Dominique Pioletti
EPFL STI IBI-STI LBO
MED 3 2626 (Bâtiment MED)
Station 9
1015 Lausanne
+41 21 693 83 41
+41 21 693 07 43
Office:
MED 3 2626
EPFL
>
STI
>
IBI-STI
>
LBO
Web site: Web site: https://lbo.epfl.ch/
EPFL STI IBI-GE
MED 3 2626 (Bâtiment MED)
Station 9
1015 Lausanne
+41 21 693 83 41
Office:
MED 3 2626
EPFL
>
STI
>
IBI-STI
>
IBI-STI-GE
Web site: Web site: https://bioengineering.epfl.ch/
+41 21 693 83 41
EPFL
>
STI
>
STI-SGM
>
SGM-ENS
EPFL STI IGM-GE
MED 3 2626 (Bâtiment MED)
Station 9
1015 Lausanne
+41 21 693 83 41
Office:
MED 3 2626
EPFL
>
STI
>
IGM
>
IGM-GE
EPFL STI DLL-STI
MED 3 1019 (Bâtiment MED)
Station 9
1015 Lausanne
+41 21 693 83 41
Office:
MED 3 1019
EPFL
>
STI
>
DLL-STI
>
DLL-STI-MATB
Fields of expertise
- Orthopedic Biomechanics
- Tissue Engineering
- Mechano-Biology
- Tissue Engineering
- Mechano-Biology
Mission
The Laboratory of Biomechanical Orthopedics (LBO) is dedicated to the advancement of techniques and technology for patient care in the musculo-skeletal system, through fundamental research, applied research, and teachingCurrent work
Through biomechanical considerations, Dominique PiolettiBiography
Dominique Pioletti received his Master in Physics from the Swiss Federal Institute of Technology Lausanne (EPFL) in 1992. He pursued his education in the same Institution and obtained his PhD in biomechanics in 1997. He developed original constitutive laws taking into account viscoelasticity in large deformations. Then he spent two years at UCSD as post-doc fellow acquiring know-how in cell and molecular biology. He was interested in particular to gene expression of bone cells in contact to orthopedic implant. In April 2006, Dominique Pioletti was appointed Assistant Professor tenure-track at the EPFL and is director of the Laboratory of Biomechanical Orthopedics. His research topics include biomechanics and tissue engineering of musculo-skeletal tissues; mechano-transduction in bone; development of orthopedic implant as drug delivery system. Since 2013, he has been promoted to the rank of Associate Professor.Publications
Infoscience publications
Journal paper and review
2024
Design of Customized Mouthguards with Superior Protection Using Digital-Based Technologies and Impact Tests
Sports Medicine-Open. 2024-05-31. DOI : 10.1186/s40798-024-00728-2.Glenohumeral joint force prediction with deep learning
Journal Of Biomechanics. 2024-01-15. DOI : 10.1016/j.jbiomech.2024.111952.Impact of Molecular Dynamics of Polyrotaxanes on Chondrocytes in Double-Network Supramolecular Hydrogels under Physiological Thermomechanical Stimulation
Biomacromolecules. 2024-01-02. DOI : 10.1021/acs.biomac.3c01132.2023
Unraveling cartilage degeneration through synergistic effects of hydrostatic pressure and biomimetic temperature increase
Iscience. 2023-12-03. DOI : 10.1016/j.isci.2023.108519.Enhancing Robustness of Adhesive Hydrogels through PEG-NHS Incorporation
Acs Applied Materials & Interfaces. 2023-10-23. DOI : 10.1021/acsami.3c13062.Wet adhesive hydrogels to correct malacic trachea (tracheomalacia) A proof of concept
Iscience. 2023-07-21. DOI : 10.1016/j.isci.2023.107168.A guide to preclinical evaluation of hydrogel-based devices for treatment of cartilage lesions
Acta Biomaterialia. 2023-02-16. DOI : 10.1016/j.actbio.2023.01.015.Mimicking Loading-Induced Cartilage Self-Heating in Vitro Promotes Matrix Formation in Chondrocyte-Laden Constructs with Different Mechanical Properties
Acs Biomaterials Science & Engineering. 2023-02-13. DOI : 10.1021/acsbiomaterials.2c00723.2022
NIR Light-Mediated Photocuring of Adhesive Hydrogels for Noninvasive Tissue Repair via Upconversion Optogenesis
Biomacromolecules. 2022-11-15. DOI : 10.1021/acs.biomac.2c00811.Age- and sex-specific normative values of bone mineral density in the adult glenoid
