Mykhailo Batiuk
EPFL SV BMI UPGRAEFF
AI 2135 (Bâtiment AI)
Station 19
CH-1015 Lausanne
Web site: Web site: https://graefflab.epfl.ch/
Fields of expertise
Biography
I obtained my PhD (2012-2018) in KU Leuven/VIB, Belgium where I investigated astrocyte heterogeneity using single cell transcriptomics. During this period I developed tools to acutely and specifically isolate astrocytes from adult brain and identified five astrocyte subtypes in the cortex and hippocampus of mouse brain expanding previous understanding of astrocyte variability.Following my PhD, I did my first post-doc in the lab of Konstantin Khodosevich at BRIC, Copenhagen University (2018-2021) where I used single nuclei/spatial transcriptomics and identified neuronal perturbations involved in human schizophrenia. During this period I also managed single cell sequencing core facility and trained researchers to use single cell/spatial genomics tools.
Since mid 2021 I am a post-doctoral researcher in Johannes Gräff lab at EPFL. Here I combine my previous expertise in single cell genomics, psychiatry, and neuron/glia research to decipher epigenetic bases of traumatic memory.
Professional course
Post-doc
Investigation of traumatic memory using single cell genomics
SV, BMI, EPFL
15/06/2021 - ongoing
Post-doc
Investigation of human brain disorders (schizophrenia and epilepsy) using single cell and spatial transcriptomics.
BRIC, Copenhagen University, Denmark
1/12/2018 - 31/05/2021
PhD Student
Investigation of astrocyte heterogeneity using single cell transcriptomics.
VIB, KU Leuven, Belgium
1/10/2012 - 31/03/2018
Education
PhD
PhD, Doctoral School of Biomedical Sciences
KU Leuven, Belgium
1/10/2012 - 19/11/2018
MSc
Master's Degree in Biochemistry and Molecular Biology (Cum Laude)
Taras Shevchenko National Uniersity of Kyiv
1/09/2010 - 31/05/2012
BSc
Bachelor's Degree in Biology (Cum Laude)
Taras Shevchenko National Uniersity of Kyiv
1/09/2006 - 30/06/2010
Publications
Selected publications
| Mykhailo Y Batiuk, Teadora Tyler, Katarina Dragicevic, Shenglin Mei, Rasmus Rydbirk, Viktor Petukhov, Ruslan Deviatiiarov, Dora Sedmak, Erzsebet Frank, Virginia Feher, Nikola Habek, Qiwen Hu, Anna Igolkina, Lilla Roszik, Ulrich Pfisterer, Diego Garcia-Gonzalez, Zdravko Petanjek, Istvan Adorjan, Peter V Kharchenko, Konstantin Khodosevich Science Advances, 2022 |
Upper cortical layer–driven network impairment in schizophrenia |
| Mykhailo Y Batiuk, Araks Martirosyan, Jérôme Wahis, Filip de Vin, Catherine Marneffe, Carola Kusserow, Jordan Koeppen, João Filipe Viana, João Filipe Oliveira, Thierry Voet, Chris P Ponting, T Grant Belgard, Matthew G Holt Nature Communications, 2020 |
Identification of region-specific astrocyte subtypes at single cell resolution |
| Mykhailo Y Batiuk, Filip de Vin, Sandra I Duqué, Chen Li, Takashi Saito, Takaomi Saido, Mark Fiers, T Grant Belgard, Matthew G Holt Journal of Biological Chemistry, 2017 |
An immunoaffinity-based method for isolating ultrapure adult astrocytes based on ATP1B2 targeting by the ACSA-2 antibody |
| Edwards-Faret G, de Vin F, Slezak M, Gollenbeck L, Karaman R, Shinmyo Y, Batiuk M Y, Pando C M, Urschitz J, Rincon M Y, Moisyadi S, Schnütgen F, Kawasaki H, Schmucker D & Holt M G Neuroscience, 2022 |
New Technical Approach for Cross-species Examination of Neuronal Wiring and Adult Neuron-glia Functions |
| Ulrich Pfisterer, Viktor Petukhov, Samuel Demharter, Johanna Meichsner, Jonatan J Thompson, Mykhailo Y Batiuk, Andrea Asenjo-Martinez, Navneet A Vasistha, Ashish Thakur, Jens Mikkelsen, Istvan Adorjan, Lars H Pinborg, Tune H Pers, Jakob von Engelhardt, Peter V Kharchenko, Konstantin Khodosevich Nature Communications, 2020 |
Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis |
| Omer Ali Bayraktar, Theresa Bartels, Staffan Holmqvist, Vitalii Kleshchevnikov, Araks Martirosyan, Damon Polioudakis, Lucile Ben Haim, Adam M H Young, Mykhailo Y Batiuk, Kirti Prakash, Alexander Brown, Kenny Roberts, Mercedes F Paredes, Riki Kawaguchi, John H Stockley, Khalida Sabeur, Sandra M Chang, Eric Huang, Peter Hutchinson, Erik M Ullian, Martin Hemberg, Giovanni Coppola, Matthew G Holt, Daniel H Geschwind, David H Rowitch Nature Neuroscience, 2020 |
Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map |
| Bizhan R Sharop, Oleksii I Boldyriev, Mykhailo Y Batiuk, Nataliia L Shtefan, Yaroslav M Shuba Epilepsy Research, 2016 |
Compensatory reduction of Cav3.1 expression in thalamocortical neurons of juvenile rats of WAG/Rij model of absence epilepsy |