Epithelial Wnt secretion drives the progression of inflammation-induced colon carcinoma in murine model
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Iscience. 2021. DOI : 10.1016/j.isci.2021.103369.TBX3 acts as tissue-specific component of the Wnt/beta-catenin enhanceosome
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Elife. 2020. DOI : 10.7554/eLife.58123.Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/beta-catenin signaling
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Genes & Development. 2018. DOI : 10.1101/gad.315531.118.The Multi-kinase Inhibitor Debio 0617B Reduces Maintenance and Self-renewal of Primary Human AML CD34(+) Stem/Progenitor Cells
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Molecular Cancer Therapeutics. 2017. DOI : 10.1158/1535-7163.Mct-16-0889.The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma
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Scientific Reports. 2016. DOI : 10.1038/srep22113.Wnt Ligands Secreted by Subepithelial Mesenchymal Cells Are Essential for the Survival of Intestinal Stem Cells and Gut Homeostasis
T. Valenta; B. Degirmenci; A. E. Moor; P. Herr; D. Zimmerli
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Cell Reports. 2016. DOI : 10.1016/j.celrep.2016.03.088.Debio 0617B Inhibits Growth of STAT3-Driven Solid Tumors through Combined Inhibition of JAK, SRC, and Class III/V Receptor Tyrosine Kinases
M. Murone; A. V. Chessex; A. Attinger; R. Ramachandra; S. J. Shetty
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Molecular Cancer Therapeutics. 2016. DOI : 10.1158/1535-7163.Mct-15-0974.CL9/9L-beta-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer
A. E. Moor; P. Anderle; C. Cantu; P. Rodriguez; N. Wiedemann
et al.
Ebiomedicine. 2015. DOI : 10.1016/j.ebiom.2015.10.030.The Bcl9-beta-catenin interface as a potential therapeutic target for colorectal cancer
A. E. Moor / M. Aguet (Dir.)
Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6449. Pax6-dependent, but beta-catenin-independent, function of Bcl9 proteins in mouse lens development
C. Cantù; D. Zimmerli; G. Hausmann; T. Valenta; A. Moor
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Genes & Development. 2014. DOI : 10.1101/gad.246140.114.The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription
C. Cantu; T. Valenta; G. Hausmann; N. Vilain; M. Aguet
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Development. 2013. DOI : 10.1242/dev.093591.Defining new criteria for selection of cell-based intestinal models using publicly available databases
J. Christensen; S. El-Gebali; M. Natoli; T. Sengstag; M. Delorenzi
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Bmc Genomics. 2012. DOI : 10.1186/1471-2164-13-274.Role of Bcl9 and Bcl9l in Homeostasis, Regeneration and Tumorigenesis of the Gastrointestinal Epithelium
N. Wiedemann / M. Aguet (Dir.)
Lausanne, EPFL, 2011. DOI : 10.5075/epfl-thesis-5207. The Creation of EBV Biotech
N. Mackinnon
2011Gene expression analysis of metastases and IL-1R1 characterization in a NALP3 mouse model
H. Fournier
2011Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas
J. Deka; N. Wiedemann; P. Anderle Pedone; F. Murphy-Seiler; J. Bultinck
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Cancer Research. 2010. DOI : 10.1158/0008-5472.CAN-10-0148.BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration
A. S. Brack; F. Murphy-Seiler; J. Hanifi; J. Deka; S. Eyckerman
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Developmental biology. 2009. DOI : 10.1016/j.ydbio.2009.08.014.A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer
P. Farmer; H. Bonnefoi; P. Anderle; D. Cameron; P. Wirapati
et al.
Nature medicine. 2009. DOI : 10.1038/nm.1908.SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development
R. L. van Bezooijen; M. C. Deruiter; N. Vilain; R. M. Monteiro; A. Visser
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Developmental dynamics : an official publication of the American Association of Anatomists. 2007. DOI : 10.1002/dvdy.21054.Normal hemopoiesis and lymphopoiesis in the combined absence of numb and numblike
A. Wilson; D. L. Ardiet; C. Saner; N. Vilain; F. Beermann
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The Journal of Immunology. 2007. DOI : 10.4049/jimmunol.178.11.6746.Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation
X. D. Wang; C. C. Leow; J. Zha; Z. Tang; Z. Modrusan
et al.