Journal Of Orthopaedic Research. 2022-06-01. DOI : 10.1002/jor.25379.Temperature evolution following joint loading promotes chondrogenesis by synergistic cues via calcium signaling
Elife. 2022-03-08. DOI : 10.7554/eLife.72068.2021
A Matlab toolbox for scaled-generic modeling of shoulder and elbow
Scientific Reports. 2021-10-21. DOI : 10.1038/s41598-021-99856-y.Silk granular hydrogels self-reinforced with regenerated silk fibroin fibers
Soft Matter. 2021-07-08. DOI : 10.1039/D1SM00585E.An Intrinsically-Adhesive Family of Injectable and Photo-Curable Hydrogels with Functional Physicochemical Performance for Regenerative Medicine
Macromolecular Rapid Communications. 2021-04-08. DOI : 10.1002/marc.202000660.An Off-the-Shelf Tissue Engineered Cartilage Composed of Optimally Sized Pellets of Cartilage Progenitor/Stem Cells
Acs Biomaterials Science & Engineering. 2021-03-08. DOI : 10.1021/acsbiomaterials.9b01863.Development of Standardized Fetal Progenitor Cell Therapy for Cartilage Regenerative Medicine: Industrial Transposition and Preliminary Safety in Xenogeneic Transplantation
Biomolecules. 2021-02-09. DOI : 10.3390/biom11020250.Pulsatile Flow-Induced Fatigue-Resistant Photopolymerizable Hydrogels for the Treatment of Intracranial Aneurysms
Frontiers in Bioengineering and Biotechnology. 2021-01-20. DOI : 10.3389/fbioe.2020.619858.Thoughts on cartilage tissue engineering: A 21st century perspective
Current Research in Translational Medicine. 2021-06-27. DOI : 10.1016/j.retram.2021.103299.Muscle co-contraction in an upper limb musculoskeletal model: EMG-assisted vs. standard load-sharing
Computer Methods in Biomechanics and Biomedical Engineering. 2021. DOI : 10.1080/10255842.2020.1814755.Feasibility of an alternative method to estimate glenohumeral joint center from videogrammetry measurements and CT/MRI of patients
Computer Methods In Biomechanics And Biomedical Engineering. 2021. DOI : 10.1080/10255842.2020.1808889.2020
Glenoid bone strain after anatomical total shoulder arthroplasty: In vitro measurements with micro-CT and digital volume correlation
Medical Engineering & Physics. 2020-09-23. DOI : 10.1016/j.medengphy.2020.09.009.Hybrid granular hydrogels: combining composites and microgels for extended ranges of material properties
Soft Matter. 2020-04-21. DOI : 10.1039/d0sm00213e.In vitro Implementation of Photopolymerizable Hydrogels as a Potential Treatment of Intracranial Aneurysms
Frontiers in Bioengineering and Biotechnology. 2020-04-03. DOI : 10.3389/fbioe.2020.00261.Light-Activated, Bioadhesive, Poly(2-hydroxyethyl methacrylate) Brush Coatings
Biomacromolecules. 2020-01-01. DOI : 10.1021/acs.biomac.9b01196.Efficient decellularization of equine tendon with preserved biomechanical properties and cytocompatibility for human tendon surgery indications
Artificial Organs. 2020. DOI : 10.1111/aor.13581.2019
Control of Dissipation Sources: A Central Aspect for Enhancing the Mechanical and Mechanobiological Performances of Hydrogels
ACS Applied Materials & Interfaces. 2019-10-30. DOI : 10.1021/acsami.9b15450.Knitted Silk-Collagen Scaffold Incorporated with Ligament Stem/Progenitor Cells Sheet for Anterior Cruciate Ligament Reconstruction and Osteoarthritis Prevention
ACS Biomaterials Science & Engineering. 2019-10-01. DOI : 10.1021/acsbiomaterials.9b01041.Patellar bone strain after total knee arthroplasty is correlated with bone mineral density and body mass index
Medical Engineering & Physics. 2019. DOI : 10.1016/j.medengphy.2019.03.017.2018
Composite Double-Network Hydrogels To Improve Adhesion on Biological Surfaces
ACS Applied Materials & Interfaces. 2018. DOI : 10.1021/acsami.8b10735.Tailoring swelling to control softening mechanisms during cyclic loading of PEG/cellulose hydrogel composites
Composites Science and Technology. 2018. DOI : 10.1016/j.compscitech.2018.08.043.Decellularised tissues obtained by a CO2-philic detergent and supercritical CO2
