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Tamar Kohn

EPFL ENAC IIE LEV
GR A0 402 (Bâtiment GR)
Station 2
1015 Lausanne

EPFL ENAC IIE LEV
GR A0 402 (Bâtiment GR)
Station 2
1015 Lausanne

EPFL ENAC IIE LEV
GR A0 402 (Bâtiment GR)
Station 2
1015 Lausanne

EPFL ENAC IIE LEV
GR A0 402 (Bâtiment GR)
Station 2
1015 Lausanne

Expertise

Disinfection
Waterborne pathogens
Airborne pathogens
Environmental virology
Sanitation and hygiene

Mission

We study the fate of viruses outside the host, mostly in water, sometimes in air.
2023 - present Full Professor, EPFL
2014 - 2023 Associate Professor, EPFL
2014 - present Adjunct researcher, Eawag
2007 - 2013 Assistant Professor, EPFL
2004 - 2006 Postdoctoral researcher, UC Berkeley
2000 - 2004 PhD, Environmental Engineering, Johns Hopkins University
1999 Diploma, Environmental Sciences, ETHZ

Journal articles (last 3 years)

2025

Lognormal distributions capture site-specific variability in enteric virus concentrations in wastewater

C. LiT. KohnS. ToriiH. K. WynnA. Devaux  et al.

Environmental Science: Water Research & Technology. 2025. DOI : 10.1039/d5ew00286a.

Performance and characteristics of three digital PCR platforms for detection and quantification of viral targets in wastewater

M. PittonJ. C. RuschS. ToriiL. CaduffP. Schmidhalter  et al.

Journal of Applied Microbiology. 2025. DOI : 10.1093/jambio/lxaf243.

Unraveling the Inactivation Mechanisms of Human Adenovirus 2 in Sunlight Disinfection: Synergism between Direct and Indirect Pathways

S. ShinY. LeeT. Kohn

Environmental Science & Technology. 2025. DOI : 10.1021/acs.est.5c06149.

Comparative characterization of bronchial and nasal mucus reveals key determinants of influenza A virus inhibition

M. PohlK. ViolakiL. LiuE. GaggioliI. Glas  et al.

mSphere. 2025. DOI : 10.1128/msphere.00365-25.

Estimated transmission dynamics of SARS-CoV-2 variants from wastewater are unbiased and robust to differential shedding

D. DreifussJ. HuismanJ. RuschL. CaduffP. Ganesanandamoorthy  et al.

Nature Communications. 2025. DOI : 10.1038/s41467-025-62790-y.

Transmission dynamics of Norovirus GII and Enterovirus in Switzerland during the COVID-19 pandemic (2021-2022) as evidenced in wastewater

J. HuismanS. ToriiH. K. WynnC. GanI. Voellmy  et al.

Epidemics. 2025. DOI : 10.1016/j.epidem.2025.100851.

Inactivation of SARS-CoV-2 at acidic pH is driven by partial unfolding of spike

I. GlasL. ZimmermannB. LuoM. O. PohlA. G. Wrobel  et al.

Communications Biology. 2025. DOI : 10.1038/s42003-025-08514-w.

Conserved specificity of extracellular wastewater peptidases revealed by multiplex substrate profiling by mass spectrometry

N. WichmannJ. MeibomT. KohnM. Zumstein

Environmental Chemistry Letters. 2025. DOI : 10.1007/s10311-025-01834-7.

Seasonality of cyanobacteria and eukaryotes in Lake Geneva and the impacts of cyanotoxins on growth of the model ciliate Tetrahymena pyriformis

N. IsmailP. SeguinL. PricamE. JanssenT. Kohn  et al.

Aquatic Toxicology. 2025. DOI : 10.1016/j.aquatox.2025.107262.

Diversity of lake bacteria promotes human echovirus inactivation

A. RomanenkoH. PeterJ. MeibomM. BorchardtT. Kohn

Applied and Environmental Microbiology. 2025. DOI : 10.1128/aem.02366-24.

2024

Dependence of aerosol-borne influenza A virus infectivity on relative humidity and aerosol composition

G. MotosA. L. SchaubS. C. DavidL. CostaC. Terrettaz  et al.

Frontiers in Microbiology. 2024. DOI : 10.3389/fmicb.2024.1484992.

Salt Supersaturation as an Accelerator of Influenza A Virus Inactivation in 1 μL Droplets

A. SchaubB. LuoS. DavidI. GlasL. Klein  et al.

Environmental Science & Technology. 2024. DOI : 10.1021/acs.est.4c04734.

Impact of organic compounds on the stability of influenza A virus in deposited 1-μL droplets

A. L. SchaubS. C. DavidI. GlasL. KleinK. Violaki  et al.

mSphere. 2024. DOI : 10.1128/msphere.00414-24.

The early communication stages between serine proteases and enterovirus capsids in the race for viral disintegration

M.-H. CorreB. ReyS. C. DavidS. ToriiD. Chiappe  et al.

Communications Biology. 2024. DOI : 10.1038/s42003-024-06627-2.

Influence of Amino Acid Substitutions in Capsid Proteins of Coxsackievirus B5 on Free Chlorine and Thermal Inactivation

S. ToriiJ. GouttenoireK. KumarA. AntanasijevicT. Kohn  et al.

Environmental Science & Technology. 2024. DOI : 10.1021/acs.est.3c10409.

Monitoring an Emergent Pathogen at Low Incidence in Wastewater Using qPCR: Mpox in Switzerland

T. R. JulianA. J. DevauxL. BrülisauerS. ConfortiJ. C. Rusch  et al.

Food and Environmental Virology. 2024. DOI : 10.1007/s12560-024-09603-5.