Developmental Biology. 2006. DOI : 10.1016/j.ydbio.2005.11.009.Notch1 is required for neuronal and glial differentiation in the cerebellum
S. Lutolf; F. Radtke; M. Aguet; U. Suter; V. Taylor
Development. 2002. Notch1 control of oligodendrocyte differentiation in the spinal cord
S. Genoud; C. Lappe-Siefke; S. Goebbels; F. Radtke; M. Aguet
et al.
Journal of Cell Biology (JCB). 2002. DOI : 10.1083/jcb.200202002.Multiple roles of mouse Numb in tuning developmental cell fates
O. Zilian; C. Saner; L. Hagedorn; H. Y. Lee; E. Sauberli
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Current Biology. 2001. DOI : 10.1016/S0960-9822(01)00149-X.Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
A. Rangarajan; C. Talora; R. Okuyama; M. Nicolas; C. Mammucari
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EMBO Journal. 2001. DOI : 10.1093/emboj/20.13.3427.The Genetics Company, Inc. - A newly founded Swiss Biotech Company
M. Jenni; K. Basler; E. Hafen; M. Aguet
CHIMIA. 2000. Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells
F. Radtke; I. Ferrero; A. Wilson; R. Lees; M. Aguet
et al.
Journal of Experimental Medicine. 2000. DOI : 10.1084/jem.191.7.1085.VEGF is required for growth and survival in neonatal mice
H. P. Gerber; K. J. Hillan; A. M. Ryan; J. Kowalski; G. A. Keller
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Development. 1999. The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor
S. D. Spencer; F. Di Marco; J. Hooley; S. Pitts-Meek; M. Bauer
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Journal of Experimental Medicine. 1998. DOI : 10.1084/jem.187.4.571.Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice
D. H. Kaplan; V. Shankaran; A. S. Dighe; E. Stockert; M. Aguet
et al.
Proceedings Of The National Academy Of Sciences Of The United States Of America (PNAS). 1998. DOI : 10.1073/pnas.95.13.7556.The role of antibody concentration and avidity in antiviral protection
M. F. Bachmann; U. Kalinke; A. Althage; G. Freer; C. Burkhart
et al.
Science. 1997. DOI : 10.1126/science.276.5321.2024.Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes
B. Wang; I. Andre; A. Gonzalez; J. D. Katz; M. Aguet
et al.
Proceedings Of The National Academy Of Sciences Of The United States Of America (PNAS). 1997. DOI : 10.1073/pnas.94.25.13844.The gene for the ligand binding chain of the human interferon gamma receptor
G. Merlin; B. J. van der Leede; K. McKune; N. Knezevic; W. Bannwarth
et al.
Immunogenetics. 1997. DOI : 10.1007/s002510050223.The IFN gamma receptor: A paradigm for cytokine receptor signaling
E. A. Bach; M. Aguet; R. D. Schreiber
Annual Review of Immunology. 1997. DOI : 10.1146/annurev.immunol.15.1.563.A negative regulatory region in the intracellular domain of the human interferon-alpha receptor
V. C. Gibbs; M. Takahashi; M. Aguet; A. Chuntharapai
Journal of Biological Chemistry. 1996. DOI : 10.1074/jbc.271.45.28710.Ligand-induced assembly and activation of the gamma interferon receptor in intact cells
E. A. Bach; J. W. Tanner; S. Marsters; A. Ashkenazi; M. Aguet
et al.
Molecular and Cellular Biology. 1996. DOI : 10.1128/MCB.16.6.3214.Mice lacking the IFN-gamma receptor have impaired ability to resolve a lung eosinophilic inflammatory response associated with a prolonged capacity of T cells to exhibit a Th2 cytokine profile
A. J. Coyle; S. Tsuyuki; C. Bertrand; S. Huang; M. Aguet
et al.
The Journal of Immunology. 1996. Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-alpha double-deficient mice
H. P. Eugster; M. Muller; U. Karrer; B. D. Car; B. Schnyder
et al.
Int Immunol. 1996. DOI : 10.1093/intimm/8.1.23.Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
M. A. Meraz; J. M. White; K. C. Sheehan; E. A. Bach; S. J. Rodig
et al.
Cell. 1996. DOI : 10.1016/S0092-8674(00)81288-X.Generation of nitric oxide and clearance of interferon-gamma after BCG infection are impaired in mice that lack the interferon-gamma receptor
R. Kamijo; J. Gerecitano; D. Shapiro; S. J. Green; M. Aguet
et al.
