Profile picture

Dominique Pioletti

EPFL STI IBI-STI LBO
MED 3 2626 (Bâtiment MED)
Station 9
1015 Lausanne

EPFL STI IBI-GE
MED 3 2626 (Bâtiment MED)
Station 9
1015 Lausanne

EPFL STI IGM-GE
MED 3 2626 (Bâtiment MED)
Station 9
1015 Lausanne

EPFL STI DLL-STI
MED 3 1019 (Bâtiment MED)
Station 9
1015 Lausanne

Expertise

Biomechanics
Tissue Engineering
Mechano-biology

Publications représentatives

Bone tissue engineering using fetal cell therapy

D.P. Pioletti, M.O. Montjovent, P.Y. Zambelli and L. Applegate
Published in Swiss Medical Weekly, 136, 557-560 (2006) in

Journal paper and review

2025

Helmet material design for mitigating traumatic axonal injuries through AI-driven constitutive law enhancement

V. VarangesP. EghbaliN. NasrollahzadehJ. Y. FournierP. E. Bourban  et al.

Communications Engineering. 2025. DOI : 10.1038/s44172-025-00370-0.

Causal associations between scapular morphology and shoulder condition estimated with Bayesian statistics

P. EghbaliO. B. SatirF. BecceP. GoettiP. Büchler  et al.

Computer Methods and Programs in Biomedicine. 2025. DOI : 10.1016/j.cmpb.2025.108666.

Combining systemic and local osteoporosis treatments: A longitudinal in vivo microCT study in ovariectomized rats

V. A. StadelmannE. GerossierU. KettenbergerD. P. Pioletti

Bone. 2025. DOI : 10.1016/j.bone.2024.117373.

"Heat of the Moment: The Overlooked Key to Cartilage Engineering''

T. StampoultzisY. GuoD. P. Pioletti

ACS OMEGA. 2025. DOI : 10.1021/acsomega.4c10624.

2024

Banked Primary Progenitor Cells for Allogeneic Intervertebral Disc (IVD) Therapy: Preclinical Qualification and Functional Optimization within a Cell Spheroid Formulation Process

A. JeanneratC. PeneveyreS. JaccoudV. PhilippeC. Scaletta  et al.

Pharmaceutics. 2024. DOI : 10.3390/pharmaceutics16101274.

An Adhesive Hydrogel Technology for Enhanced Cartilage Repair: A Preliminary Proof of Concept

P. KaramiR. MartinA. LaurentH. Y. NamV. Philippe  et al.

Gels. 2024. DOI : 10.3390/gels10100657.

Development and Performance Evaluation of Hybrid Iono-organogels for Efficient Impact Mitigation

V. VarangesV. K. RanaV. PhillippeP.-E. BourbanD. Pioletti

ACS Applied Engineering Materials. 2024. DOI : 10.1021/acsaenm.4c00402.

Cartilage Repair: Promise of Adhesive Orthopedic Hydrogels

P. KaramiA. LaurentV. PhilippeL. A. ApplegateD. P. Pioletti  et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2024. DOI : 10.3390/ijms25189984.

Design of Customized Mouthguards with Superior Protection Using Digital-Based Technologies and Impact Tests

N. NasrollahzadehD. P. PiolettiM. Broome

Sports Medicine-Open. 2024. DOI : 10.1186/s40798-024-00728-2.

Glenohumeral joint force prediction with deep learning

P. EghbaliF. BecceP. GoettiP. BuchlerD. P. Pioletti  et al.

Journal Of Biomechanics. 2024. DOI : 10.1016/j.jbiomech.2024.111952.

Impact of Molecular Dynamics of Polyrotaxanes on Chondrocytes in Double-Network Supramolecular Hydrogels under Physiological Thermomechanical Stimulation

T. StampoultzisV. K. RanaY. GuoD. P. Pioletti

Biomacromolecules. 2024. DOI : 10.1021/acs.biomac.3c01132.

2023

Unraveling cartilage degeneration through synergistic effects of hydrostatic pressure and biomimetic temperature increase

Y. GuoT. StampoultzisN. NasrollahzadehP. KaramiV. K. Rana  et al.

Iscience. 2023. DOI : 10.1016/j.isci.2023.108519.

Enhancing Robustness of Adhesive Hydrogels through PEG-NHS Incorporation

E. UsluV. K. RanaY. GuoT. StampoultzisF. Gorostidi  et al.

ACS Applied Materials & Interfaces. 2023. DOI : 10.1021/acsami.3c13062.

Wet adhesive hydrogels to correct malacic trachea (tracheomalacia) A proof of concept

E. UsluV. K. RanaS. AnagnostopoulosP. KaramiA. Bergadano  et al.

Iscience. 2023. DOI : 10.1016/j.isci.2023.107168.

A guide to preclinical evaluation of hydrogel-based devices for treatment of cartilage lesions

P. KaramiT. StampoultzisY. GuoD. P. Pioletti

Acta Biomaterialia. 2023. DOI : 10.1016/j.actbio.2023.01.015.

Mimicking Loading-Induced Cartilage Self-Heating in Vitro Promotes Matrix Formation in Chondrocyte-Laden Constructs with Different Mechanical Properties

T. StampoultzisY. GuoN. NasrollahzadehP. KaramiD. P. Pioletti

Acs Biomaterials Science & Engineering. 2023. DOI : 10.1021/acsbiomaterials.2c00723.

2022

NIR Light-Mediated Photocuring of Adhesive Hydrogels for Noninvasive Tissue Repair via Upconversion Optogenesis

P. KaramiV. K. RanaQ. ZhangA. BonifaceY. Guo  et al.

Biomacromolecules. 2022. DOI : 10.1021/acs.biomac.2c00811.

Age- and sex-specific normative values of bone mineral density in the adult glenoid

P. EghbaliF. BecceP. GoettiF. VauclairA. Farron  et al.

Journal Of Orthopaedic Research. 2022. DOI : 10.1002/jor.25379.

Temperature evolution following joint loading promotes chondrogenesis by synergistic cues via calcium signaling

N. NasrollahzadehP. KaramiJ. WangL. BagheriY. Guo  et al.

Elife. 2022. DOI : 10.7554/eLife.72068.