European Cells and Materials. 2018. DOI : 10.22203/eCM.v036a07.Non-setting, injectable biomaterials containing particulate hydroxyapatite can increase primary stability of bone screws in cancellous bone
Clinical Biomechanics. 2018. DOI : 10.1016/j.clinbiomech.2018.09.023.Cyclic loading of a cellulose/hydrogel composite increases its fracture strength
Extreme Mechanics Letters. 2018. DOI : 10.1016/j.eml.2018.09.002.Activation of AKT-mTOR Signaling Directs Tenogenesis of Mesenchymal Stem Cells
STEM CELLS. 2018. DOI : 10.1002/stem.2765.Effect of temporal onsets of mechanical loading on bone formation inside a tissue engineering scaffold combined with cell therapy
Bone Reports. 2018. DOI : 10.1016/j.bonr.2018.04.008.Depth-dependent mechanical properties of human articular cartilage obtained by indentation measurements
Journal of Materials Science: Materials in Medicine. 2018. DOI : 10.1007/s10856-018-6066-0.Fatigue as the missing link between bone fragility and fracture
Nature Biomedical Engineering. 2018. DOI : 10.1038/s41551-017-0183-9.Effect of a collar on subsidence and local micromotion of cementless femoral stems: in vitro comparative study based on micro-computerised tomography
International Orthopaedics. 2018. DOI : 10.1007/s00264-017-3524-0.2017
3D Printing of Polymers with Hierarchical Continuous Porosity
Advanced Materials Technologies. 2017. DOI : 10.1002/admt.201700145.A simulation framework for humeral head translations
Medical Engineering and Physics. 2017. DOI : 10.1016/j.medengphy.2017.08.013.Development of an effective cell seeding technique: simulation, implementation and analysis of contributing factors
Tissue Engineering C. 2017. DOI : 10.1089/ten.tec.2017.0108.Ectopic tissue engineered ligament with silk collagen scaffold for ACL regeneration: A preliminary study
Acta Biomaterialia. 2017. DOI : 10.1016/j.actbio.2017.02.027.Alignment of collagen fiber in knitted silk scaffold for functional massive rotator cuff repair
Acta Biomaterialia. 2017. DOI : 10.1016/j.actbio.2017.01.041.Micromotion-induced peri-prosthetic fluid flow around a cementless femoral stem
Computer Methods in Biomechanics and Biomedical Engineering. 2017. DOI : 10.1080/10255842.2017.1296954.Importance of trabecular anisotropy in finite element predictions of patellar strain after Total Knee Arthroplasty
Medical Engineering & Physics. 2017. DOI : 10.1016/j.medengphy.2016.10.003.Human bone progenitor cells for clinical application: what kind of immune reaction does fetal xenograft tissue trigger in immuno-competent rats?
Cell Transplantation. 2017. DOI : 10.3727/096368916X693789.Effects of glenoid inclination and acromion index on humeral head translation and glenoid articular cartilage strain
Journal of Shoulder and Elbow Surgery. 2017. DOI : 10.1016/j.jse.2016.05.031.In vitro and in vivo investigation of bisphosphonate-loaded hydroxyapatite particles for peri-implant bone augmentation
Journal of Tissue Engineering and Regenerative Medicine. 2017. DOI : 10.1002/term.2094.2016
Full-field measurement of micromotion around a cementless femoral stem using micro-CT imaging and radiopaque markers
Journal of Biomechanics. 2016. DOI : 10.1016/j.jbiomech.2016.10.029.Identification of elastic properties of human patellae using micro-finite element analysis
Journal of Biomechanics. 2016. DOI : 10.1016/j.jbiomech.2016.07.031.Experimental method to characterize the strain dependent permeability of tissue engineering scaffolds
Journal of Biomechanics. 2016. DOI : 10.1016/j.jbiomech.2016.09.021.Osteogenesis imperfecta: from diagnosis and multidisciplinary treatment to future perspectives
Swiss Medical Weekly. 2016. DOI : 10.4414/smw.2016.14322.Stability enhancement using hyaluronic acid gels for delivery of human fetal progenitor tenocytes