Journal of Inflammation. 1995. The in vivo antiviral activity of interleukin-12 is mediated by gamma interferon
L. Ozmen; M. Aguet; G. Trinchieri; G. Garotta
Journal of Virology. 1995. DOI : 10.1128/jvi.69.12.8147-8150.1995.Antiviral Protection by Vesicular Stomatitis Virus-Specific Antibodies in Alpha/Beta Interferon Receptor-Deficient Mice
U. Steinhoff; U. Muller; A. Schertler; H. Hengartner; M. Aguet
et al.
Journal of Virology. 1995. DOI : 10.1128/jvi.69.4.2153-2158.1995.Ligand-induced autoregulation of IFN-gamma receptor beta chain expression in T helper cell subsets
E. A. Bach; S. J. Szabo; A. S. Dighe; A. Ashkenazi; M. Aguet
et al.
Science. 1995. DOI : 10.1126/science.270.5239.1215.Variable region cDNA sequences and characterization of murine anti-human interferon gamma receptor monoclonal antibodies that inhibit receptor binding by interferon gamma
A. Bridges; A. Birch; G. Williams; M. Aguet; D. Schlatter
et al.
Molecular Immunology. 1995. DOI : 10.1016/0161-5890(95)00114-X.Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA
O. Cases; I. Seif; J. Grimsby; P. Gaspar; K. Chen
et al.
Science. 1995. DOI : 10.1126/science.7792602.Immune defence in mice lacking type I and/or type II interferon receptors
M. F. van den Broek; U. Muller; S. Huang; R. M. Zinkernagel; M. Aguet
Immunol Rev. 1995. DOI : 10.1111/j.1600-065X.1995.tb00090.x.Expansion of gamma delta+ T cells in BALB/c mice infected with Leishmania major is dependent upon Th2-type CD4+ T cells
J. P. Rosat; F. Conceicao-Silva; G. A. Waanders; F. Beermann; A. Wilson
et al.
Infection and Immunity. 1995. Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response
K. Swihart; U. Fruth; N. Messmer; K. Hug; R. Behin
et al.
Journal of Experimental Medicine. 1995. DOI : 10.1084/jem.181.3.961.Cd40 Ligand Has Potent Antiviral Activity
J. Ruby; H. Bluethmann; M. Aguet; I. A. Ramshaw
Nature Medicine. 1995. DOI : 10.1038/nm0595-437.Role of Interferon-Gamma in Interleukin 12-Induced Pathology in Mice
B. D. Car; V. M. Eng; B. Schnyder; M. Lehir; A. N. Shakhov
et al.
American Journal of Pathology. 1995. Dissection of the extracellular human interferon gamma receptor alpha-chain into two immunoglobulin-like domains. Production in an Escherichia coli thioredoxin gene fusion expression system and recognition by neutralizing antibodies
G. Williams; N. Ruegg; A. Birch; C. Weber; K. Hofstadter
et al.
Biochemistry. 1995. DOI : 10.1021/bi00005a036.Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon gamma and tumor necrosis factor alpha
I. E. Flesch; J. H. Hess; S. Huang; M. Aguet; J. Rothe
et al.
Journal of Experimental Medicine. 1995. DOI : 10.1084/jem.181.5.1615.Inducible gene targeting in mice
R. Kuhn; F. Schwenk; M. Aguet; K. Rajewsky
Science. 1995. DOI : 10.1126/science.7660125.The stimulatory effects of interleukin (IL)-12 on hematopoiesis are antagonized by IL-12-induced interferon gamma in vivo
V. M. Eng; B. D. Car; B. Schnyder; M. Lorenz; S. Lugli
et al.
Journal of Experimental Medicine. 1995. DOI : 10.1084/jem.181.5.1893.IFN-gamma receptor-deficient mice are hypersensitive to the anti-CD3-induced cytokine release syndrome and thymocyte apoptosis. Protective role of endogenous nitric oxide
P. Matthys; G. Froyen; L. Verdot; S. Huang; H. Sobis
et al.
The Journal of Immunology. 1995. Development of Antimalaria Immunity in Mice Lacking Ifn-Gamma Receptor
M. Tsuji; Y. Miyahira; R. S. Nussenzweig; M. Aguet; M. Reichel
et al.