2021

A Matlab toolbox for scaled-generic modeling of shoulder and elbow

E. SarshariY. BoulanaacheA. TerrierA. FarronP. Mullhaupt  et al.

Scientific Reports. 2021. DOI : 10.1038/s41598-021-99856-y.

Silk granular hydrogels self-reinforced with regenerated silk fibroin fibers

C. S. WyssP. KaramiA. DemongeotP.-E. BourbanD. Pioletti

Soft Matter. 2021. DOI : 10.1039/D1SM00585E.

Thoughts on cartilage tissue engineering: A 21st century perspective

T. StampoultzisP. KaramiD. P. Pioletti

Current Research in Translational Medicine. 2021. DOI : 10.1016/j.retram.2021.103299.

An Intrinsically-Adhesive Family of Injectable and Photo-Curable Hydrogels with Functional Physicochemical Performance for Regenerative Medicine

P. KaramiN. NasrollahzadehC. WyssA. O'SullivanM. Broome  et al.

Macromolecular Rapid Communications. 2021. DOI : 10.1002/marc.202000660.

An Off-the-Shelf Tissue Engineered Cartilage Composed of Optimally Sized Pellets of Cartilage Progenitor/Stem Cells

J. RanY. FeiC. WangD. RuanY. Hu  et al.

Acs Biomaterials Science & Engineering. 2021. DOI : 10.1021/acsbiomaterials.9b01863.

Development of Standardized Fetal Progenitor Cell Therapy for Cartilage Regenerative Medicine: Industrial Transposition and Preliminary Safety in Xenogeneic Transplantation

A. LaurentP. Abdel-SayedA. DucrotN. Hirt-BurriC. Scaletta  et al.

Biomolecules. 2021. DOI : 10.3390/biom11020250.

Pulsatile Flow-Induced Fatigue-Resistant Photopolymerizable Hydrogels for the Treatment of Intracranial Aneurysms

O. PoupartR. ContiA. SchmockerL. PancaldiC. Moser  et al.

Frontiers in Bioengineering and Biotechnology. 2021. DOI : 10.3389/fbioe.2020.619858.

Feasibility of an alternative method to estimate glenohumeral joint center from videogrammetry measurements and CT/MRI of patients

E. SarshariM. MancusoA. TerrierA. FarronP. Mullhaupt  et al.

Computer Methods In Biomechanics And Biomedical Engineering. 2021. DOI : 10.1080/10255842.2020.1808889.

Muscle co-contraction in an upper limb musculoskeletal model: EMG-assisted vs. standard load-sharing

E. SarshariM. MancusoA. TerrierA. FarronP. Mullhaupt  et al.

Computer Methods in Biomechanics and Biomedical Engineering. 2021. DOI : 10.1080/10255842.2020.1814755.

2020

Glenoid bone strain after anatomical total shoulder arthroplasty: In vitro measurements with micro-CT and digital volume correlation

Y. BoulanaacheF. BecceA. FarronD. PiolettiA. Terrier  et al.

Medical Engineering & Physics. 2020. DOI : 10.1016/j.medengphy.2020.09.009.

Hybrid granular hydrogels: combining composites and microgels for extended ranges of material properties

C. S. WyssP. KaramiP.-E. BourbanD. P. Pioletti

Soft Matter. 2020. DOI : 10.1039/d0sm00213e.

In vitro Implementation of Photopolymerizable Hydrogels as a Potential Treatment of Intracranial Aneurysms

O. PoupartA. SchmockerR. ContiC. MoserK. M. Nuss  et al.

Frontiers in Bioengineering and Biotechnology. 2020. DOI : 10.3389/fbioe.2020.00261.

Efficient decellularization of equine tendon with preserved biomechanical properties and cytocompatibility for human tendon surgery indications

P.-A. AeberhardA. GrognuzC. PeneveyreS. McCallinN. Hirt-Burri  et al.

Artificial Organs. 2020. DOI : 10.1111/aor.13581.

Light-Activated, Bioadhesive, Poly(2-hydroxyethyl methacrylate) Brush Coatings

J. WangP. KaramiN. C. AtamanD. P. PiolettiT. W. J. Steele  et al.

Biomacromolecules. 2020. DOI : 10.1021/acs.biomac.9b01196.

2019

Control of Dissipation Sources: A Central Aspect for Enhancing the Mechanical and Mechanobiological Performances of Hydrogels

N. NasrollahzadehP. KaramiD. P. Pioletti

ACS Applied Materials & Interfaces. 2019. DOI : 10.1021/acsami.9b15450.

Knitted Silk-Collagen Scaffold Incorporated with Ligament Stem/Progenitor Cells Sheet for Anterior Cruciate Ligament Reconstruction and Osteoarthritis Prevention

D. RuanT. ZhuJ. HuangH. LeY. Hu  et al.

ACS Biomaterials Science & Engineering. 2019. DOI : 10.1021/acsbiomaterials.9b01041.

Patellar bone strain after total knee arthroplasty is correlated with bone mineral density and body mass index

A. LatypovaE. TaghizadehF. BecceP. BüchlerB. M. Jolles  et al.

Medical Engineering & Physics. 2019. DOI : 10.1016/j.medengphy.2019.03.017.

2018

Decellularised tissues obtained by a CO2-philic detergent and supercritical CO2

J. AntonsM. MarascioP. AeberhardG. WeissenbergerN. Hirt-Burri  et al.

European Cells and Materials. 2018. DOI : 10.22203/eCM.v036a07.

Non-setting, injectable biomaterials containing particulate hydroxyapatite can increase primary stability of bone screws in cancellous bone

J. Solana MuñozU. KettenbergerP. ProcterD. P. Pioletti

Clinical Biomechanics. 2018. DOI : 10.1016/j.clinbiomech.2018.09.023.

Depth-dependent mechanical properties of human articular cartilage obtained by indentation measurements

J. AntonsM. G. M. MarascioJ. Nohavar. MartinL. A. Laurent-Applegate  et al.

Journal of Materials Science: Materials in Medicine. 2018. DOI : 10.1007/s10856-018-6066-0.

Effect of a collar on subsidence and local micromotion of cementless femoral stems: in vitro comparative study based on micro-computerised tomography

V. M. CamineH. A. RuedigerD. P. PiolettiA. Terrier

International Orthopaedics. 2018. DOI : 10.1007/s00264-017-3524-0.

