Pierre Vogel
Nationalité: Swiss
+41 21 693 93 71
EPFL › SB › ISIC › ISIC-DIV
Textbooks
Vogel, P.; Houk, K. N. Organic Chemistry; Theory, Reactivity and Mechanisms in Modern Synthesis, Foreword by Grubbs, Robert H. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2019, pp 1-1352. ISBN 978-3-527-34532-8 (hardcover); ISBN 978-3-527-81925-6 (ePDF), ISBN 978-3-527-81927-0 (ePub) "C:\Users\pvogel\OneDrive - epfl.ch\Bureau\CD15651-Vogel Flyer-Wiley-GlobalA4-2pp-Final print Ready-Nomarks.pdf"
Vogel, P. Chimie Organique. Méthodes et Modèles. Préface de Prof.Jean-Marie Lehn. DeBoeck Univerité, Bruxelles,Paris, 1997, pp. 1-1432, ISBN 2-8041-2620-X.
Vogel, P. Carbocation Chemistry, Elsevier, Amsterdam, 1985, pp. 1-610 . ISBN 1: 444425225/ISBN 13: 9780444425225
Patents
1. Preparation of 4-amino-1-alkoxynaphthalene IDO inhibitors for cancer treatment. Roehrig, Ute; Loay, Awad; Michielin, Olivier; Van Den Eynde, Benoit; Pilotte, Luc; Stroobant, Vincent; Larrieu, Pierre; Vogel, Pierre; Zoete, Vincent; Assignee: Ludwig Institute for Cancer Research Ltd, USA, Patent Apr 21, 2011, WO 2011045340 A1.
2. Preparation of 4-iminonaphthalenones as IDO inhibitors. Roehrig, Ute; Loay, Awad; Michielin, Olivier; Van Den Eynde, Benoit; Pilotte, Luc; Stroobant, Vincent; Larrieu, Pierre; Vogel, Pierre Zoete, Vincent; Assignee: Ludwig Institute for Cancer Research Ltd, USA, Patent Apr 21, 2011, WO 2011045341 A1.
3. Preparation of piperidine derivatives for the treatment of pancreatic cancers. Vogel, Pierre; Duchosal, Michel; Aimable, Nahimana; Robina, Inmaculada; Mollinedo, Faustino; Nencioni, Alessio. Assignee: Centre Hospitalier Universitaire Vaudois (CHUV), Switzerland; Consejo Superior de Investigaciones Cientificas (CSIC), Spain. Patent Feb 8, 2018, WO 2018024907 A1.
Publications représentatives
Expeditions Asymmetric Synthesis of a Stereoheptad Corresponding to the C(19)-C(27)-Ansa Chain of Rifamycins: Formal Total Synthesis of Rifamycin S.
Turks, M.; Huang, X.; Vogel, P.
Published in Chem. Eur. J. 2005, 11, 465. in
Polysulfones: solid organic catalysts for the chemoselective cleavage of methyl-substituted allyl ethers under neutral conditions.
Markovic, D.; Steunenberg, P.; Ekstrand, M.; Vogel, P.
Published in J. Chem. Soc., Chem. Commun. 2004, 2444. in
Sulfur Dioxide Mediated One-Pot, Three- and Four-Component Syntheses of Polyfunctional Sulfonamides and Sulfonic Esters: Study of the Stereoselectivity of the Ene Reaction of Sulfur Dioxide.
Bouchez, L.; Dubbaka, S. R.; Turks, M.; Vogel, P.
Published in Journal of Organic chemsitry, 2004, 69(19), 6413-6418. in
First Asymmetric Synthesis of the Cyclohexanone Subunit of Baconipyrones A and B. Revision of Its Structure.
Turks,M.; Murcia, M. C.; Scopelliti,R.; Vogel, P.
Published in Organic Letters, 2004, 6(18), 3031-3034. in
Synthesis of D- and L-2,3-trans-3,4-cis-4,5-trans-3,4-Dihydroxy-5-hydroxymethylproline and Tripeptides Containing Them.
Moreno Vargas, A. J.; Robina, I.; Petricci, E.; Vogel, P.