Cell Medicine. 2016. DOI : 10.3727/215517916X690486.A photopolymerized composite hydrogel and surgical implanting tool for a nucleus pulposus replacement
Biomaterials. 2016. DOI : 10.1016/j.biomaterials.2016.02.015.Anti-microbial dendrimers against multidrug-resistant P. aeruginosa enhance the angiogenic effect of biological burn-wound bandages
Scientific Reports. 2016. DOI : 10.1038/srep22020.A patient-specific model of total knee arthroplasty to estimate patellar strain: A case study
Clinical Biomechanics. 2016. DOI : 10.1016/j.clinbiomech.2015.11.008.Biodegradable HEMA-based hydrogels with enhanced mechanical properties
Journal of Biomedical Materials Research Part B. 2016. DOI : 10.1002/jbm.b.33469.2015
Miniature probe for the delivery and monitoring of a photopolymerizable material
Journal of Biomedical Optics. 2015. DOI : 10.1117/1.Jbo.20.12.127001.Effect of partial-thickness tear on loading capacities of the supraspinatus tendon: a finite element analysis
Computer Methods in Biomechanics and Biomedical Engineering. 2015. DOI : 10.1080/10255842.2015.1075012.Photo-polymerization, swelling and mechanical properties of cellulose fibre reinforced poly(ethylene glycol) hydrogels
Composites Science and Technology. 2015. DOI : 10.1016/j.compscitech.2015.10.002.Strategies for improving the repair of focal cartilage defects
Nanomedicine. 2015. DOI : 10.2217/nnm.15.119.Novel micropatterns mechanically control fibrotic reactions at the surface of silicone implants
Biomaterials. 2015. DOI : 10.1016/j.biomaterials.2015.03.027.Variability of the pullout strength of cancellous bone screws with cement augmentation
Clinical Biomechanics -Bristol-. 2015. DOI : 10.1016/j.clinbiomech.2015.03.003.Comparison of an EMG-based and a stress-based method to predict shoulder muscle forces
Computer Methods In Biomechanics And Biomedical Engineering. 2015. DOI : 10.1080/10255842.2014.899587.Time course of bone screw fixation following a local delivery of zoledronate in a rat femoral model – a micro-finite element analysis
Journal of the Mechanical Behavior of Biomedical Materials. 2015. DOI : 10.1016/j.jmbbm.2015.01.007.Impact of synovial fluid flow on temperature regulation in knee cartilage
Journal of Biomechanics. 2015. DOI : 10.1016/j.jbiomech.2014.11.008.Improving hydrogels’ toughness by increasing the dissipative properties of their network
Journal of the Mechanical Behavior of Biomedical Materials. 2015. DOI : 10.1016/j.jmbbm.2014.10.010.Mechanical evaluation of a tissue-engineered zone of calcification in a bone-hydrogel osteochondral construct
Computer Methods in Biomechanics and Biomedical Engineering. 2015. DOI : 10.1080/10255842.2013.794898.2014
Does locally delivered Zoledronate influence peri-implant bone formation? – Spatio-temporal monitoring of bone remodeling in vivo
Biomaterials. 2014. DOI : 10.1016/j.biomaterials.2014.09.005.Energy dissipation as a mechanobiological variable inducing chondrogenesis
Journal Of Tissue Engineering And Regenerative Medicine. 2014.Photopolymerizable hydrogels for implants: Monte-Carlo modeling and experimental in vitro validation
Journal of Biomedical Optics. 2014. DOI : 10.1117/1.Jbo.19.3.035004.The role of energy dissipation of polymeric scaffolds in the mechanobiological modulation of chondrogenic expression
Biomaterials. 2014. DOI : 10.1016/j.biomaterials.2013.11.048.Intrinsic viscoelasticity increases temperature in knee cartilage under physiological loading
Journal of the Mechanical Behavior of Biomedical Materials. 2014. DOI : 10.1016/j.jmbbm.2013.10.025.Controlled release from a mechanically-stimulated thermosensitive self-heating composite hydrogel
Biomaterials. 2014. DOI : 10.1016/j.biomaterials.2013.09.065.Translation of biomechanical concepts in bone tissue engineering: from animal study to revision knee arthroplasty