Fatigue as the missing link between bone fragility and fracture

C. AcevedoV. A. StadelmannD. PiolettiT. AllistonR. O. Ritchie

Nature Biomedical Engineering. 2018. DOI : 10.1038/s41551-017-0183-9.

Composite Double-Network Hydrogels To Improve Adhesion on Biological Surfaces

P. KaramiC. S. WyssA. KhoushabiA. SchmockerM. Broome  et al.

ACS Applied Materials & Interfaces. 2018. DOI : 10.1021/acsami.8b10735.

Cyclic loading of a cellulose/hydrogel composite increases its fracture strength

C. S. WyssP. KaramiP.-E. BourbanD. P. Pioletti

Extreme Mechanics Letters. 2018. DOI : 10.1016/j.eml.2018.09.002.

2017

Micromotion-induced peri-prosthetic fluid flow around a cementless femoral stem

V. Malfroy CamineA. TerrierD. Pioletti

Computer Methods in Biomechanics and Biomedical Engineering. 2017. DOI : 10.1080/10255842.2017.1296954.

Human bone progenitor cells for clinical application: what kind of immune reaction does fetal xenograft tissue trigger in immuno-competent rats?

T. C. HausherrK. NussE. TheinL. A. Laurent-ApplegateD. Pioletti

Cell Transplantation. 2017. DOI : 10.3727/096368916X693789.

In vitro and in vivo investigation of bisphosphonate-loaded hydroxyapatite particles for peri-implant bone augmentation

U. KettenbergerV. LuginbuehlP. ProcterD. Pioletti

Journal of Tissue Engineering and Regenerative Medicine. 2017. DOI : 10.1002/term.2094.

3D Printing of Polymers with Hierarchical Continuous Porosity

M. G. M. MarascioJ. AntonsD. P. PiolettiP.-E. Bourban

Advanced Materials Technologies. 2017. DOI : 10.1002/admt.201700145.

Effects of glenoid inclination and acromion index on humeral head translation and glenoid articular cartilage strain

C. EngelhardtA. FarronF. BecceN. PlaceD. P. Pioletti  et al.

Journal of Shoulder and Elbow Surgery. 2017. DOI : 10.1016/j.jse.2016.05.031.

Ectopic tissue engineered ligament with silk collagen scaffold for ACL regeneration: A preliminary study

J. RanY. HuH. LeY. ChenZ. Zheng  et al.

Acta Biomaterialia. 2017. DOI : 10.1016/j.actbio.2017.02.027.

Importance of trabecular anisotropy in finite element predictions of patellar strain after Total Knee Arthroplasty

A. LatypovaD. PiolettiA. Terrier

Medical Engineering & Physics. 2017. DOI : 10.1016/j.medengphy.2016.10.003.

Development of an effective cell seeding technique: simulation, implementation and analysis of contributing factors

N. Nasrollahzadeh MamaghaniL. ApplegateD. Pioletti

Tissue Engineering C. 2017. DOI : 10.1089/ten.tec.2017.0108.

Alignment of collagen fiber in knitted silk scaffold for functional massive rotator cuff repair

Z. ZhengJ. RanW. ChenY. HuT. Zhu  et al.

Acta Biomaterialia. 2017. DOI : 10.1016/j.actbio.2017.01.041.

A simulation framework for humeral head translations

E. SarshariA. FarronA. TerrierD. PiolettiP. Müllhaupt

Medical Engineering and Physics. 2017. DOI : 10.1016/j.medengphy.2017.08.013.

2016

Anti-microbial dendrimers against multidrug-resistant P. aeruginosa enhance the angiogenic effect of biological burn-wound bandages

P. Abdel-SayedA. KaeppliT. SiriwardenaT. DarbreK. Perron  et al.

Scientific Reports. 2016. DOI : 10.1038/srep22020.

Biodegradable HEMA-based hydrogels with enhanced mechanical properties

M. N. MoghadamD. Pioletti

Journal of Biomedical Materials Research Part B. 2016. DOI : 10.1002/jbm.b.33469.

Stability enhancement using hyaluronic acid gels for delivery of human fetal progenitor tenocytes

A. GrognuzC. ScalettaA. FarronD. PiolettiW. Raffoul  et al.

Cell Medicine. 2016. DOI : 10.3727/215517916X690486.

A patient-specific model of total knee arthroplasty to estimate patellar strain: A case study

A. LatypovaA. AramiF. BecceB. Jolles-HaeberliK. Aminian  et al.

Clinical Biomechanics. 2016. DOI : 10.1016/j.clinbiomech.2015.11.008.

Identification of elastic properties of human patellae using micro-finite element analysis

A. LatypovaG. MaquerK. ElankumaranD. PahrP. Zysset  et al.

Journal of Biomechanics. 2016. DOI : 10.1016/j.jbiomech.2016.07.031.

Experimental method to characterize the strain dependent permeability of tissue engineering scaffolds

N. Nasrollahzadeh MamaghaniD. Pioletti

Journal of Biomechanics. 2016. DOI : 10.1016/j.jbiomech.2016.09.021.

Osteogenesis imperfecta: from diagnosis and multidisciplinary treatment to future perspectives

A. Bregou BourgeoisB. Aubry-RozierL. BonaféL. A. Laurent-ApplegateD. Pioletti  et al.

Swiss Medical Weekly. 2016. DOI : 10.4414/smw.2016.14322.

A photopolymerized composite hydrogel and surgical implanting tool for a nucleus pulposus replacement

A. SchmockerA. KhoushabiD. A. FrauchigerB. GantenbeinC. Schizas  et al.

Biomaterials. 2016. DOI : 10.1016/j.biomaterials.2016.02.015.

Full-field measurement of micromotion around a cementless femoral stem using micro-CT imaging and radiopaque markers

V. Malfroy CamineH. RüdigerD. PiolettiA. Terrier

Journal of Biomechanics. 2016. DOI : 10.1016/j.jbiomech.2016.10.029.

2015

Novel micropatterns mechanically control fibrotic reactions at the surface of silicone implants

H. MajdS. SchererS. BooS. RamondettiE. Cambridge  et al.

Biomaterials. 2015. DOI : 10.1016/j.biomaterials.2015.03.027.