Published in Journal of Organic Chemistry, 2004, 69(13), 4487-4491. in
Synthesis of Long-Chain Polyketide Fragments by Reaction of 1,3-Dioxy-1,3-dienes with Allylsilanes: Umpolung with Sulfur Dioxide.
Turks, M.; Fonquerne, F.; Vogel, P.
Published in Organic Letters, 2004, 6(6), 1053-1056 in
Palladium-Catalyzed Stille Cross-Couplings of Sulfonyl Chlorides and Organostannanes.
Dubbaka, S. R.; Vogel, P.
Published in Journal of the American Chemical Society. 2004, 125(59), 15292-15293. in
An expeditous, on-iterative, and asymmetric synthesis of 3,5,7,9,11,13,15-heptahydroxypentadecanals.
Gerber, S.; Vogel, P.
Published in European Journal of Organic Chemistry, 2003, (15), 2959-2963. in
Ab Initio and Experimental Studies on the Hetero-Diels-Alder and Cheletropic Additions of Sulfur Dioxide to (E)-1-Methoxybutadiene: A Mechanism Involving Three Molecules of SO2.
Monnat, F.; Vogel, P.; Rayon, V. M.; Sordo, J. A.
Published in J. Org. Chem., 2002, 67, 1882-1889. in
Total Asymmetric Synthesis of a New 9,12-Anhydroerythronolide Aglycone.
Gerber-Lemaire, S.; Ainge, S. W.; Glanzmann, C.; Vogel, P.
Published in Helv. Chim. Acta. 2002, 85, 417-430. in
An efficient Combinatorial Method for the discovery of Glycosidase Inhibitors.
Gerber-Lemaire, S.; Poposycz, F.; Rodriguez-Garcia, E.; Carmona-Asenjo, A. T.; Robina, I.; Vogel, P.
Published in ChemBioChem, 2002, 3(5), 466-470. in
A New, Non-Iterative Asymmetric Synthesis of Long.Chain, 1,3-Polyols.
Schwenter, M.-E.; Vogel, P.
Published in Chem. Eur. J., 2000, 6, 4091-4103. in
The C-Disaccharide α-C(1→3)-Mannopyranoside of N-Acetylgalactosamine is an Inhibitor of Glycohydrolases and of Human α-1, 3-Fucosyltransferase VI. Its Epimer α- (1→3)-Mannopyranoside of N-Acetylosamine Is Not.
Pasquarello, C.; Picasso, S.; Demange, R.; Malissard, M.; Berger, E.G.; Vogel, P.
Published in The Journal of Organic Chemistry, 2000, 65(14), 4251-4260. in
Synthesis of a C29-C51 Subunit of Spongistatin 1(Altohyrtin A) Starting from (R)-3-Benzyloxy-2-methylpropan-1-ol.
Lemaire-Audoire, S.; Vogel, P.
Published in J. Org. Chem., 2000, 65, 3346-3356. in
A New Asymmetric Carbon-Carbon Bond Forming Reaaction: Four-Coponent Stereoselective Synthesis of 8Z)-4,6-Dihydroxy-3-methylalk-2-enyl Methyl Sulfones.
Narkevitch, V.; Schenk, K.; Vogel, P.
Published in Angew. Chem. Int. Ed., 2000, 39, 1806-1808. in
Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity,
Borcard, Francoise; Baud, Matthias; Bello, Claudia; Dal Bello, Giovanna; Grossi, Francesco; Pronzato, Paolo; Cea, Michele; Nencioni, Alessio; Vogel, Pierre
Published in Bioorg. Med. Chem. Letters 2010, 20, 5353-5356 in 2010
Rational Design of Indoleamine 2,3-Dioxygenase Inhibitors
Roehrig, Ute F.; Awad, Loay; Grosdidier, Aurelien; Larrieu, Pierre; Stroobant, Vincent; Colau, Didier; Cerundolo, Vincenzo; Simpson, Andrew J.; Vogel, Pierre; Van den Eynde, Benoit J.; Zoete, Vincent; Michielin, Olivier.