Stability of influenza A virus in droplets and aerosols is heightened by the presence of commensal respiratory bacteria

S. C. DavidA. L. SchaubC. TerrettazG. MotosL. J. Costa Henriques  et al.

Journal of Virology. 2024. DOI : 10.1128/jvi.00409-24.

Comparison of Three Viral Nucleic Acid Preamplification Pipelines for Sewage Viral Metagenomics

X. Fernandez CassiT. Kohn

Food and Environmental Virology. 2024. DOI : 10.1007/s12560-024-09594-3.

Waterborne Virus Transport and Risk Assessment in Lake Geneva Under Climate Change

C. LiT. Kohn

Earth's Future. 2024. DOI : 10.1029/2023EF003831.

2023

Inactivation mechanisms of influenza A virus under pH conditions encountered in aerosol particles as revealed by whole-virus HDX-MS

S. C. DavidO. VadasI. GlasA. SchaubB. Luo  et al.

mSphere. 2023. DOI : 10.1128/msphere.00226-23.

Doctoral theses

Inactivation of influenza A virus in expiratory droplets and aerosol particles and the associated physicochemical drivers

A. L. Schaub / T. Kohn (Dir.)

Lausanne, EPFL, 2024. DOI : 10.5075/epfl-thesis-10449.

Numerical simulation of the fate, transport and public health risks of enteric viruses in Lake Geneva

C. Li / T. KohnA. J. Wüest (Dir.)

Lausanne, EPFL, 2023. DOI : 10.5075/epfl-thesis-10322.

Effect of wastewater treatment and environmental exposure on an enterovirus population

O. M. C. Hervás de Nalda-Larivé / T. Kohn (Dir.)

Lausanne, EPFL, 2022. DOI : 10.5075/epfl-thesis-8985.

Toward biocontrol of waterborne pathogens: contributions of protists to virus removal and associated mechanisms

M. N. L. Olive / T. Kohn (Dir.)

Lausanne, EPFL, 2022. DOI : 10.5075/epfl-thesis-9255.

Susceptibility of Enterovirus B strains to disinfectants and heat

S. Meister / T. Kohn (Dir.)

Lausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-9343.

Inactivation of waterborne viruses by ozone: Kinetics and mechanisms

C. Wolf / T. Kohn (Dir.)

Lausanne, EPFL, 2019. DOI : 10.5075/epfl-thesis-9370.

Virus transfer at the skin-liquid interface and its associated risks

A. K. Pitol Garcia / T. KohnT. R. Julian (Dir.)

Lausanne, EPFL, 2018. DOI : 10.5075/epfl-thesis-8961.

Genotypic, phenotypic and mechanistic insights into viruses with resistance to common water disinfectants

Q. Zhong / T. Kohn (Dir.)

Lausanne, EPFL, 2017. DOI : 10.5075/epfl-thesis-7538.

Virus inactivation mechanisms in human urine and fecal sludge

L. Decrey / T. KohnK. Udert (Dir.)

Lausanne, EPFL, 2015. DOI : 10.5075/epfl-thesis-6579.

Mechanistic insight into virus disinfection : influence of virus characteristics, solution composition and surface interactions

A. T. Sigstam / T. Kohn (Dir.)

Lausanne, EPFL, 2014. DOI : 10.5075/epfl-thesis-6166.

Virus Inactivation during Water Treatment : the Role of Virus Aggregation and the Disinfection Potential of Sunlight

M. J. Mattle / T. Kohn (Dir.)

Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5873.

Sources, Spreading and Fate of Antibiotic Resistance Genes and Resistant Bacteria in Vidy Bay, Lake Geneva, Switzerland

N. Czekalski / T. KohnH. Bürgmann (Dir.)

Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5637.

Spatio-Temporal Presence of Micropollutants and their Metabolites in Lake Geneva and Susceptibility to Direct and Indirect Photodegradation Processes

F. Bonvin / T. Kohn (Dir.)

Lausanne, EPFL, 2013. DOI : 10.5075/epfl-thesis-5677.

Virus Inactivation by Homogeneous and Heterogeneous Fenton-like Processes

J. I. Nieto Juarez / T. Kohn (Dir.)

Lausanne, EPFL, 2012. DOI : 10.5075/epfl-thesis-5295.

Teaching & PhD

Current Phd

Taylor Oran Medina, Josephine Lederballe Meibom, Vidhi Ketan Dholakia, Alissa Agerova, Hui Dong, Madeline Emma Deck

Past Phd As Director

Jessica Ivana Nieto Juarez, Michael Jon Mattle, Florence Bonvin, Nadine Czekalski, Anne Thérèse Sigstam, Loïc Decrey, Qingxia Zhong, Ana Karina Pitol Garcia, Camille Wolf, Simon Meister, Odile Hervás de Nalda-Larivé, Margot Ninon Lauren Olive, Chaojie Li, Aline Laetitia Schaub

Past Phd As Codirector

Annie Sandrine Guillaume

Courses

Environmental chemistry

ENV-200

This course provides students with an overview over the basics of environmental chemistry. This includes the chemistry of natural systems, as well as the fate of anthropogenic chemicals in natural systems. It enables students to apply general chemical concepts to natural systems.

Introduction to environmental engineering

ENV-167

Key themes in environmental science and engineering will be show-cased, with examples - from equator to the poles - including atmospheric processes and climate change, water quality, energy resources and urban development, with the amazing technologies used to study and address current challenges.