Improving hydrogels’ toughness by increasing the dissipative properties of their network

M. Nassajian MoghadamD. Pioletti

Journal of the Mechanical Behavior of Biomedical Materials. 2015. DOI : 10.1016/j.jmbbm.2014.10.010.

Time course of bone screw fixation following a local delivery of zoledronate in a rat femoral model – a micro-finite element analysis

U. KettenbergerA. LatypovaA. TerrierD. Pioletti

Journal of the Mechanical Behavior of Biomedical Materials. 2015. DOI : 10.1016/j.jmbbm.2015.01.007.

Photo-polymerization, swelling and mechanical properties of cellulose fibre reinforced poly(ethylene glycol) hydrogels

A. KhoushabiA. SchmockerD. PiolettiC. MoserC. Schizas  et al.

Composites Science and Technology. 2015. DOI : 10.1016/j.compscitech.2015.10.002.

Variability of the pullout strength of cancellous bone screws with cement augmentation

P. ProcterP. BennaniC. BrownJ. ArnoldiD. Pioletti  et al.

Clinical Biomechanics -Bristol-. 2015. DOI : 10.1016/j.clinbiomech.2015.03.003.

Comparison of an EMG-based and a stress-based method to predict shoulder muscle forces

C. EngelhardtV. M. CamineD. IngramP. MuellhauptA. Farron  et al.

Computer Methods In Biomechanics And Biomedical Engineering. 2015. DOI : 10.1080/10255842.2014.899587.

Effect of partial-thickness tear on loading capacities of the supraspinatus tendon: a finite element analysis

C. EngelhardtD. IngramP. MüllhauptA. FarronF. Becce  et al.

Computer Methods in Biomechanics and Biomedical Engineering. 2015. DOI : 10.1080/10255842.2015.1075012.

Impact of synovial fluid flow on temperature regulation in knee cartilage

M. Nassajian MoghadamP. Abdel-SayedV. Malfroy CamineD. Pioletti

Journal of Biomechanics. 2015. DOI : 10.1016/j.jbiomech.2014.11.008.

Strategies for improving the repair of focal cartilage defects

P. Abdel-SayedD. P. Pioletti

Nanomedicine. 2015. DOI : 10.2217/nnm.15.119.

Miniature probe for the delivery and monitoring of a photopolymerizable material

A. SchmockerA. KhoushabiC. SchizasP.-E. BourbanD. Pioletti  et al.

Journal of Biomedical Optics (JBO). 2015. DOI : 10.1117/1.Jbo.20.12.127001.

Mechanical evaluation of a tissue-engineered zone of calcification in a bone-hydrogel osteochondral construct

J. HollensteinA. TerrierE. CoryA. C. ChenR. L. Sah  et al.

Computer Methods in Biomechanics and Biomedical Engineering. 2015. DOI : 10.1080/10255842.2013.794898.

2014

Energy dissipation as a mechanobiological variable inducing chondrogenesis

P. Abdel-SayedS. DarwicheU. KettenbergerD. Pioletti

Journal Of Tissue Engineering And Regenerative Medicine. 2014.

The role of energy dissipation of polymeric scaffolds in the mechanobiological modulation of chondrogenic expression

P. Abdel-SayedS. E. DarwicheU. KettenbergerD. Pioletti

Biomaterials. 2014. DOI : 10.1016/j.biomaterials.2013.11.048.

Does locally delivered Zoledronate influence peri-implant bone formation? – Spatio-temporal monitoring of bone remodeling in vivo

U. KettenbergerJ. StonE. TheinP. ProcterD. Pioletti

Biomaterials. 2014. DOI : 10.1016/j.biomaterials.2014.09.005.

Controlled release from a mechanically-stimulated thermosensitive self-heating composite hydrogel

M. Nassajian MoghadamV. KolesovH.-A. KlokD. Pioletti

Biomaterials. 2014. DOI : 10.1016/j.biomaterials.2013.09.065.

Photopolymerizable hydrogels for implants: Monte-Carlo modeling and experimental in vitro validation

A. SchmockerA. KhoushabiC. SchizasP.-E. BourbanD. Pioletti  et al.

Journal of Biomedical Optics (JBO). 2014. DOI : 10.1117/1.Jbo.19.3.035004.

Intrinsic viscoelasticity increases temperature in knee cartilage under physiological loading

P. Abdel-SayedM. Nassajian MoghadamR. SalomirD. TcherninD. Pioletti

Journal of the Mechanical Behavior of Biomedical Materials. 2014. DOI : 10.1016/j.jmbbm.2013.10.025.

Translation of biomechanical concepts in bone tissue engineering: from animal study to revision knee arthroplasty

A. Roshan GhiasA. TerrierB. Jolles-HaeberliD. Pioletti

Computer Methods in Biomechanics and Biomedical Engineering. 2014. DOI : 10.1080/10255842.2012.719607.

2013

Capillary-valve-based platform towards cell-on-chip mechanotransduction assays

T. C. HausherrH. MajdD. JossA. MüllerD. Pioletti  et al.

Sensors and Actuators B. 2013. DOI : 10.1016/j.snb.2013.07.050.

Cartilage self-heating contributes to chondrogenic expression

P. Abdel-SayedA. VogelM. Nassajian MoghadamD. Pioletti

European Cells and Materials. 2013. DOI : 10.22203/eCM.v026a12.

Effect of a pathological scapular tilt after total shoulder arthroplasty

M. RöthlisbergerD. PiolettiA. FarronA. Terrier

Computer Methods in Biomechanics and Biomedical Engineering. 2013. DOI : 10.1080/10255842.2012.656612.

A flow sensing model for mesenchymal stromal cells using morphogen dynamics

M. GortchacowA. TerrierD. Pioletti

Biophysical Journal. 2013. DOI : 10.1016/j.bpj.2013.04.014.

Integration of mechanotransduction concepts in bone tissue engineering

D. Pioletti

Computer Methods in Biomechanics and Biomedical Engineering. 2013. DOI : 10.1080/10255842.2013.780602.

Activities of daily living with reverse prostheses: importance of scapular compensation for functional mobility of the shoulder

A. TerrierP. ScheuberD. P. PiolettiA. Farron

Journal Of Shoulder And Elbow Surgery. 2013. DOI : 10.1016/j.jse.2012.09.014.