The Journal of Immunology. 1995. Involvement of Ifn-Gamma in Bacillus Calmette-Guerin-Induced but Not in Tumor-Induced Sensitization to Tnf-Induced Lethality
A. Cauwels; P. Brouckaert; J. Grooten; S. Huang; M. Aguet
et al.
The Journal of Immunology. 1995. MHC antigens in interferon gamma (IFN gamma) receptor deficient mice: IFN gamma-dependent up-regulation of MHC class II in renal tubules
C. Haas; B. Ryffel; M. Aguet; M. Le Hir
Kidney Int. 1995. DOI : 10.1038/ki.1995.470.Antiviral activity of autocrine interferon-beta requires the presence of a functional interferon type I receptor
V. Rousseau; I. Cremer; E. Lauret; I. Riviere; M. Aguet
et al.
Journal of Interferon & Cytokine Research. 1995. DOI : 10.1089/jir.1995.15.785.Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase
Y. L. Yang; L. F. Reis; J. Pavlovic; A. Aguzzi; R. Schafer
et al.
EMBO Journal. 1995. DOI : 10.1002/j.1460-2075.1995.tb00300.x.Antiviral Defense in Mice Lacking Both Alpha/Beta and Gamma-Interferon Receptors
M. F. Vandenbroek; U. Muller; S. Huang; M. Aguet; R. M. Zinkernagel
Journal of Virology. 1995. DOI : 10.1128/jvi.69.8.4792-4796.1995.Role of Interferon-Gamma in Contact Hypersensitivity Assessed in Interferon-Gamma Receptor-Deficient Mice
M. Saulnier; S. Huang; M. Aguet; B. Ryffel
Toxicology. 1995. DOI : 10.1016/0300-483X(95)03101-K.Theiler's virus infection of 129Sv mice that lack the interferon alpha/beta or interferon gamma receptors
L. Fiette; C. Aubert; U. Muller; S. Huang; M. Aguet
et al.
Journal of Experimental Medicine. 1995. DOI : 10.1084/jem.181.6.2069.Functional role of type I and type II interferons in antiviral defense
U. Muller; U. Steinhoff; L. F. Reis; S. Hemmi; J. Pavlovic
et al.
Science. 1994. DOI : 10.1126/science.8009221.Interferon gamma receptor deficient mice are resistant to endotoxic shock
B. D. Car; V. M. Eng; B. Schnyder; L. Ozmen; S. Huang
et al.
Journal of Experimental Medicine. 1994. DOI : 10.1084/jem.179.5.1437.The Transcription Factor Mtf-1 Is Essential for Basal and Heavy Metal-Induced Metallothionein-I Gene-Expression
F. Radtke; R. Heuchel; O. Georgiev; G. Stark; M. Aguet
et al.
Journal of Cellular Biochemistry. 1994. Susceptibility to Scrapie in Mice Is Dependent on Prpc
C. Weissmann; H. Bueler; M. Fischer; A. Sauer; M. Aguet
Philosophical Transactions of the Royal Society of London Series B-Biological Sciences. 1994. DOI : 10.1098/rstb.1994.0040.Signaling Steps Involving the Cytoplasmic Domain of the Interferon-Gamma Receptor Alpha-Subunit Are Not Species-Specific
R. Bohni; S. Hemmi; M. Aguet
Journal of Biological Chemistry. 1994. DOI : 10.1016/S0021-9258(17)36657-7.IFN-gamma receptor-deficient mice generate antiviral Th1-characteristic cytokine profiles but altered antibody responses
V. E. Schijns; B. L. Haagmans; E. O. Rijke; S. Huang; M. Aguet
et al.
The Journal of Immunology. 1994. Mice devoid of interferon regulatory factor 1 (IRF-1) show normal expression of type I interferon genes
L. F. Reis; H. Ruffner; G. Stark; M. Aguet; C. Weissmann
EMBO Journal. 1994. DOI : 10.1002/j.1460-2075.1994.tb06805.x.The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression
R. Heuchel; F. Radtke; O. Georgiev; G. Stark; M. Aguet
et al.
EMBO Journal. 1994. DOI : 10.1002/j.1460-2075.1994.tb06581.x.PrP-deficient mice are resistant to scrapie
C. Weissmann; H. Bueler; M. Fischer; A. Sailer; A. Aguzzi
et al.
