Matthias Lütolf
EPFL SV IBI-SV UPLUT
AI 1208 (Bâtiment AI)
Station 15
CH-1015 Lausanne
EPFL SB ISIC-GE
AI 1208 (Bâtiment AI)
Station 19
CH-1015 Lausanne
Mission
Research in the Lutolf lab is at the interface of stem cell biology and bioengineering to gain fundamental insight into how complex three-dimensional (3D) microenvironments, termed niches, control the behavior of stem cells. We exploit this know-how to develop novel technologies for maintaining stem cells in vitro and for controlling their differentiation and self-organization into 3D functional tissues (organoids).
Biography
Professor Matthias Lutolf is Head of the Laboratory of Stem Cell Bioengineering. He was trained as a Materials Engineer at ETH Zurich where he also carried out his Ph.D. studies on the development of a novel class of biomaterials for tissue engineering (awarded with ETH medal). Lutolf carried out postdoctoral studies at the Baxter Laboratory in Stem Cell Biology at Stanford University. He started up his independent research group at EPFL in 2007 with a European Young Investigator (EURYI) award. By interfacing advanced biomaterials engineering, microtechnology and stem cell biology, a major goal in his lab is to uncover mechanisms of stem cell fate regulation; knowledge that will contribute to better ways to grow stem cells in culture and use them for various new applications.
Publications
http://scholar.google.ch/citations?user=8cetpGIAAAAJ
Fields of expertise
Bioengineering, Stem Cells, Biomaterials, Tissue Engineering, Microfluidics, Single Cell Analysis, High-Throughput Screening
Teaching & PhD
Teaching
- Life Sciences Engineering,
PhD Programs
- Doctoral Program in Biotechnology and Bioengineering
- Doctoral Program in Chemistry and Chemical Engineering
PhD Students
Giger Sonja
Girgin Mehmet Ugur
Hofer Moritz
Hübscher Tania
Mashinchian Omid
Mitrofanova Olga
Nikolaev Mikhail
Park Jisoo
Rezakhani Saba
Rivest François Réal
Vallmajó Martín Queralt
Vianello Stefano Davide
Past PhD Students
Allazetta Simone ...Brandenberg Nathalie ...
Brünggel Kym Lorenz ...
Cosson Steffen ...
Devaud Yannick Robert ...
Girotra Mukul ...
Höhnel Sylke ...
Kobel Stefan ...
Kolb Laura ...
Lienemann Philipp Sebastian ...
Mosiewicz Katarzyna ...
Negro Andrea ...
Nikitin Gennady ...
Okawa Yuya ...
Ranga Adrian ...
Roch Aline ...
Tabata Yoji ...
Trachsel Vincent ...
Courses
Biomaterials
This course covers the fundamental concepts behind the design, function and application of state-of-the-art biomaterials, that is, materials that are designed based on a molecular understanding of their interactions with biological systems.
Stem cell biology and technology
This course introduces the fundamentals of stem cell biology, with a particular focus on the role of stem cells during development, tissue homeostasis/regeneration and disease.
Tissue engineering
Tissue engineering is an interdisciplinary field that broadly impacts human health. This course provides students an overview of how engineering approaches can be used to investigate and manipulate cell and tissue functions and enable students to be on th...