236.MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in schizophrenia patients
Molecular Psychiatry. 2020. DOI : 10.1038/s41380-019-0393-5.Lactate measurement by neurochemical profiling in the dorsolateral prefrontal cortex at 7T: accuracy, precision, and relaxation times
Magnetic Resonance in Medicine. 2020. DOI : 10.1002/mrm.28066.Glutamine-to-glutamate ratio in the nucleus accumbens predicts effort-based motivated performance in humans
Neuropsychopharmacology. 2020. DOI : 10.1038/s41386-020-0760-6.N-Acetyl-Cysteine Supplementation Improves Functional Connectivity Within the Cingulate Cortex in Early Psychosis: A Pilot Study
International Journal of Neuropsychopharmacology. 2019. DOI : 10.1093/ijnp/pyz022.Association between Brain and Plasma Glutamine Levels in Healthy Young Subjects Investigated by MRS and LC/MS
Nutrients. 2019. DOI : 10.3390/nu11071649.Nucleus accumbens neurochemistry in human anxiety: A 7 T 1H-MRS study
Eur Neuropsychopharmacol. 2019. DOI : 10.1016/j.euroneuro.2018.12.015.Improved off‐resonance phase behavior using a phase‐inverted adiabatic half‐passage pulse for 13 C MRS in humans at 7 T
NMR in Biomedicine. 2019. DOI : 10.1002/nbm.4171.Metabolite concentration changes associated with positive and negative BOLD responses in the human visual cortex: A functional MRS study at 7 Tesla
Journal of Cerebral Blood Flow & Metabolism. 2019. DOI : 10.1177/0271678X19831022.Magnetic Resonance Spectroscopy in Schizophrenia: Evidence for Glutamatergic Dysfunction and Impaired Energy Metabolism
Neurochemical research. 2019. DOI : 10.1007/s11064-018-2521-z.MP2RAGE and Susceptibility-Weighted Imaging in Lesional Epilepsy at 7T
Journal of Neuroimaging. 2018. DOI : 10.1111/jon.12523.Cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex
Psychopharmacology. 2018. DOI : 10.1007/s00213-017-4745-z.Clinical Neuroimaging Using 7 T MRI: Challenges and Prospects
Journal of neuroimaging : official journal of the American Society of Neuroimaging. 2018. DOI : 10.1111/jon.12481.Nutritional Ketosis Increases NAD+/NADH Ratio in Healthy Human Brain: An in Vivo Study by 31P-MRS
Frontiers in Nutrition. 2018. DOI : 10.3389/fnut.2018.00062.N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial
Translational Psychiatry. 2018. DOI : 10.1038/s41398-018-0266-8.A practical guide to in vivo proton magnetic resonance spectroscopy at high magnetic fields
Analytical biochemistry. 2017. DOI : 10.1016/j.ab.2016.10.019.Genetic Polymorphism Associated Prefrontal Glutathione and Its Coupling With Brain Glutamate and Peripheral Redox Status in Early Psychosis
Schizophrenia bulletin. 2016. DOI : 10.1093/schbul/sbw038.Assessment of metabolic fluxes in the mouse brain in vivo using (1)H-[(13)C] NMR spectroscopy at 14.1 Tesla
Journal of Cerebral Blood Flow & Metabolism. 2015. DOI : 10.1038/jcbfm.2014.251.Glutathione deficit impairs myelin maturation: relevance for white matter integrity in schizophrenia patients
Molecular Psychiatry. 2015. DOI : 10.1038/mp.2014.88.A double-quadrature radiofrequency coil design for proton-decoupled carbon-13 magnetic resonance spectroscopy in humans at 7T
Magnetic Resonance in Medicine. 2015. DOI : 10.1002/mrm.25171.In vivo quantification of neuro-glial metabolism and glial glutamate concentration using 1H-[13C] MRS at 14.1T
Journal of Neurochemistry (JNC). 2014. DOI : 10.1111/jnc.12479.Non-invasive diagnostic biomarkers for estimating the onset time of permanent cerebral ischemia