Annals of the New York Academy of Sciences. 1994. DOI : 10.1111/j.1749-6632.1994.tb38913.x.A novel member of the interferon receptor family complements functionality of the murine interferon gamma receptor in human cells
S. Hemmi; R. Bohni; G. Stark; F. Di Marco; M. Aguet
Cell. 1994. DOI : 10.1016/0092-8674(94)90355-7.Mice that lack the interferon-gamma receptor have profoundly altered responses to infection with Bacillus Calmette-Guerin and subsequent challenge with lipopolysaccharide
R. Kamijo; J. Le; D. Shapiro; E. A. Havell; S. Huang
et al.
Journal of Experimental Medicine. 1993. DOI : 10.1084/jem.178.4.1435.Molecular biology of prion diseases
C. Weissmann; H. Bueler; M. Fischer; H. Bluethmann; M. Aguet
Dev Biol Stand. 1993. Generation of nitric oxide and induction of major histocompatibility complex class II antigen in macrophages from mice lacking the interferon gamma receptor
R. Kamijo; D. Shapiro; J. Le; S. Huang; M. Aguet
et al.
Proceedings Of The National Academy Of Sciences Of The United States Of America (PNAS). 1993. DOI : 10.1073/pnas.90.14.6626.Role of Prp in Prion Diseases
C. Weissmann; H. Bueler; A. Sailer; M. Fischer; M. Aguet
et al.
British Medical Bulletin. 1993. Mice devoid of PrP are resistant to scrapie
H. Bueler; A. Aguzzi; A. Sailer; R. A. Greiner; P. Autenried
et al.
Cell. 1993. DOI : 10.1016/0092-8674(93)90360-3.Immune response in mice that lack the interferon-gamma receptor
S. Huang; W. Hendriks; A. Althage; S. Hemmi; H. Bluethmann
et al.
Science. 1993. DOI : 10.1126/science.8456301.Role of the Prp Gene in Transmissible Spongiform Encephalopathies
C. Weissmann; H. Bueler; M. Fischer; M. Aguet
Intervirology. 1993. DOI : 10.1159/000150307.Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
H. Bueler; M. Fischer; Y. Lang; H. Bluethmann; H. P. Lipp
et al.
Nature. 1992. DOI : 10.1038/356577a0.Functional characterization of a hybrid human-mouse interferon gamma receptor: evidence for species-specific interaction of the extracellular receptor domain with a putative signal transducer
S. Hemmi; G. Merlin; M. Aguet
Proceedings Of The National Academy Of Sciences Of The United States Of America (PNAS). 1992. DOI : 10.1073/pnas.89.7.2737.Molecular cloning of interferon receptors: a short review
M. Aguet
British Journal of Haematology. 1991. DOI : 10.1111/j.1365-2141.1991.tb08109.x.The interferon-gamma receptor: a comparison with other cytokine receptors
M. Aguet
Journal of Interferon Research. 1990. DOI : 10.1089/jir.1990.10.551.Rapid increase of the human IFN-gamma receptor phosphorylation in response to human IFN-gamma and phorbol myristate acetate. Involvement of different serine/threonine kinases
C. Mao; G. Merlin; R. Ballotti; M. Metzler; M. Aguet
The Journal of Immunology. 1990. Differential regulation of the human IFN-gamma receptor expression in Raji and IM9 lymphoblastoid cells versus THP-1 monocytic cells by IFN-gamma and phorbol myristate acetate
C. Mao; G. Merlin; M. Aguet
The Journal of Immunology. 1990. Human chromosome 21 is necessary and sufficient to confer human IFN gamma responsiveness to somatic cell hybrids expressing the cloned human IFN gamma receptor gene
T. Fischer; A. Rehm; M. Aguet; K. Pfizenmaier
Cytokine. 1990. DOI : 10.1016/1043-4666(90)90010-Q.Molecular characterization of the human interferon-gamma receptor: analysis of polymorphism and glycosylation
C. Mao; M. Aguet; G. Merlin
Journal of Interferon Research. 1989. DOI : 10.1089/jir.1989.9.659.Cloning of murine interferon gamma receptor cDNA: expression in human cells mediates high-affinity binding but is not sufficient to confer sensitivity to murine interferon gamma
S. Hemmi; P. Peghini; M. Metzler; G. Merlin; Z. Dembic
et al.