Importance of the subscapularis muscle after total shoulder arthroplasty

A. TerrierX. LarreaV. Malfroy CamineD. PiolettiA. Farron

Clinical Biomechanics. 2013. DOI : 10.1016/j.clinbiomech.2012.11.010.

Response to Letter to the Editor: Comment on "injectable calcium phosphate cement for augmentation around cancellous bone screws. In vivo biomechanical studies"

D. P. Pioletti

Journal Of Biomechanics. 2013. DOI : 10.1016/j.jbiomech.2012.09.024.

2012

Synthesis and photopolymerization of Tween 20 Methacrylate/N-vinyl-2-Pyrrolidone blend

A. BorgesC. JayakrishnanP.-E. BourbanJ. C. PlummerD. Pioletti  et al.

Materials Science and Engineering C. 2012. DOI : 10.1016/j.msec.2012.06.009.

Damping properties of the nucleus pulposus

A. VogelD. Pioletti

Clinical Biomechanics -Bristol-. 2012. DOI : 10.1016/j.clinbiomech.2012.06.005.

Epiphyseal chondro-progenitors provide a stable cell source for cartilage cell therapy

S. E. DarwicheC. ScalettaW. RaffoulD. PiolettiL. Applegate

Cell Medicine. 2012. DOI : 10.3727/215517912X639324.

Injectable calcium phosphate cement for augmentation around cancellous bone screws. In vivo biomechanical studies

S. LarssonV. StadelmannJ. ArnoldiM. BehrensB. Hess  et al.

Journal of Biomechanics. 2012. DOI : 10.1016/j.jbiomech.2012.02.004.

Importance of polyethylene thickness in total shoulder arthroplasty: A finite element analysis

A. TerrierV. BrighentiD. P. PiolettiA. Farron

Clinical Biomechanics. 2012. DOI : 10.1016/j.clinbiomech.2011.12.003.

Simultaneous and multisite measure of micromotion, subsidence and gap to evaluate femoral stem stability

M. GortchacowM. WettsteinD. PiolettiM. Müller-GerblA. Terrier

Journal of Biomechanics. 2012. DOI : 10.1016/j.jbiomech.2012.01.040.

2011

Biomechanics and tissue engineering

D. P. Pioletti

Osteoporosis International. 2011. DOI : 10.1007/s00198-011-1616-z.

Human fetal bone cells in delivery systems for bone engineering

T. HolandaD. MariaC. ScalettaS. JaccoudN. Hirt-Burri  et al.

Journal of Tissue Engineering and Regenerative Medicine. 2011. DOI : 10.1002/term.381.

A new technique to measure micromotion distribution around a cementless femoral stem

M. GortchacowM. WettsteinD. P. PiolettiA. Terrier

Journal of Biomechanics. 2011. DOI : 10.1016/j.jbiomech.2010.09.023.

Regulation of proliferation and differentiation of human fetal bone cells

N. KrattingerL. A. ApplegateE. BivierD. P. PiolettiJ. Caverzasio

European Cells and Materials. 2011. DOI : 10.22203/eCM.v021a04.

Nanofibrillated cellulose composite hydrogel for the replacement of the nucleus pulposus

A. C. BorgesC. EyholzerF. DucP.-E. BourbanP. Tingaut  et al.

Acta biomaterialia. 2011. DOI : 10.1016/j.actbio.2011.05.029.

Prediction of spatio-temporal bone formation in scaffold by diffusion equation

A. Roshan GhiasA. VogelL. RakotomananaD. P. Pioletti

Biomaterials. 2011. DOI : 10.1016/j.biomaterials.2011.05.085.

Surgical preparation of bone-scaffold interface is critical for bone regeneration inside tissue engineering scaffold

A. Roshan-GhiasD. P. Pioletti

Journal of Orthopaedic Research. 2011. DOI : 10.1002/jor.21290.

In vivo loading increases mechanical properties of scaffold by affecting bone formation and bone resorption rates

A. Roshan GhiasF. LambersM. Gholam-RezaeeR. MüllerD. Pioletti

Bone. 2011. DOI : 10.1016/j.bone.2011.09.040.

In vivo assessment of local effects after application of bone screws delivering bisphosphonates into a compromised cancellous bone site

A. Roshan GhiasJ. ArnoldiP. ProcterD. P. Pioletti

Clinical Biomechanics -Bristol-. 2011. DOI : 10.1016/j.clinbiomech.2011.06.004.

Biologicals and fetal cell therapy for wound healing and scar management

N. Hirt-BurriA.-A. RameletW. RaffoulA. De Buys RoessinghC. Scaletta  et al.

ISRN Dermatology. 2011. DOI : 10.5402/2011/549870.

Combined effects of zoledronate and mechanical stimulation on bone adaptation in an axially loaded mouse tibia

V. A. StadelmannN. BonnetD. P. Pioletti

Clinical Biomechanics. 2011. DOI : 10.1016/j.clinbiomech.2010.08.014.

Bone regeneration and stem cells

K. ArvidsonB. M. AbdallahL. A. ApplegateN. BaldiniE. Cenni  et al.

Journal of Cellular and Molecular Medicine. 2011. DOI : 10.1111/j.1582-4934.2010.01224.x.

2010

A musculoskeletal shoulder model based on pseudo-inverse and null-space optimization

A. TerrierM. AeberhardY. MichellodP. MüllhauptD. Gillet  et al.

Medical Engineering and Physics. 2010. DOI : 10.1016/j.medengphy.2010.07.006.

Curing Kinetics and Mechanical Properties of a Composite Hydrogel for the Replacement of the Nucleus Pulposus

A. BorgesP.-E. BourbanD. P. PiolettiJ.-A. E. Månson

Composites Science and Technology. 2010. DOI : 10.1016/j.compscitech.2010.07.018.

Plasticity of fetal cartilaginous cells

A. QuintinC. SchizasC. ScalettaS. JaccoudL. A. Applegate  et al.

Cell Transplantation. 2010. DOI : 10.3727/096368910X506854.

Augmentation of bone defect healing using a new biocomposite scaffold: an in vivo study in sheep

U. van der PolL. MathieuS. ZeiterP.-E. BourbanP.-Y. Zambelli  et al.

Acta Biomaterialia. 2010. DOI : 10.1016/j.actbio.2010.03.028.