Computer Methods in Biomechanics and Biomedical Engineering. 2014. DOI : 10.1080/10255842.2012.719607.2013
Activities of daily living with reverse prostheses: importance of scapular compensation for functional mobility of the shoulder
Journal Of Shoulder And Elbow Surgery. 2013. DOI : 10.1016/j.jse.2012.09.014.Cartilage self-heating contributes to chondrogenic expression
European Cells and Materials. 2013. DOI : 10.22203/eCM.v026a12.Capillary-valve-based platform towards cell-on-chip mechanotransduction assays
Sensors and Actuators B. 2013. DOI : 10.1016/j.snb.2013.07.050.A flow sensing model for mesenchymal stromal cells using morphogen dynamics
Biophysical Journal. 2013. DOI : 10.1016/j.bpj.2013.04.014.Importance of the subscapularis muscle after total shoulder arthroplasty
Clinical Biomechanics. 2013. DOI : 10.1016/j.clinbiomech.2012.11.010.Response to Letter to the Editor: Comment on "injectable calcium phosphate cement for augmentation around cancellous bone screws. In vivo biomechanical studies"
Journal Of Biomechanics. 2013. DOI : 10.1016/j.jbiomech.2012.09.024.Integration of mechanotransduction concepts in bone tissue engineering
Computer Methods in Biomechanics and Biomedical Engineering. 2013. DOI : 10.1080/10255842.2013.780602.Effect of a pathological scapular tilt after total shoulder arthroplasty
Computer Methods in Biomechanics and Biomedical Engineering. 2013. DOI : 10.1080/10255842.2012.656612.2012
Synthesis and photopolymerization of Tween 20 Methacrylate/N-vinyl-2-Pyrrolidone blend
Materials Science and Engineering C. 2012. DOI : 10.1016/j.msec.2012.06.009.Damping properties of the nucleus pulposus
Clinical Biomechanics -Bristol-. 2012. DOI : 10.1016/j.clinbiomech.2012.06.005.Epiphyseal chondro-progenitors provide a stable cell source for cartilage cell therapy
Cell Medicine. 2012. DOI : 10.3727/215517912X639324.Injectable calcium phosphate cement for augmentation around cancellous bone screws. In vivo biomechanical studies
Journal of Biomechanics. 2012. DOI : 10.1016/j.jbiomech.2012.02.004.Simultaneous and multisite measure of micromotion, subsidence and gap to evaluate femoral stem stability
Journal of Biomechanics. 2012. DOI : 10.1016/j.jbiomech.2012.01.040.Importance of polyethylene thickness in total shoulder arthroplasty: A finite element analysis
Clinical Biomechanics. 2012. DOI : 10.1016/j.clinbiomech.2011.12.003.2011
In vivo loading increases mechanical properties of scaffold by affecting bone formation and bone resorption rates
Bone. 2011. DOI : 10.1016/j.bone.2011.09.040.Nanofibrillated cellulose composite hydrogel for the replacement of the nucleus pulposus
Acta biomaterialia. 2011. DOI : 10.1016/j.actbio.2011.05.029.In vivo assessment of local effects after application of bone screws delivering bisphosphonates into a compromised cancellous bone site
Clinical Biomechanics -Bristol-. 2011. DOI : 10.1016/j.clinbiomech.2011.06.004.Prediction of spatio-temporal bone formation in scaffold by diffusion equation
Biomaterials. 2011. DOI : 10.1016/j.biomaterials.2011.05.085.Biomechanics and tissue engineering
Osteoporosis International. 2011. DOI : 10.1007/s00198-011-1616-z.Biologicals and fetal cell therapy for wound healing and scar management
ISRN Dermatology. 2011. DOI : 10.5402/2011/549870.Bone regeneration and stem cells
Journal of Cellular and Molecular Medicine. 2011. DOI : 10.1111/j.1582-4934.2010.01224.x.Human fetal bone cells in delivery systems for bone engineering
Journal of Tissue Engineering and Regenerative Medicine. 2011. DOI : 10.1002/term.381.Regulation of proliferation and differentiation of human fetal bone cells
European Cells and Materials. 2011. DOI : 10.22203/eCM.v021a04.Surgical preparation of bone-scaffold interface is critical for bone regeneration inside tissue engineering scaffold