Published in J. Med. Chem. 2010, 53, 1172-1189 in 2010
Anti-cancer activity of 5-O-alkyl 1,4-imino-1,4-dideoxyribitols
Bello, Claudia; Dal Bello, Giovanna; Cea, Michele; Nahimana, Aimable; Aubry, Dominique; Garuti, Anna; Motta, Giulia; Moran, Eva; Fruscione, Floriana; Pronzato, Paolo; Grossi, Francesco; Patrone, Franco; Ballestrero, Alberto; Dupuis, Marc; Sordat, Bernard; Zimmermann, Kaspar; Loretan, Jacqueline; Wartmann, Markus; Duchosal, Michel A.; Nencioni, Alessio; Vogel, Pierre.
Published in Bioorg. Med. Chem. 2011, 19, 7720-7727. https://doi.org/10.1016/j.bmc.2011.07.053 in 2011
A C-Linked Disaccharide Analogue of Thomsen-Friedenreich Epitope Induces a Strong Immune Response in Mice.
Awad, Loay; Madani, Rime; Gillig, Annabelle; Kolympadi, Maria; Philgren, Maria; Muhs, Andreas; Gerard, Catherine; Vogel, Pierre.
Published in Chem. Eur. J. 2012, 18, 8578-8582. https://doi.org/10.1002/chem.201200364 in 2012
Synthesis of branched seven-membered 1-N-iminosugars and their evaluation as glycosidase inhibitors.
Li, Hongqing; Zhang, Yongmin; Favre, Sylvain; Vogel, Pierre; Sollogoub, Matthieu; Bleriot, Yves.
Published in Carbohydrate Research 2012, 356, 110-114. https://doi.org/10.1016/j.carres.2011.10.039 in 2012
Rational Design of 4-Aryl-1,2,3-Triazoles for Indoleamine 2,3-Dioxygenase 1 Inhibition
Roehrig, Ute F.; Majjigapu, Somi Reddy; Grosdidier, Aurelien; Bron, Sylvian; Stroobant, Vincent; Pilotte, Luc; Colau, Didier; Vogel, Pierre; Van den Eynde, Benoit J.; Zoete, Vincent; Michielin, Olivier.
Published in J. Med. Chem. 2012, 55, 5270-5290. httpds://doi.org/10.1021/jm300260v in 2026
Synthesis of 2-(1-aminocyclopropyl)pyrrolidine-3,4-diol derivatives applying titanium-mediated reaction conditions.
Declerck, Delphine; Nhien, Albert Nguyen Van; Josse, Solen; Szymoniak, Jan; Bertus, Philippe; Bello, Claudia; Vogel, Pierre; Postel, Denis.
Published in Tetrahedron 2012, 68, 1802-1809. https://doi.org/10.1016/j.tet.2011.12.024 in 2012
Synthesis of a C-Iminoribofuranoside Analog of the Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitor FK866.
Gillig, Annabelle; Majjigapu, Somi Reddy; Sordat, Bernard; Vogel, Pierre.
Published in Helv. Chim. Acta 2012, 95, 34-42. https://doi.org/10.1002/hlca.201100415 in 2012
Amide Formation in One Pot from Carboxylic Acids and Amines via Carboxyl and Sulfinyl Mixed Anhydrides.
Zambron, Bartosz K.; Dubbaka, Srinivas R.; Markovic, Dean; Moreno-Clavijo, Elena; Vogel, Pierre.
Published in Org. Letters 2013, 15, 2550-2553. https://doi.org/10.1021/ol401053y in 2013
Amides in One Pot from Carboxylic Acids and Amines via Sulfinylamides.
Bai, Jianfei; Zambron, Bartosz K.; Vogel, Pierre.
Published in Org. Letters 2014, 16 (2), 604-607. https://doi.org/10.1021/ol403508j in 2014
Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors
Roehrig, Ute F.; Majjigapu, Somi Reddy; Chambon, Marc; Bron, Sylvian; Pilotte, Luc; Colau, Didier; Van den Eynde, Benoit J.; Turcatti, Gerardo; Vogel, Pierre; Zoete, Vincent; Michielin, Olivier.
Published in Eur. J. Med. Chem. 2014, 84, 284-301. https://doi.org/10.1016/j.ejmech.2014.06.078 in 2014
Synthesis of pyrrolidine 3,4-diol derivatives with anticancer activity on pancreatic tumor cells.
Steimer, Frederic; Carmona, Ana T.; Moreno-Vargas, Antonio J.; Caffa, Irene; Cea, Michele; Montecucco, Fabrizio; Nencioni, Alessio;Vogel, Pierre; Robina, Inmaculada.