Tightening force and torque of nonlocking screws in a reverse shoulder prosthesis

A. TerrierS. KochbeckF. MerliniM. GortchacowD. P. Pioletti  et al.

Clinical Biomechanics -Bristol-. 2010. DOI : 10.1016/j.clinbiomech.2010.03.011.

Biomechanics in bone tissue engineering

D. P. Pioletti

Computer Methods In Biomechanics And Biomedical Engineering. 2010. DOI : 10.1080/10255841003630660.

The skeletal key

D. Pioletti

Public Service Review: Science and Technology. 2010.

Calcium phosphate augmentation of cancellous bone screws in impaired lapine bone (vol 40, pg S23, 2009)

V. A. StadelmannP. ProcterJ. ArnoldiM. MurphyB. Hess  et al.

Injury-International Journal Of The Care Of The Injured. 2010. DOI : 10.1016/j.injury.2009.09.026.

From bench to bedside

L. A. ApplegateD. Pioletti

EPC Drug Discovery, Delivery & Therapeutics. 2010.

Biomechanical consequences of humeral component malpositioning after anatomical total shoulder arthroplasty

A. TerrierS. RamondettiF. MerliniD. P. PiolettiA. Farron

Journal of Shoulder and Elbow Surgery. 2010. DOI : 10.1016/j.jse.2010.06.006.

In vivo cyclic loading as a potent stimulatory signal for bone formation inside tissue engineering scaffolds

A. Roshan GhiasA. TerrierP.-E. BourbanD. Pioletti

European Cells and Materials. 2010. DOI : 10.22203/ecm.v019a05.

Mechanical interaction between cells and fluid for bone tissue engineering scaffold: modulation of the interfacial shear stress

L. D. BlechaL. RakotomananaF. RazafimaheriA. TerrierD. P. Pioletti

Journal of Biomechanicsanics. 2010. DOI : 10.1016/j.jbiomech.2009.11.004.

Calcium phosphate cement augmentation of cancellous bone screws can compensate for the absence of cortical fixation

V. StadelmannE. BrettonA. TerrierP. ProcterD. P. Pioletti

Journal of Biomechanics. 2010. DOI : 10.1016/j.jbiomech.2010.07.025.

2009

Isolation and in vitro chondrogenic potential of human fetal spine cells

A. QuintinC. SchizasC. ScalettaS. JaccoudS. Gerber  et al.

Journal of Cellular and Molecular Medicine. 2009. DOI : 10.1111/j.1582-4934.2008.00630.x.

Total shoulder arthroplasty: Downward inclination of the glenoid component to balance supraspinatus deficiency

A. TerrierF. MerliniD. P. PiolettiA. Farron

Journal of Shoulder and Elbow Surgery. 2009. DOI : 10.1016/j.jse.2008.11.008.

Chronic wound healing by fetal cell therapy may be explained by differential gene profiling observed in fetal versus old skin cells

A. A. RameletN. Hirt-BurriW. RaffoulC. ScalettaD. P. Pioletti  et al.

Exp Gerontology. 2009. DOI : 10.1016/j.exger.2008.11.004.

In vitro characterization of immune-related properties of human fetal bone cells for potential tissue engineering applications

M.-O. MontjoventC. Bocelli-TyndallC. ScalettaA. ScherberichS. Mark  et al.

Tissue Engineering. 2009. DOI : 10.1089/ten.tea.2008.0222.

Whole-cell bioprocessing of human fetal cells for tissue engineering of skin

L. A. ApplegateC. ScalettaN. Hirt-BurriW. RaffoulD. P. Pioletti

Skin Pharmacol Physio. 2009. DOI : 10.1159/000178865.

Prediction of bone density around orthopedic implants delivering bisphosphonate

V. A. StadelmannA. TerrierO. GauthierJ.-M. BoulerD. P. Pioletti

Journal of Biomechanicsanics. 2009. DOI : 10.1016/j.jbiomech.2009.03.024.

3D strain map of axially loaded mouse tibia: a numerical analysis validated by experimental measurements

V. A. StadelmannJ. HockeJ. VerhelleV. ForsterF. Merlini  et al.

Computer Methods In Biomechanics And Biomedical Engineering. 2009. DOI : 10.1080/10255840802178053.

Biomechanical evaluation of porous biodegradable scaffolds for revision knee arthroplasty

A. TerrierM. Sedighi-GilaniA. Roshan GhiasL. AschwandenD. P. Pioletti

Computer Methods in Biomechanics and Biomedical Engineering. 2009. DOI : 10.1080/10255840802603589.

Comparison of polyethylene wear in anatomical and reversed shoulder prostheses

A. TerrierF. MerliniD. P. PiolettiA. Farron

Journal of Bone and Joint Surgery [Br]. 2009. DOI : 10.1302/0301-620X.91B7.21999.

Osteoclastogenesis can be mechanically-induced in the peri-implant bone

V. StadelmannA. TerrierD. P. Pioletti

Biomedical Engineering and Research. 2009. DOI : 10.1016/j.irbm.2008.10.003.

Targeted mechanical properties for optimal fluid motion inside artificial bone substitutes

L. D. BlechaL. RakotomananaF. RazafimaheryA. TerrierD. P. Pioletti

Journal of Orthopedic Research. 2009. DOI : 10.1002/jor.20836.

3D strain map of axially loaded mouse tibia: a numerical analysis validated by experimental measurements

V. A. StadelmannJ. HockéV. JensenV. ForsterF. Merlini  et al.

Comput Methods Biomech Biomed Engin. 2009. DOI : 10.1080/10255840903094035.

2008

Orthopedic implant used as drug delivery system: clinical situation and state of the research

D. P. PiolettiO. GauthierV. A. StadelmannB. BujoliJ. Guicheux  et al.

Current Drug Delivery. 2008.

Human muscular fetal cells: a potential cell source for muscular therapies

N. Hirt-BurriA. S. de Buys RoessinghC. ScalettaS. GerberD. P. Pioletti  et al.

Pediatr Surg Int. 2008. DOI : 10.1007/s00383-007-2040-5.

Wound healing gene-family expression differences between fetal and foreskin cells used for bioengineered skin substitutes

N. Hirt-BurriC. ScalettaS. GerberD. P. PiolettiL. A. Applegate

Artificial Organs. 2008. DOI : 10.1111/j.1525-1594.2008.00578.x.