Journal of Orthopaedic Research. 2011. DOI : 10.1002/jor.21290.A new technique to measure micromotion distribution around a cementless femoral stem
Journal of Biomechanics. 2011. DOI : 10.1016/j.jbiomech.2010.09.023.Combined effects of zoledronate and mechanical stimulation on bone adaptation in an axially loaded mouse tibia
Clinical Biomechanics. 2011. DOI : 10.1016/j.clinbiomech.2010.08.014.2010
Calcium phosphate augmentation of cancellous bone screws in impaired lapine bone (vol 40, pg S23, 2009)
Injury-International Journal Of The Care Of The Injured. 2010. DOI : 10.1016/j.injury.2009.09.026.The skeletal key
Public Service Review: Science and Technology. 2010.From bench to bedside
EPC Drug Discovery, Delivery & Therapeutics. 2010.Curing Kinetics and Mechanical Properties of a Composite Hydrogel for the Replacement of the Nucleus Pulposus
Composites Science and Technology. 2010. DOI : 10.1016/j.compscitech.2010.07.018.Biomechanical consequences of humeral component malpositioning after anatomical total shoulder arthroplasty
Journal of Shoulder and Elbow Surgery. 2010. DOI : 10.1016/j.jse.2010.06.006.Calcium phosphate cement augmentation of cancellous bone screws can compensate for the absence of cortical fixation
Journal of Biomechanics. 2010. DOI : 10.1016/j.jbiomech.2010.07.025.A musculoskeletal shoulder model based on pseudo-inverse and null-space optimization
Medical Engineering and Physics. 2010. DOI : 10.1016/j.medengphy.2010.07.006.Tightening force and torque of nonlocking screws in a reverse shoulder prosthesis
Clinical Biomechanics -Bristol-. 2010. DOI : 10.1016/j.clinbiomech.2010.03.011.Augmentation of bone defect healing using a new biocomposite scaffold: an in vivo study in sheep
Acta Biomaterialia. 2010. DOI : 10.1016/j.actbio.2010.03.028.Plasticity of fetal cartilaginous cells
Cell Transplantation. 2010. DOI : 10.3727/096368910X506854.In vivo cyclic loading as a potent stimulatory signal for bone formation inside tissue engineering scaffolds
European Cells and Materials. 2010. DOI : 10.22203/ecm.v019a05.Biomechanics in bone tissue engineering
Computer Methods In Biomechanics And Biomedical Engineering. 2010. DOI : 10.1080/10255841003630660.Mechanical interaction between cells and fluid for bone tissue engineering scaffold: modulation of the interfacial shear stress
Journal of Biomechanicsanics. 2010. DOI : 10.1016/j.jbiomech.2009.11.004.2009
3D strain map of axially loaded mouse tibia: a numerical analysis validated by experimental measurements
Computer Methods In Biomechanics And Biomedical Engineering. 2009. DOI : 10.1080/10255840802178053.Comparison of polyethylene wear in anatomical and reversed shoulder prostheses
Journal of Bone and Joint Surgery [Br]. 2009. DOI : 10.1302/0301-620X.91B7.21999.Prediction of bone density around orthopedic implants delivering bisphosphonate
Journal of Biomechanicsanics. 2009. DOI : 10.1016/j.jbiomech.2009.03.024.Whole-cell bioprocessing of human fetal cells for tissue engineering of skin
Skin Pharmacol Physio. 2009. DOI : 10.1159/000178865.Isolation and in vitro chondrogenic potential of human fetal spine cells
Journal of Cellular and Molecular Medicine. 2009. DOI : 10.1111/j.1582-4934.2008.00630.x.Total shoulder arthroplasty: Downward inclination of the glenoid component to balance supraspinatus deficiency
Journal of Shoulder and Elbow Surgery. 2009. DOI : 10.1016/j.jse.2008.11.008.Targeted mechanical properties for optimal fluid motion inside artificial bone substitutes
Journal of Orthopedic Research. 2009. DOI : 10.1002/jor.20836.Biomechanical evaluation of porous biodegradable scaffolds for revision knee arthroplasty
Computer Methods in Biomechanics and Biomedical Engineering. 2009. DOI : 10.1080/10255840802603589.Chronic wound healing by fetal cell therapy may be explained by differential gene profiling observed in fetal versus old skin cells