Published in Heterocycles 2014, 88 (2), 1445-1464. in 2014
A critical role of autophagy in antileukemia/ lymphoma effects of APO866, an inhibitor of NAD biosynthesis.
Ginet, Vanessa; Puyal, Julien; Rummel, Coralie; Aubry, Dominique; Breton, Caroline; Cloux, Anne-Julie; Majjigapu, Somi R.; Sordat, Bernard; Vogel, Pierre; Bruzzone, Santina; Nencioni, Alessio; Duchosal, Miechel A.; Nahimana, Aimable.
Published in Autophagy, 2014, 10(4), 603–617. https://doi.org/10.4161/auto.27722 in 2014
The anti-lymphoma activity of APO866, an inhibitor of nicotinamide adenine dinucleotide biosynthesis, is potentialized when used in combination with anti-CD20 antibody
Nahimana, Aimable; Aubry, Dominique; Breton, Caroline S.; Majjigapu, Somi R.; Sordat, Bernard; Vogel, Pierre; Duchosal, Michel A.
Published in Leukemia & Lymphoma 2014, 55 (9), 2141-2150. https://doi.org/10.3109/10428194.2013.869325 in 2014
Challenges in the Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.
Roehrig, Ute F.; Majjigapu, Somi Reddy; Vogel, Pierre; Zoete, Vincent; Michielin, Olivier.
Published in J. Med. Chem. 2015, 58 (24), 9421-9437. https://doi.ord/10.1021/acs.jmedchem.5b00326 in 2015
1,2,3-Triazoles as inhibitors of indoleamine 2,3-dioxygenase 2 (IDO2).
Roehrig, Ute F.; Majjigapu, Somi Reddy; Caldelari, Daniela; Dilek, Nahzli; Reichenbach, Patrick; Ascencao, Kelly; Irving, Melita; Coukos, George; Vogel, Pierre; Zoete, Vincent; Michielin, Olivier.
Published in Bioorg. Med. Chem. Lett. 2016, 26 (17), 4330-4333. https://doi.org/10.1016/j.bmcl.2016.07.031 in 2016
Induction of cell killing and autophagy by amphiphilic pyrrolidine derivatives on human pancreatic cancer cells
Bello, Claudia; Bai, Jianfei; Zambron, Bartosz K.; Elias-Rodriguez, Pilar; Gajate, Consuelo; Robina, Inmaculada; Caffa, Irene; Cea, Michele; Montecucco, Fabrizio; Nencioni, Alessio; Nahimana, Aimable; Aubry, Dominique; Breton, Caroline; Duchosal, Michel A.; Mollinedo, Faustino; Vogel, Pierre
Published in Eur. J. Med. Chem. 2018, 150, 457-478. https://doi.org/10.1016/j.ejmech.2018.02.086 in 2018
Inhibition Mechanisms of Indoleamine 2,3-Dioxygenase 1 (IDO1).
Roehrig, Ute F.; Reynaud, Aline; Majjigapu, Somi Reddy; Vogel, Pierre; Pojer, Florence; Zoete, Vincent.
Published in J. Med. Chem. 2019, 62 (19), 8784-8795. https://doi.org/10.1021/acs.jmedchem.9b00942 in 2019
Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.
Röhrig, Ute; Majjigapu, Somi Reddy; Reynaud, Aline; Pojer, Florence; Dilek, Nahzli; Reichenbach, Patrick; Ascencao, Kelly; Irving, Melita; Coukos, George; Vogel, Pierre; Michielin, Oliver; Zoete, Vincent.
Published in .J. Med. Chem. 2021, 64(4), 2205-2227. https://doi.org/10.1021/acs.jmedchem.0c01968 in 2021
Identification of new FK866 analogues with potent anticancer activity against pancreatic cancer.
Bai, Jianfei; Majjigapu, Sordat, Bernard; Poty, Sophie; Vogel, Pierre; Elias-Rodriguez, Pilar; Moreno-Vargas, Antonio, J.; Carmona, Ana. T.; Caffa, Irene; Ghanem, Moustafa; Khalifa, Amr; Robina, Inmaculada; Cajate, Consuelo; Mollinedo, Faustino; Nahimana, Aimable; Duchosal, Michel; Nencioni, Alessio.
