Sylvie Roke
Nationality: Dutch
EPFL STI IBI-STI LBP
BM 4112 (Bâtiment BM)
Station 17
1015 Lausanne
+41 21 693 11 91
+41 21 693 10 42
Office:
BM 4112
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Website: https://gr-ost.epfl.ch/
Expertise
Aqueous interfaces and systems
Nonlinear optics
Ultrafast spectroscopy
Light scattering
Nonlinear and multiphoton imaging
Soft matter and membrane systems
Mission
Our strategy is to develop novel optical technology, geared to obtaining molecular level details of nanoscale and microscopic systems in aqueous environments as well as other complex 3D environments such as pores. We have focused on ultrafast nonlinear optical methods as they are non-invasive and label-free and inherently interface specific or sensitive to polar structures. We apply these tools to fundamental questions that have important implications for biology, chemistry or technology.
Topics of interest:
• Water, aqueous solutions
• Aqueous interfaces and nanoscopic systems
• Nonlinear optics, ultrafast spectroscopy, light scattering
• Multiphoton imaging
• Soft systems: Interfaces, membranes, electric double layers
• Structure and dynamics in living systems
• Neuroimaging and neurological activity
2011 – present: Julia Jacobi Chair in photomedicine, école Polytechnique Fédérale Lausanne (EPFL), CH.
2005 – 2012: Max Planck Research Group Leader (W2 /C3) of a centrally announced open theme independent research group. Host: The Max-Planck Institute for Metals Research, Stuttgart, DE.
2005 – 2005: Alexander von Humboldt Fellow, dept. of Applied Physical Chemistry, Heidelberg University, DE.
2004 – 2005: Postdoctoral Fellow, FOM-Institute for Plasma Physics, NL.
Awards and Distinctions
2021 - Elected Fellow of Optica (formerly Optical Society of America)
2020 - Winner of an ERC Synergy Grant
2020 - Elected Fellow of the American Physical Society
2020 - ERC Proof of Concept Grant
2019 - Featured for OSA living stories2014 - Winner of an ERC Consolidator Grant.
2013 - Cover and Featured Professional in the 2013-2014 SPIE Monthly Planner.
2011 - Julia Jacobi Chair in photomedicine.
2010 - Fellow of the Young Academy of the Berlin-Brandenburg Academy of Sciences and Humanities (BBAW) and the German Academy of Natural Scientists, Leopoldina.
2010 - Young member Werner von Siemens Ring (DE).
2010 - Selection for the Excellence Network of the Robert-Bosch Foundation (DE).
2009 - Winner of an ERC Startup Grant.
2008 - Hertha-Sponer-Preis awarded by the German Physical Society (DPG)
2007 - Young Researcher prize, ESF conference on Bio-interfaces, Saint Feliu, ES.
2006 - Minerva Prize awarded biyearly by the Dutch Foundation for Fundamental Research on Matter (FOM).
2006 - Featured Professional in «Brilliant Minds» for Germany's international broadcaster Deutsche Welle's Tomorrow Today (broadcast on television worldwide 06/2006).
2005 - Recipient of a Max Planck Research Group Leader position.
2005 - Recipient of an Alexander von Humboldt Fellowship.
2005 - Prize winner in a Dutch science writing contest of the Dutch Physical Society.
2004 - Ph. D. degree with highest honors, awarded to <5% of all candidates.
2003 - L. J. Oosterhoff prize, awarded by the University of Leiden.
2002 - Young Researcher prize of the «Holland Research School for Molecular Chemistry».
2001 - Young Researcher prize at the Gordon Research Conference on Surface Dynamics, New Hampshire, USA.
2000 - Cum Laude, M. Sc. in chemistry with highest honors, <10% of all candidates.
2000 - Cum Laude, M. Sc. in physics with highest honors, <10% of all candidates.