Journal of Cerebral Blood Flow & Metabolism. 2014. DOI : 10.1038/jcbfm.2014.155.Are glutamate and lactate increases ubiquitous to physiological activation? A 1H functional MR spectroscopy study during motor activation in human brain at 7Tesla
NeuroImage. 2014. DOI : 10.1016/j.neuroimage.2014.02.016.Is the macromolecule signal tissue-specific in healthy human brain? A 1H MRS study at 7 tesla in the occipital lobe
Magnetic Resonance in Medicine. 2014. DOI : 10.1002/mrm.24995.Net increase of lactate and glutamate concentration in activated human visual cortex detected with magnetic resonance spectroscopy at 7 tesla
Journal of neuroscience research. 2013. DOI : 10.1002/jnr.23194.Quantification of the neurochemical profile using simulated macromolecule resonances at 3 T
NMR in biomedicine. 2013. DOI : 10.1002/nbm.2896.Single spin-echo T 2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain
Magma (New York, N.Y.). 2013. DOI : 10.1007/s10334-013-0378-3.Characterization of sustained BOLD activation in the rat barrel cortex and Neurochemical consequences
Neuroimage. 2013. DOI : 10.1016/j.neuroimage.2013.02.042.Proton T(1) relaxation times of metabolites in human occipital white and gray matter at 7 T
Magnetic Resonance in Medicine. 2013. DOI : 10.1002/mrm.24352.Investigating the metabolic changes due to visual stimulation using functional proton magnetic resonance spectroscopy at 7 T
Journal of Cerebral Blood Flow & Metabolism. 2012. DOI : 10.1038/jcbfm.2012.33.H-1-[C-13] NMR Spectroscopy of the Rat Brain During Infusion of [2-C-13] Acetate at 14.1 T
Magnetic Resonance in Medicine. 2010. DOI : 10.1002/mrm.22359.Direct in vivo measurement of glycine and the neurochemical profile in the rat medulla oblongata
Nmr In Biomedicine. 2010. DOI : 10.1002/nbm.1537.Quantification of brain glycogen concentration and turnover through localized C-13 NMR of both the C1 and C6 resonances
Nmr In Biomedicine. 2010. DOI : 10.1002/nbm.1460.In vivo measurement of glycine with short echo-time H-1 MRS in human brain at 7 T
Magnetic Resonance Materials In Physics Biology And Medicine. 2009. DOI : 10.1007/s10334-008-0152-0.Comparison of T-1 Relaxation Times of the Neurochemical Profile in Rat Brain at 9.4 Tesla and 14.1 Tesla
Magnetic Resonance in Medicine. 2009. DOI : 10.1002/mrm.22022.Selective Resonance Suppression H-1-[C-13] NMR Spectroscopy With Asymmetric Adiabatic RF Pulses
Magnetic Resonance in Medicine. 2009. DOI : 10.1002/mrm.21829.Quantification of in vivo short echo-time proton magnetic resonance spectra at 14.1 T using two different approaches of modelling the macromolecule spectrum
Measurement Science and Technology. 2009. DOI : 10.1088/0957-0233/20/10/104034.Proton T-2 relaxation time of J-coupled cerebral metabolites in rat brain at 9.4T
Nmr In Biomedicine. 2008. DOI : 10.1002/nbm.1205.In vivo H-1 NMR measurement of glycine in rat brain at 9.4 T at short echo time
Magnetic Resonance in Medicine. 2008. DOI : 10.1002/mrm.21695.Non-invasive quantification of brain glycogen absolute concentration
Journal of Neurochemistry (JNC). 2008. DOI : 10.1111/j.1471-4159.2008.05717.x.H-1 NMR spectroscopy of rat brain in vivo at 14.1 Tesla: Improvements in quantification of the neurochemical profile
Journal of Magnetic Resonance. 2008. DOI : 10.1016/j.jmr.2008.06.019.Enseignement et PhD
Doctorant·es actuel·les
Zhiwei Huang, Rafael Ignacio De la Sotta Vargas, Ying Xiao, Yang Gao
A co-dirigé les thèses EPFL de
Songi Lim, Mark Stephan Widmaier, Xinyu Liu