Exp Gerontology. 2009. DOI : 10.1016/j.exger.2008.11.004.In vitro characterization of immune-related properties of human fetal bone cells for potential tissue engineering applications
Tissue Engineering. 2009. DOI : 10.1089/ten.tea.2008.0222.Osteoclastogenesis can be mechanically-induced in the peri-implant bone
Biomedical Engineering and Research. 2009. DOI : 10.1016/j.irbm.2008.10.003.3D strain map of axially loaded mouse tibia: a numerical analysis validated by experimental measurements
Comput Methods Biomech Biomed Engin. 2009. DOI : 10.1080/10255840903094035.2008
Implants delivering bisphosphonate locally increase periprosthetic bone density in an osteoporotic sheep model. A pilot study
European Cells and Materials. 2008. DOI : 10.22203/ecm.v016a02.Human muscular fetal cells: a potential cell source for muscular therapies
Pediatr Surg Int. 2008. DOI : 10.1007/s00383-007-2040-5.Human fetal bone cells associated with ceramic reinforced PLA scaffolds for tissue engineering
Bone. 2008. DOI : 10.1016/j.bone.2007.10.018.Wound healing gene-family expression differences between fetal and foreskin cells used for bioengineered skin substitutes
Artificial Organs. 2008. DOI : 10.1111/j.1525-1594.2008.00578.x.Microstimulations at the bone implant interface upregulate osteoclast activation pathway
Bone. 2008. DOI : 10.1016/j.bone.2007.09.055.Orthopedic implant used as drug delivery system: clinical situation and state of the research
Current Drug Delivery. 2008.2007
Repair of critical size defects in the rat cranium using ceramic-reinforced PLA scaffolds obtained by supercritical gas foaming
Journal of Biomedical Materials Research Part A. 2007. DOI : 10.1002/jbm.a.31208.Consistency of fetal cell banks for research and clinical use
Cell Transplantation. 2007. DOI : 10.3727/000000007783465127.Biomechanical evaluation of intra-articular and extra-articular procedures in anterior cruciate ligament reconstruction: A finite element analysis
Clinical Biomechanics. 2007. DOI : 10.1016/j.clinbiomech.2006.10.006.Polylactic acid-phosphate glass composite foams as scaffolds for tissue engineering
J Biomed Mater Res B. 2007. DOI : 10.1002/jbmb.2006
Polylactic Acid–Phosphate Glass Composite Foams as Scaffolds for Bone Tissue Engineering
Journal of Biomedical Materials Research Part B. 2006. DOI : 10.1002/jbm.b.30600.Architecture and properties of anisotropic polymer composite scaffolds for bone tissue engineering
Biomaterials. 2006. DOI : 10.1016/j.biomaterials.2005.07.015.Bone tissue engineering using fetal cell therapy
Swiss Medical Weekly. 2006. DOI : 10.4414/smw.2006.11411.Total joint replacement and aseptic loosening
Helix Review Series Rheumatology. 2006.Local delivery of bisphosphonate from coated orthopedic implants increases implants mechanical stability in osteoporotic rats
Journal of Biomedical Materials Research Part A. 2006. DOI : 10.1002/jbm.a.30456.2005
The effect of bisphosphonates and titanium particles on osteoblasts: an in vitro study
Journal of Bone and Joint Surgery. 2005. DOI : 10.1302/0301-620X.87B8.15446.Calcium phosphate drug delivery system: influence of local zoledronate release on bone implant osteointegration
Bone. 2005. DOI : 10.1016/j.bone.2004.10.004.Biocompatibility of bioresorbable poly(L-lactic acid) composite scaffolds obtained by supercritical gas foaming with human fetal bone cells
Tissue Engineering. 2005. DOI : 10.1089/ten.2005.11.1640.How plate positioning impacts the biomechanics of the open wedge tibial osteotomy; a finite element analysis
Comput Methods Biomech Biomed Engin. 2005. DOI : 10.1080/10255840500322433.Bioresorbable composites prepared by supercritical fluid foaming
Journal of Biomedical Materials Research Part A. 2005. DOI : 10.1002/jbm.a.30385.2004
Can the increase of bone mineral density following bisphosphonates treatments be explained by biomechanical considerations?