Human fetal bone cells associated with ceramic reinforced PLA scaffolds for tissue engineering

M.-O. MontjoventS. MarkL. MathieuC. ScalettaA. Scherberich  et al.

Bone. 2008. DOI : 10.1016/j.bone.2007.10.018.

Implants delivering bisphosphonate locally increase periprosthetic bone density in an osteoporotic sheep model. A pilot study

V. A. StadelmannA. TerrierO. GauthierJ.-M. BoulerD. P. Pioletti

European Cells and Materials. 2008. DOI : 10.22203/ecm.v016a02.

Microstimulations at the bone implant interface upregulate osteoclast activation pathway

V. A. StadelmannA. TerrierD. P. Pioletti

Bone. 2008. DOI : 10.1016/j.bone.2007.09.055.

2007

Repair of critical size defects in the rat cranium using ceramic-reinforced PLA scaffolds obtained by supercritical gas foaming

M. O. MontjoventL. MathieuH. SchmoekelS. MarkP.-E. Bourban  et al.

Journal of Biomedical Materials Research Part A. 2007. DOI : 10.1002/jbm.a.31208.

Biomechanical evaluation of intra-articular and extra-articular procedures in anterior cruciate ligament reconstruction: A finite element analysis

N. RamanirakaP. SaunierO. SiegristD. P. Pioletti

Clinical Biomechanics. 2007. DOI : 10.1016/j.clinbiomech.2006.10.006.

Polylactic acid-phosphate glass composite foams as scaffolds for tissue engineering

G. GeorgiouL. MathieuD. P. PiolettiP.-E. BourbanJ.-A. Månson  et al.

J Biomed Mater Res B. 2007. DOI : 10.1002/jbmb.

Consistency of fetal cell banks for research and clinical use

A. QuintinN. Hirt-BuriC. ScalettaC. SchizasD. P. Pioletti  et al.

Cell Transplantation. 2007. DOI : 10.3727/000000007783465127.

2006

Local delivery of bisphosphonate from coated orthopedic implants increases implants mechanical stability in osteoporotic rats

B. PeterO. GauthierS. LaibB. BujoliJ. Guicheux  et al.

Journal of Biomedical Materials Research Part A. 2006. DOI : 10.1002/jbm.a.30456.

Architecture and properties of anisotropic polymer composite scaffolds for bone tissue engineering

L. M. MathieuT. L. MuellerP.-E. BourbanD. P. PiolettiR. Müller  et al.

Biomaterials. 2006. DOI : 10.1016/j.biomaterials.2005.07.015.

Total joint replacement and aseptic loosening

Y. KonttinenT. WrightR. TrebseM. TakagiM. Silbermann  et al.

Helix Review Series Rheumatology. 2006.

Bone tissue engineering using fetal cell therapy

D. P. PiolettiM. MontjoventP. ZambelliL. Applegate

Swiss Medical Weekly. 2006. DOI : 10.4414/smw.2006.11411.

2005

Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration

B. PeterD. P. PiolettiS. LaibB. BujoliP. Pilet  et al.

Bone. 2005. DOI : 10.1016/j.bone.2004.10.004.

The effect of bisphosphonates and titanium particles on osteoblasts: an in vitro study

B. PeterP. Y. ZambelliJ. GuicheuxD. P. Pioletti

Journal of Bone and Joint Surgery. 2005. DOI : 10.1302/0301-620X.87B8.15446.

How plate positioning impacts the biomechanics of the open wedge tibial osteotomy; a finite element analysis

L. D. BlechaP. Y. ZambelliN. A. RamanirakaP. E. BourbanJ. A. Manson  et al.

Comput Methods Biomech Biomed Engin. 2005. DOI : 10.1080/10255840500322433.

Bioresorbable composites prepared by supercritical fluid foaming

L. M. MathieuM. O. MontjoventP.-E. BourbanD. P. PiolettiJ.-A. E. Månson

Journal of Biomedical Materials Research Part A. 2005. DOI : 10.1002/jbm.a.30385.

Biocompatibility of bioresorbable poly(L-lactic acid) composite scaffolds obtained by supercritical gas foaming with human fetal bone cells

M.-O. MontjoventL. MathieuB. HinzL. L. ApplegateP.-E. Bourban  et al.

Tissue Engineering. 2005. DOI : 10.1089/ten.2005.11.1640.

2004

The influence of wear particles in the expression of osteoclastogenesis factors by osteoblasts

D. P. PiolettiA. Kottelat

Biomaterials. 2004. DOI : 10.1016/j.biomaterials.2004.01.053.

Fetal bone cells for tissue engineering

M. O. MontjoventN. BurriS. MarkE. FedericiC. Scaletta  et al.

Bone. 2004. DOI : 10.1016/j.bone.2004.07.001.

Can the increase of bone mineral density following bisphosphonates treatments be explained by biomechanical considerations?

D. P. PiolettiL. R. Rakotomanana

Clinical Biomechanics. 2004. DOI : 10.1016/j.clinbiomech.2003.10.002.

Peri-implant bone remodeling after total hip replacement combined with systemic alendronate treatment: a finite element analysis

B. PeterN. RamanirakaL. R. RakotomananaP. Y. ZambelliD. P. Pioletti

Comput Methods Biomech Biomed Engin. 2004. DOI : 10.1080/1025584042000205327.

2003

Effect of micromechanical stimulations on osteoblasts: development of a device simulating the mechanical situation at the bone-implant interface

D. P. PiolettiJ. MullerL. R. RakotomananaJ. CorbeilE. Wild

Journal of Biomechanics. 2003. DOI : 10.1016/S0021-9290(02)00301-9.

Biphasic constitutive laws for biological interface evolution

P. BuchlerD. P. PiolettiL. R. Rakotomanana

Biomech Model Mechanobiol. 2003. DOI : 10.1007/s10237-002-0024-x.

2002

Gene expression analysis of osteoblastic cells contacted by orthopedic implant particles

D. P. PiolettiL. LeoniD. GeniniH. TakeiP. Du  et al.

J Biomed Mater Res. 2002. DOI : 10.1002/jbm.10218.

