Raphaël Doenlen

EPFL SV CPG-GE
SV 1540 (Bâtiment SV)
Station 19
1015 Lausanne

Formation

Master

| Neurosciences

2004 – 2004 University of Louis Pasteur, Strasbourg (France)

Master

| Psychopharmacologie

2005 – 2005 University of Bordeaux 1 (France)

Doctorat

| Sciences de la Vie - Neuroimmunologie

2005 – 2008 Swiss Federal Institute of Technology, ETH Zürich (Switzerland)
Dirigée par Principal supervisor: Prof. Joram Feldon, Institute of Behavioural Neurobiology, ETH Zürich (Switzerland)Co-supervisor: Prof. Manfred Schedlowski, Division of Medical Psychology and Behavioral Immunobiology, Medical Faculty of Duisburg-Essen (Germany)

Investigations on the Ability of the Insular Cortex to Process Peripheral Immunosuppression

J. BihoracY. SalemL. LückemannM. SchedlowskiR. Doenlen  et al.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2024. DOI : 10.1007/s11481-024-10143-9.

Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100 Gy/s

P. Montay-GruelK. PeterssonM. JaccardG. BoivinJ.-F. Germond  et al.

2017. 15th International Wolfsberg Meeting on Molecular Radiation Biology/Oncology, SWITZERLAND, JUN 17-19, 2017. p. 365 - 369. DOI : 10.1016/j.radonc.2017.05.003.

Acute systemic rapamycin induces neurobehavioral alterations in rats

M. HadamitzkyA. HerringK. KeyvaniR. DoenlenU. Krügel  et al.

Behavioural brain research. 2014. DOI : 10.1016/j.bbr.2014.06.056.

Neurobehavioural activation during peripheral immunosuppression

G. Pacheco-LópezR. DoenlenU. KrügelM. ArnoldT. Wirth  et al.

The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). 2013. DOI : 10.1017/S1461145711001799.

Amygdaloid Signature of Peripheral Immune Activation by Bacterial Lipopolysaccharide or Staphylococcal Enterotoxin B

G. PragerM. HadamitzkyA. EnglerR. DoenlenT. Wirth  et al.

Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2013. DOI : 10.1007/s11481-012-9373-0.

Acute amygdaloid response to systemic inflammation

H. EnglerR. DoenlenA. EnglerC. RietherG. Prager  et al.

Brain, behavior, and immunity. 2011. DOI : 10.1016/j.bbi.2011.04.005.

Electrical activity in rat cortico-limbic structures after single or repeated administration of lipopolysaccharide or staphylococcal enterotoxin B

R. DoenlenU. KrügelT. WirthC. RietherA. Engler  et al.

Proceedings. Biological sciences / The Royal Society. 2010. DOI : 10.1098/rspb.2010.2040.

Stimulation of β₂-adrenergic receptors inhibits calcineurin activity in CD4(+) T cells via PKA-AKAP interaction

C. RietherA. KavelaarsT. WirthG. Pacheco-LópezR. Doenlen  et al.

Brain, behavior, and immunity. 2010. DOI : 10.1016/j.bbi.2010.07.248.

Time-dependent alterations of peripheral immune parameters after nigrostriatal dopamine depletion in a rat model of Parkinson's disease

H. EnglerR. DoenlenC. RietherA. EnglerM.-B. Niemi  et al.

Brain, behavior, and immunity. 2009. DOI : 10.1016/j.bbi.2009.01.018.

Chemical destruction of brain noradrenergic neurons affects splenic cytokine production

H. EnglerR. DoenlenC. RietherA. EnglerH. O. Besedovsky  et al.

Journal of neuroimmunology. 2009. DOI : 10.1016/j.jneuroim.2009.12.001.

Calcineurin inhibition in splenocytes induced by pavlovian conditioning

G. Pacheco-LópezC. RietherR. DoenlenH. EnglerM.-B. Niemi  et al.

The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2008. DOI : 10.1096/fj.08-115683.

Assessment of neurobehavioural traits under gnotobiotic conditions: an approach for multiple analyses in the same mouse

A. RutschM. IachizziJ. KirundiJ. B. KantsjöA. L. Planchette  et al.

Brain, behavior, and immunity. 2025. DOI : 10.1016/j.bbi.2025.106084.

The metabolic footprint of aging in mice

R. H. HoutkooperC. ArgmannS. M. HoutenC. CantóE. H. Jeninga  et al.

Scientific Reports. 2011. DOI : 10.1038/srep00134.

Behavioural conditioning of immune functions: how the central nervous system controls peripheral immune responses by evoking associative learning processes

C. RietherR. DoenlenG. Pacheco-LópezM.-B. NiemiA. Engler  et al.

Reviews in the neurosciences. 2008. DOI : 10.1515/REVNEURO.2008.19.1.1.

Fingerprints of neural activity after peripheral immune challenges

R. Doenlen

ETH Zürich, 2008. DOI : 10.3929/ethz-a-005806976.

Enseignement et PhD

Cours

Methods: from disease models to therapy

BIOENG-518

Ce cours décrira les méthodes qui sont à la base des approches translationnelles depuis la génération et la caractérisation des modèles des maladies jusqu'aux applications thérapeutiques. Les bases théoriques seront complétées par des rotations pratiques dans les plateformes technologiques.