Education
PhD
| Natural Sciences2000 – 2004 Leiden University
M.Sc.
| Physics1997 – 2000 Utrecht University
M. Sc.
| Chemistry1995 – 2000 Utrecht University
Awards
Holland Research School for Molecular Chemistry Young Researcher prize
2002
L. J. Oosterhoff prize
2003
Alexander von Humboldt Fellowship
2005
Minerva Prize (Dutch Foundation for Fundamental Research on Matter
2006
Hertha-Sponer-Preis
DPG
2008
ERC Starting Grant
European Research Council
2009
Fellow of Leopoldina and BBAW
2010
ERC Consolidator Grant (2013). Julia Jacobi Chair in photomedicine@EPFL
European Research Council
2011
Holland Research School for Molecular Chemistry Young Researcher prize
2002
L. J. Oosterhoff prize
2003
Alexander von Humboldt Fellowship
2005
Minerva Prize (Dutch Foundation for Fundamental Research on Matter
2006
Hertha-Sponer-Preis
DPG
2008
ERC Starting Grant
European Research Council
2009
Fellow of Leopoldina and BBAW
2010
ERC Consolidator Grant (2013). Julia Jacobi Chair in photomedicine@EPFL
European Research Council
2011
Fellowship to the American Physical Society
American Physical Society
2020
Publications
Research
Research Highlights
Topics of interest:
• Water, aqueous solutions
• Aqueous interfaces and nanoscopic systems
• Nonlinear optics, ultrafast spectroscopy, light scattering
• Multiphoton imaging
• Soft systems: Interfaces, membranes, electric double layers
• Structure and dynamics in living systems
• Neuroimaging and neurological activity
10 Research Highlights (anti-chronological)
• Surface electrostatic potentials and reaction constants can be optically imaged in real time and display heterogeneities of respectively a factor of 3 x the average and 8 orders of magnitude on a glass micro-capillary surface immersed in water.
• Electrolytes induce changes in the hydrogen bond network of water that range over ~77 hydration shells and are subject to quantum effects. These changes lead to energy changes on the order of kT per ion, which lead to surface tension anomalies, better known as the controversial Jones-Ray effect (discovered in the 1930's).
• Discovery that (~50-150 nm) liposomes exhibit trans-membrane asymmetry in their hydration shells rather than the lipid composition. Specific interactions may induce membrane asymmetry.
• Development of a nanodroplet platform to study the molecular structure of lipid droplets and biological monolayer phenomena in solution.
• Discovery that various molecular properties of nanoscale / submicron droplets of oil and water behave differently than extended planar interfaces composed of the same chemicals; reasons can be found in the difference in hydrogen bond network configurations and a different balance of electrostatic interactions.
• Development of wide field medium repetition rate second harmonic and multiphoton imaging instruments with ~5000 x better efficiency than scanning confocal microscopy.
• Angle resolved second harmonic scattering can be used to measure unique surface potential values on particles in solution.
• Development of second harmonic scattering instrumentation with an improved efficiency of ~1000.
• Invention of vibrational sum frequency scattering, and subsequent development into a reliable interfacial molecular probe of buried interfaces of nano- and microscale materials.
• Development of nonlinear optical theories to understand nonlinear light scattering.
Teaching & PhD
PhD Students
Lena Dalifoski, Chaudhary Eksha Rani, Nelson Alonso Correa Rojas, Zhi Li, Iwona Swiderska, Kshitij Vivek Goyal, Viktor Vorobev, Angela Natalie Moskal
Past EPFL PhD Students
Hilton Barbosa De Aguiar, Rüdiger Scheu, Yixing Chen, Cornelis Lütgebaucks, Nikolay Smolentsev, Marie Eve Pascale Didier, Evangelia Zdrali, Orly Bagunu Tarun, Jan Dedic, Igor Nahálka, Nathan Dupertuis, Maksim Eremchev, Pierre-Marc Jean Marie Dansette, Sergey Kulik, Marie Bischoff, David Roesel, Tereza Schönfeldová, Seonwoo Lee, Bingxin Chu, Li Zhang, Mischa Flór
Past EPFL PhD Students as codirector
Courses
Nonlinear Spectroscopy
PHYS-613
To provide an introduction into the field of nonlinear spectroscopy, and focus in particular on linear and nonlinear light scattering