Proceedings Of The National Academy Of Sciences Of The United States Of America (PNAS). 1989. DOI : 10.1073/pnas.86.24.9901.Binding and Internalization of Gold-Labeled Ifn-Gamma by Human Raji Cells
L. Filgueira; P. Groscurth; M. Aguet
The Journal of Immunology. 1989. High affinity human IFN-gamma-binding capacity is encoded by a single receptor gene located in proximity to c-ros on human chromosome region 6q16 to 6q22
K. Pfizenmaier; K. Wiegmann; P. Scheurich; M. Kronke; G. Merlin
et al.
The Journal of Immunology. 1988. Molecular cloning and expression of the human interferon-gamma receptor
M. Aguet; Z. Dembic; G. Merlin
Cell. 1988. DOI : 10.1016/0092-8674(88)90050-5.Functional analysis of T lymphocyte subsets in antiviral host defense
T. P. Leist; S. P. Cobbold; H. Waldmann; M. Aguet; R. M. Zinkernagel
The Journal of Immunology. 1987. Purification of human gamma interferon receptors by sequential affinity chromatography on immobilized monoclonal antireceptor antibodies and human gamma interferon
M. Aguet; G. Merlin
Journal of Experimental Medicine. 1987. DOI : 10.1084/jem.165.4.988.Absence of interferon- receptors on hairy cells from a patient resistant to interferon- therapy
C. Billard; F. Sigaux; D. Ferbus; S. Castaigne; G. Flandrin
et al.
Cancer journal (Villejuif). 1987. Induction, maintenance, and reinduction of tumoricidal activity in bone marrow-derived mononuclear phagocytes by Corynebacterium parvum. Evidence for the involvement of a T cell- and interferon-gamma-independent pathway of macrophage activation
R. Keller; R. Keist; P. H. Van der Meide; P. Groscurth; M. Aguet
et al.
The Journal of Immunology. 1987. Lack of correlation between serum titres of interferon alpha, beta, natural killer cell activity and clinical susceptibility in mice infected with two isolates of lymphocytic choriomeningitis virus
T. P. Leist; M. Aguet; M. Hassig; D. C. Pevear; C. J. Pfau
et al.
Journal of General Virology. 1987. DOI : 10.1099/0022-1317-68-8-2213.A monoclonal antibody against altered LFA-1 induces proliferation and lymphokine release of cloned T cells
H. Pircher; P. Groscurth; S. Baumhutter; M. Aguet; R. M. Zinkernagel
et al.
European Journal of Immunology. 1986. DOI : 10.1002/eji.1830160212.Procedures for Studying Binding of Interferon to Mouse Cells
M. Aguet
Interferons Part C; 1986. p. 321 - 325. Binding and cross-linking of recombinant mouse interferon-gamma to receptors in mouse leukemic L1210 cells; interferon-gamma internalization and receptor down-regulation
J. Wietzerbin; C. Gaudelet; M. Aguet; E. Falcoff
The Journal of Immunology. 1986. Qualitative Differences in Effects of Recombinant Alpha-Interferon, Interferon-Beta and Gamma-Interferon on Human Peripheral-Blood Leukocytes Invitro
C. Billard; D. Ferbus; J. P. Kolb; F. Rosa; J. Y. Perrot
et al.
Annales De L Institut Pasteur-Immunology. 1986. DOI : 10.1016/S0771-050X(86)80045-6.Treatment of hairy cell leukemia with recombinant alpha interferon: II. In vivo down-regulation of alpha interferon receptors on tumor cells
C. Billard; F. Sigaux; S. Castaigne; F. Valensi; G. Flandrin
et al.
Blood. 1986. DOI : 10.1182/blood.V67.3.821.821.[Circulating interferon in patients with systemic lupus erythematosus. A prospective study]
C. Dudli; V. Kaiser; M. Aguet; H. Joller; W. I. Pichler
et al.
Schweizerische Medizinische Wochenschrift. 1986. Treatment of hairy cell leukemia with recombinant alpha interferon: I. Quantitative study of bone marrow changes during the first months of treatment
G. Flandrin; F. Sigaux; S. Castaigne; C. Billard; M. Aguet
et al.