Published in Eur. J. Med. Chem. 2022, 239, article no. 114504, pp. 1-11. https://doi.org/10.1016/j.ejmech.2022.114504 in 2022
Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors
Röhrig, Ute, F.; Majjigapu, Somi, R.; Vogel, Pierre; Reynaud, Aline; Pojer, Florence; Dilek, Nahzli; Reichenbach, Patrick; Ascenção, Kelly; Irving, Melita; Coukos, George; Michielin, Olivier; Zoete, Vincent.
Published in Journal of Enzyme Inhibition and Medicinal Chemistry, 2022, 37(1), 1773-1811, https://doi.org/10.1080/14756366.2022.2089665. in 2022
Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies.
Biniecka, P.; Matsumoto, S.; Belotti, A.; Joussot, J.; Bai, J. F.; Majjigapu, S. R.; Thoueille, P.; Spaggiari, D.; Desfontaine, V.; Piacente, F.; Bruzzone, S.; Cea, M.; Decosterd, L. A.; Vogel, P.; Nencioni, A.; Duchosal, M. A.; Nahimana, A.
Published in Molecules 2023, 28, article nb. 1897, pp. 1-23. https://doi.org/10.3390/molecules28041897 in 2023
Organocatalysis: fundamentals and comparisons to metal and enzyme catalysis,
Vogel, Pierre; Lam, Yu-hong; Simon, Adam; Houk, Kendall N.
Published in Catalysts 2016, 6 (9), article nb, 128, pp. 1-65. https://doi.org/10.3390/catal6090128 in 2016
Expeditious Asymmetric Synthesis of Polypropionates Relying on Sulfur Dioxide-Induced C-C Bond Forming Reactions
Vogel, Pierre; Sordo Gonzalo, Jose Angel.
Published in Catalysts 2021, 11(11), article nb. 1267, pp.1-20. https://doi.org/10.3390/catal11111267 in 2021
Organic Chemistry and Synthesis Rely More and More upon Catalysts.
Vogel, Pierre; Houk, Kendall N.
Published in Catalysts 2022, 12(7), article no. 758, pp. 1-31. https://doi.org/10.3390/catal12070758 in 2022
Asymmetric Bio- and Organocatalysis: Historical Aspects and Concepts.
Vogel, Pierre.
Published in Catalysts 2026, 6, article nb. 131, pp. 1-142. https://doi.org/10.3390/catal16020131. Link: https://www.mdpi.com/2073-4344/16/2/131 in 2026
Total Synthei and Determinaion f the Absolte Configuration of (-)-Dolabriferol
Laclef, S.; Turk, M.; Vogel, P.
Published in Angew. Chem. Int. Ed. 2010, 49(4), 8525-8527 in 2010
Synthesis and Applications of Silyl 2-Methylprop-2-ene-1-sulfinates in Preparative Silylation and GC-Derivatization actions of Polyols and Carbohydrates s
Markovic, D.; Tchawou, W. A.; Novosjolova, I.; LaClef, S.; Stepanovs, D.; Turks, M.; Vogel. P.
Published in Chem. Eur. J. 2016, 22(12), 4196-4205 in 2016
The norbornene mistery revealed
Steinmann, S. N.; Vogel, P.; Mo, Y.; Corminboeuf, C.
Published in Chem. Commun. 2011, 47(1), 227-229 in 2011
Enseignement et PhD
A dirigé les thèses EPFL de
Hervé Mosimann, Marc-Etienne Schwenter, Patrick Gerber, Sophie Megevand, Raynald Demange, Kai Torsten Meilert, Frédéric Carrel, Florence Popowycz, Laure Bouchez, Xiaogen Huang, Loay Awad, Eliazar Rodriguez Garcia, Peter Steunenberg, Dean Markovic, Maris Turks, Cotinica Craita, Freddy Fonquerne, Srinivas Reddy Dubbaka, Sylvain Favre, Claudia Bello, Chandra Mouleeswara Rao Volla, Sylvain Claude Laclef, Annabelle Gillig, Christopher Flowers, Claudia Jana Exner, Maria Kolympadi