Large-scale gene expression analysis of osteoblasts cultured on three different Ti-6Al-4V surface treatments

C. H. KuM. BrowneP. J. GregsonJ. CorbeilD. P. Pioletti

Biomaterials. 2002. DOI : 10.1016/S0142-9612(02)00161-8.

Effect of different Ti-6Al-4V surface treatments on osteoblasts behaviour

C. H. KuD. P. PiolettiM. BrowneP. J. Gregson

Biomaterials. 2002. DOI : 10.1016/S0142-9612(01)00266-6.

2001

Orthopedic implant used as a drug delivery system: a numerical study

B. PeterD. P. PiolettiA. TerrierL. Rakotomanana

Computer Methods in Biomechanics and Biomedical Engineering. 2001. DOI : 10.1080/10255840108908023.

2000

On the independence of time and strain effects in the stress relaxation of ligaments and tendons

D. P. PiolettiL. R. Rakotomanana

Journal of Biomechanics. 2000. DOI : 10.1016/S0021-9290(00)00128-7.

The effects of calcium phosphate cement particles on osteoblast functions

D. P. PiolettiH. TakeiT. LinP. Van LanduytQ. J. Ma  et al.

Biomaterials. 2000. DOI : 10.1016/S0142-9612(99)00250-1.

Combined effect of titanium particles and TNF-alpha on the production of IL-6 by osteoblast-like cells

H. TakeiD. P. PiolettiS. Y. KwonK. L. Sung

Journal of Biomedical Materials Research. 2000. DOI : 10.1002/1097-4636(200011)52:2<382::AID-JBM19>3.0.CO;2-V.

Non-linear viscoelastic laws for soft biological tissues

D. P. PiolettiL. R. Rakotomanana

European Journal of Mechanics a-Solids. 2000. DOI : 10.1016/S0997-7538(00)00202-3.

Titanium particles inhibit osteoblast adhesion to fibronectin-coated substrates

S. Y. KwonH. TakeiD. P. PiolettiT. LinQ. J. Ma  et al.

J Orthopaed Res. 2000. DOI : 10.1002/jor.1100180207.

1999

Strain rate effect on the mechanical behavior of the anterior cruciate ligament-bone complex

D. P. PiolettiL. R. RakotomananaP. F. Leyvraz

Medical Engineering & Physics. 1999. DOI : 10.1016/S1350-4533(99)00028-4.

The cytotoxic effect of titanium particles phagocytosed by osteoblasts

D. P. PiolettiH. TakeiS. Y. KwonD. WoodK. L. Sung

J Biomed Mater Res. 1999. DOI : 10.1002/(SICI)1097-4636(19990905)46:3<399::AID-JBM13>3.0.CO;2-B.

1998

Intrinsic coordinate system for the tibial plateau

D. P. PiolettiL. R. RakotomananaP. DahlgrenJ. VallottonP. F. Leyvraz

Knee. 1998. DOI : 10.1016/S0968-0160(97)10008-4.

Viscoelastic constitutive law in large deformations: application to human knee ligaments and tendons

D. P. PiolettiL. R. RakotomananaJ. F. BenvenutiP. F. Leyvraz

Journal of Biomechanics. 1998. DOI : 10.1016/S0021-9290(98)00077-3.

1997

Tibial component positioning in total knee arthroplasty: bone coverage and extensor apparatus alignment

P. LemaireD. P. PiolettiF. M. MeyerR. MeuliJ. Dorfl  et al.

knee surgery sports traumatology arthroscopy. 1997. DOI : 10.1007/s001670050059.

Displacements of the tibial tuberosity - Effects of the surgical parameters

J. F. BenvenutiL. RakotomananaP. F. LeyvrazD. P. PiolettiJ. H. Heegaard  et al.

Clinical Orthopaedics and Related Research. 1997.

1995

Experimental and mathematical methods for representing relative surface elongation of the ACL

D. P. PiolettiJ. H. HeegaardR. L. RakotomananaP. F. LeyvrazL. Blankevoort

Journal of Biomechanics. 1995. DOI : 10.1016/0021-9290(94)00160-6.

1994

Cinématique et élongation contiue du ligament croisé antérieur [Kinematics and continuous elongation of the anterior cruciate ligament]

D. P. PiolettiJ. H. HeegaardL. R. RakotomananaP. F. Leyvraz

Revue médicale de la Suisse romande. 1994.

Enseignement et PhD

Current Phd

Mi-Lane Bouchez, Deniz Cemre Turgut, Léa Pistorius, Sruthi Raja, Ramin Mohammadi, Antoine Reitzel, Alexander Arthur Nottegar

Past Phd As Director

Bastian Peter, Marc-Olivier Montjovent, Luc Blecha, Vincent Stadelmann, Aurélie Quintin, Arne Christian Vogel, Miguel Gortchacow, Alireza Roshan Ghias, Philippe Abdel Sayed, Jérôme Hollenstein, Salim Elias Darwiche, Ulrike Kettenberger, Mohamadreza Nassajian Moghadam, Adeliya Latypova, Christoph Anselm Engelhardt, Tanja Cloé Hausherr, Valérie Malfroy Camine, Matteo Gregorio Modesto Marascio, Ehsan Sarshari, Naser Nasrollahzadeh Mamaghani, Jens Antons, Céline Samira Wyss, Yasmine Boulanaache, Peyman Karami, Oriane Poupart, Theofanis Stampoultzis, Yanheng Guo, Ece Mailand, Pezhman Eghbalishamsabadi, Vincent Varanges

Past Phd As Codirector

Andreas Schmocker

Courses

B1.4 Système locomoteur - Anatomie du système locomoteur - Biomécanique (pour MED)

UNIL-125

NA

Biomechanics of the musculoskeletal system

ME-482

Les bases pour une description mécanique du système musculosquelettique sont présentées. Cette description s'appuie sur des concepts de la mécanique du solide, de la physiologie et anatomie du système musculosquelettique. Des exemples concrêts de développement d'implants sont aussi traités.

Engineering of musculoskeletal system and rehabilitation

BIO-687

This course presents today research questions and methods associated to the musculoskeletal system, its pathologies, and treatment.

Méthodes expérimentales en biomécanique

ME-380

Le but de ce cours est de permettre aux étudiants de se familiariser avec des techniques de base de mesures des propriétés mécaniques de différents tissus musculo squelettiques ou biomatériaux utilisés en ingénierie tissulaire.