Blood. 1986. DOI : 10.1182/blood.V67.3.817.817.Absence of detectable serum interferon in acute and chronic viral hepatitis
M. Pirovino; M. Aguet; M. Huber; J. Altorfer; M. Schmid
Hepatology. 1986. DOI : 10.1002/hep.1840060416.125I-labelled human interferons alpha, beta and gamma: comparative receptor-binding data
G. Merlin; E. Falcoff; M. Aguet
Journal of General Virology. 1985. DOI : 10.1099/0022-1317-66-5-1149.Receptor dynamics of closely related ligands: 'fast' and 'slow' interferons
G. Uze; K. E. Mogensen; M. Aguet
EMBO Journal. 1985. DOI : 10.1002/j.1460-2075.1985.tb02318.x.A crystalline synthetic peptide representing the epitope of a monoclonal antibody raised against synthetic interferon-alpha 1 fragment 111-166
M. Aguet; P. Salgam; B. Gutte; H. Arnheiter
European Journal of Biochemistry. 1985. DOI : 10.1111/j.1432-1033.1985.tb08705.x.[Interferon production in acute virus hepatitis]
M. Pirovino; M. Aguet; M. Huber; J. Altorfer; M. Schmid
Leber Magen Darm. 1984. Various human interferon alpha subclasses cross-react with common receptors: their binding affinities correlate with their specific biological activities
M. Aguet; M. Grobke; P. Dreiding
Virology. 1984. DOI : 10.1016/0042-6822(84)90105-3.Interferon receptors
M. Aguet; K. E. Mogensen
Interferon. 1983. High-affinity binding of 125I-labeled mouse interferon to a specific cell surface receptor. IV. Mouse gamma interferon and cholera toxin do not compete for the common receptor site of alpha / beta interferon
M. Aguet; F. Belardelli; B. Blanchard; F. Marcucci; I. Gresser
Virology. 1982. DOI : 10.1016/0042-6822(82)90497-4.Antigenic correlations between components of C243 and L cell interferons
Y. Kawade; M. Aguet; M. G. Tovey
Antiviral Res. 1982. DOI : 10.1016/0166-3542(82)90017-1.Prevention of interferon-induced augmentation of cellular antitumor effector mechanisms by phorbol esters
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Cancer Research. 1982. High affinity binding of 125I-Labeled mouse interferon to a specific cell surface receptor. II. Analysis of binding properties
M. Aguet; B. Blanchard
Virology. 1981. DOI : 10.1016/0042-6822(81)90108-2.Electrophoretically pure mouse interferon inhibits growth, induces liver and kidney lesions, and kills suckling mice
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American Journal of Pathology. 1981. Enhancement of Fc gamma receptor expression in interferon-treated mice
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European Journal of Immunology. 1981. DOI : 10.1002/eji.1830111114.Binding of 125I-labelled human alpha interferon to human lymphoid cells
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International Journal of Cancer. 1981. DOI : 10.1002/ijc.2910280508.Specific high-affinity binding of 125I-labeled mouse interferon to interfevon resistant embryonal carcinoma cells in vitro
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Virology. 1981. DOI : 10.1016/0042-6822(81)90241-5.COMPUTER MODEL AHD IMPULSE CURRENT INJECTIONS FOR OPTIMUM HEMP PROTECTION OF CABLES
M. Aguet; P. Blech; M. Ianovici; C. C. Lin
1981. 4 Symposium and Technical Exhibition on Electromagnetic Compatibility, Zurich, Zurich, Switzerland, 1981-03-10 - 1981-03-12. p. 233 - 237. DOI : 10.23919/EMC.1981.10798762.Interferon enhances the expression of Fc gamma receptors
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The Journal of Immunology. 1980. High-affinity binding of 125I-labelled mouse interferon to a specific cell surface receptor
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Nature. 1980. DOI : 10.1038/284459a0.Transient Electromagnetic-Field Coupling to Long Shielded Cables
M. Aguet; M. Ianovici; C. C. Lin
IEEE Transactions on Electromagnetic Compatibility. 1980. DOI : 10.1109/TEMC.1980.303867.IMPULSE WAVE ATTENUATION FACTOR OF SHIELDING CAGES
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M. Aguet; T. Bachi
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T. Bachi; M. Aguet; C. Howe
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Enseignement et PhD
A dirigé les thèses EPFL de
Norbert Wiedemann, Andreas Eduard Moor