Clinical Biomechanics. 2004. DOI : 10.1016/j.clinbiomech.2003.10.002.The influence of wear particles in the expression of osteoclastogenesis factors by osteoblasts
Biomaterials. 2004. DOI : 10.1016/j.biomaterials.2004.01.053.Peri-implant bone remodeling after total hip replacement combined with systemic alendronate treatment: a finite element analysis
Comput Methods Biomech Biomed Engin. 2004. DOI : 10.1080/1025584042000205327.Fetal bone cells for tissue engineering
Bone. 2004. DOI : 10.1016/j.bone.2004.07.001.2003
Effect of micromechanical stimulations on osteoblasts: development of a device simulating the mechanical situation at the bone-implant interface
Journal of Biomechanics. 2003. DOI : 10.1016/S0021-9290(02)00301-9.Biphasic constitutive laws for biological interface evolution
Biomech Model Mechanobiol. 2003. DOI : 10.1007/s10237-002-0024-x.2002
Gene expression analysis of osteoblastic cells contacted by orthopedic implant particles
J Biomed Mater Res. 2002. DOI : 10.1002/jbm.10218.Effect of different Ti-6Al-4V surface treatments on osteoblasts behaviour
Biomaterials. 2002. DOI : 10.1016/S0142-9612(01)00266-6.Large-scale gene expression analysis of osteoblasts cultured on three different Ti-6Al-4V surface treatments
Biomaterials. 2002. DOI : 10.1016/S0142-9612(02)00161-8.2001
Orthopedic implant used as a drug delivery system: a numerical study
Computer Methods in Biomechanics and Biomedical Engineering. 2001. DOI : 10.1080/10255840108908023.2000
Combined effect of titanium particles and TNF-alpha on the production of IL-6 by osteoblast-like cells
Journal of Biomedical Materials Research. 2000. DOI : 10.1002/1097-4636(200011)52:2<382::AID-JBM19>3.0.CO;2-V.The effects of calcium phosphate cement particles on osteoblast functions
Biomaterials. 2000. DOI : 10.1016/S0142-9612(99)00250-1.On the independence of time and strain effects in the stress relaxation of ligaments and tendons
Journal of Biomechanics. 2000. DOI : 10.1016/S0021-9290(00)00128-7.Non-linear viscoelastic laws for soft biological tissues
European Journal of Mechanics a-Solids. 2000. DOI : 10.1016/S0997-7538(00)00202-3.Titanium particles inhibit osteoblast adhesion to fibronectin-coated substrates
J Orthopaed Res. 2000. DOI : 10.1002/jor.1100180207.1999
The cytotoxic effect of titanium particles phagocytosed by osteoblasts
J Biomed Mater Res. 1999. DOI : 10.1002/(SICI)1097-4636(19990905)46:3<399::AID-JBM13>3.0.CO;2-B.Strain rate effect on the mechanical behavior of the anterior cruciate ligament-bone complex
Medical Engineering & Physics. 1999. DOI : 10.1016/S1350-4533(99)00028-4.1998
Intrinsic coordinate system for the tibial plateau
Knee. 1998. DOI : 10.1016/S0968-0160(97)10008-4.Viscoelastic constitutive law in large deformations: application to human knee ligaments and tendons
Journal of Biomechanics. 1998. DOI : 10.1016/S0021-9290(98)00077-3.1997
Tibial component positioning in total knee arthroplasty: bone coverage and extensor apparatus alignment
knee surgery sports traumatology arthroscopy. 1997. DOI : 10.1007/s001670050059.Displacements of the tibial tuberosity - Effects of the surgical parameters
Clinical Orthopaedics and Related Research. 1997.1995
Experimental and mathematical methods for representing relative surface elongation of the ACL
Journal of Biomechanics. 1995. DOI : 10.1016/0021-9290(94)00160-6.1994
Cinématique et élongation contiue du ligament croisé antérieur [Kinematics and continuous elongation of the anterior cruciate ligament]
Revue médicale de la Suisse romande. 1994.Teaching & PhD
Teaching
Mechanical Engineering
PhD Students
Bouchez Mi-Lane Elodie, Eghbalishamsabadi Pezhman, Mohammadi Ramin, Nottegar Alexander Arthur, Raja Sruthi, Reitzel Antoine, Turgut Deniz Cemre, Varanges Vincent Marc,Past EPFL PhD Students
Abdel Sayed Philippe , Antons Jens , Blecha Luc , Boulanaache Yasmine , Darwiche Salim Elias , Engelhardt Christoph Anselm , Gortchacow Miguel , Guo Yanheng , Hausherr Tanja Cloé , Hollenstein Jérôme , Karami Peyman , Kettenberger Ulrike , Latypova Adeliya , Malfroy Camine Valérie Hélène Emilie , Marascio Matteo Gregorio Modesto , Montjovent Marc-Olivier , Nasrollahzadeh Mamaghani Naser , Nassajian Moghadam Mohamadreza , Poupart Oriane , Quintin Aurélie , Roshan Ghias Alireza , Sarshari Ehsan , Schmocker Andreas , Stadelmann Vincent , Stampoultzis Theofanis , Uslu Ece , Vogel Arne Christian , Wyss Céline Samira ,Courses
Engineering of musculoskeletal system and rehabilitation
This course presents today research questions and methods associated to the musculoskeletal system, its pathologies, and treatment.
Experimental methods in biomechanics
The aim of this course is to allow the students to become familiar with the basic techniques to measure the mechanical properties of different musculoskeletal tissues or biomaterials used in tissue engineering.
Biomechanics of the musculoskeletal system
The basis for a mechanical description of the musculoskeletal system are presented. This description is based on the concepts of solid mechanics, physiology and anatomy of the musculoskeletal system. Concrete examples of the development of implants are also covered.